hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_00018
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ARSA | Arylsulfatase A (ASA) (EC 3.1.6.8) (Cerebroside-sulfatase) [Cleaved into: Arylsulfatase A component B; Arylsulfatase A component C] | UniProt NCBI |
| GALNS | N-acetylgalactosamine-6-sulfatase (EC 3.1.6.4) (Chondroitinsulfatase) (Chondroitinase) (Galactose-6-sulfate sulfatase) (GalN6S) (N-acetylgalactosamine-6-sulfate sulfatase) (GalNAc6S sulfatase) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04142 | 0.00100713074717 | 1.0 | ARSA GALNS | Lysosome |
| GO:0004065 | 0.0247952876258 | 1.0 | ARSA GALNS | arylsulfatase activity |
| REAC:R-HSA-2206290 | 0.0249595281251 | 0.5 | GALNS | MPS IV - Morquio syndrome A |
| KEGG:00531 | 0.0369186440558 | 0.5 | GALNS | Glycosaminoglycan degradation |
| GO:0008484 | 0.0410249304355 | 1.0 | ARSA GALNS | sulfuric ester hydrolase activity |
| HP:0005609 | 0.0497341708567 | 0.5 | ARSA | Gallbladder dysfunction |
| HP:0012070 | 0.0497341708567 | 0.5 | GALNS | Chondroitin sulfate excretion in urine |
| HP:0030865 | 0.0497341708567 | 0.5 | GALNS | Large elbow |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ARSA | GALNS | 0.918 | 0.841 | bioplex (ARSA) bioplex_WMM |
Images
Click to enlarge
Complex HuMAP2_00018 has an average edge precision of 0.841 which is ranked 809 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ARSA | HuMAP2_00018 HuMAP2_02252 HuMAP2_03210 HuMAP2_07005 |
| GALNS | HuMAP2_00018 HuMAP2_03210 HuMAP2_07005 |