hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00001
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SMAD1 | Mothers against decapentaplegic homolog 1 (MAD homolog 1) (Mothers against DPP homolog 1) (JV4-1) (Mad-related protein 1) (SMAD family member 1) (SMAD 1) (Smad1) (hSMAD1) (Transforming growth factor-beta-signaling protein 1) (BSP-1) | UniProt NCBI |
| EHD1 | EH domain-containing protein 1 (PAST homolog 1) (hPAST1) (Testilin) | UniProt NCBI |
| TBCB | Tubulin-folding cofactor B (Cytoskeleton-associated protein 1) (Cytoskeleton-associated protein CKAPI) (Tubulin-specific chaperone B) | UniProt NCBI |
| ANXA6 | Annexin A6 (67 kDa calelectrin) (Annexin VI) (Annexin-6) (Calphobindin-II) (CPB-II) (Chromobindin-20) (Lipocortin VI) (Protein III) (p68) (p70) | UniProt NCBI |
| PAFAH1B2 | Platelet-activating factor acetylhydrolase IB subunit beta (EC 3.1.1.47) (PAF acetylhydrolase 30 kDa subunit) (PAF-AH 30 kDa subunit) (PAF-AH subunit beta) (PAFAH subunit beta) | UniProt NCBI |
| PAFAH1B3 | Platelet-activating factor acetylhydrolase IB subunit gamma (EC 3.1.1.47) (PAF acetylhydrolase 29 kDa subunit) (PAF-AH 29 kDa subunit) (PAF-AH subunit gamma) (PAFAH subunit gamma) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00565 | 0.00349258474935 | 0.333333333333 | PAFAH1B2 PAFAH1B3 | Ether lipid metabolism |
| GO:0047179 | 0.00676235117068 | 0.333333333333 | PAFAH1B2 PAFAH1B3 | platelet-activating factor acetyltransferase activity |
| REAC:R-HSA-6811436 | 0.0269276420577 | 0.333333333333 | PAFAH1B2 PAFAH1B3 | COPI-independent Golgi-to-ER retrograde traffic |
| MIRNA:hsa-miR-6824-3p | 0.0442415992422 | 0.333333333333 | ANXA6 PAFAH1B2 | hsa-miR-6824-3p |
| MIRNA:hsa-miR-6764-3p | 0.0461159505368 | 0.333333333333 | ANXA6 PAFAH1B2 | hsa-miR-6764-3p |
| CORUM:2642 | 0.0499726005494 | 0.166666666667 | SMAD1 | SMAD1-P300 complex |
| CORUM:2958 | 0.0499726005494 | 0.166666666667 | SMAD1 | SMAD1-CBP complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PAFAH1B2 | PAFAH1B3 | 0.985 | 0.899 | hein_WMM bioplex (PAFAH1B3) bioplex_WMM hein (PAFAH1B2) boldt_WMM |
| TBCB | PAFAH1B2 | 0.08 | 0.35 | bioplex_WMM gupta_WMM fraction treiber_WMM |
| ANXA6 | TBCB | 0.059 | 0.33 | bioplex_WMM youn_WMM gupta_WMM fraction |
| SMAD1 | TBCB | 0.05 | 0.298 | fraction |
| TBCB | PAFAH1B3 | 0.048 | 0.294 | bioplex_WMM gupta_WMM fraction treiber_WMM |
| EHD1 | PAFAH1B3 | 0.043 | 0.269 | bioplex_WMM fraction |
| EHD1 | PAFAH1B2 | 0.009 | 0.107 | bioplex_WMM fraction |
| ANXA6 | PAFAH1B2 | 0.007 | 0.011 | bioplex_WMM gupta_WMM WMM_only |
| ANXA6 | EHD1 | 0.007 | 0.0 | bioplex_WMM WMM_only treiber_WMM |
| ANXA6 | PAFAH1B3 | 0.007 | 0.005 | bioplex (PAFAH1B3) bioplex_WMM gupta_WMM |
| TBCB | EHD1 | 0.0 | 0.011 | bioplex_WMM fraction |
Images
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Complex HuMAP2_00001 has an average edge precision of 0.234 which is ranked 5629 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SMAD1 | HuMAP2_00001 HuMAP2_01252 HuMAP2_02037 HuMAP2_02752 HuMAP2_02905 HuMAP2_04429 |
| EHD1 | HuMAP2_00001 HuMAP2_02020 |
| TBCB | HuMAP2_00001 HuMAP2_02037 HuMAP2_02905 |
| ANXA6 | HuMAP2_00001 HuMAP2_02037 HuMAP2_02905 |
| PAFAH1B2 | HuMAP2_00001 HuMAP2_02037 HuMAP2_04820 |
| PAFAH1B3 | HuMAP2_00001 HuMAP2_02037 HuMAP2_04820 |