hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00029
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| GNAS | Neuroendocrine secretory protein 55 (NESP55) [Cleaved into: LHAL tetrapeptide; GPIPIRRH peptide] | UniProt NCBI |
| OCIAD1 | OCIA domain-containing protein 1 (Ovarian cancer immunoreactive antigen domain containing 1) (Ovarian carcinoma immunoreactive antigen) | UniProt NCBI |
| MAGED2 | Melanoma-associated antigen D2 (11B6) (Breast cancer-associated gene 1 protein) (BCG-1) (Hepatocellular carcinoma-associated protein JCL-1) (MAGE-D2 antigen) | UniProt NCBI |
| GNAL | Guanine nucleotide-binding protein G(olf) subunit alpha (Adenylate cyclase-stimulating G alpha protein, olfactory type) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0012049 | 0.00102214412276 | 0.5 | GNAS GNAL | Laryngeal dystonia |
| WP:WP35 | 0.00623747495525 | 0.5 | GNAS GNAL | G Protein Signaling Pathways |
| WP:WP4540 | 0.00623747495525 | 0.5 | GNAS GNAL | Pathways Regulating Hippo Signaling |
| KEGG:05146 | 0.00710001811334 | 0.5 | GNAS GNAL | Amoebiasis |
| KEGG:05142 | 0.00761107721317 | 0.5 | GNAS GNAL | Chagas disease (American trypanosomiasis) |
| KEGG:04728 | 0.014392043024 | 0.5 | GNAS GNAL | Dopaminergic synapse |
| KEGG:04020 | 0.0248155779574 | 0.5 | GNAS GNAL | Calcium signaling pathway |
| CORUM:7097 | 0.0499140284799 | 0.25 | GNAS | GNAS-L-GNB1-GNG1 complex |
| CORUM:7143 | 0.0499140284799 | 0.25 | GNAS | GNAS-L-GNB2-GNG1 complex |
| CORUM:7144 | 0.0499140284799 | 0.25 | GNAS | GNAS-L-GNB3-GNG1 complex |
| CORUM:7145 | 0.0499140284799 | 0.25 | GNAS | GNAS-L-GNB4-GNG1 complex |
| CORUM:7146 | 0.0499140284799 | 0.25 | GNAS | GNAS-L-GNB1-GNG1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| GNAS | GNAL | 1.0 | 0.949 | bioplex (GNAS) bioplex_WMM gupta_WMM boldt_WMM |
| GNAS | MAGED2 | 0.993 | 0.918 | bioplex (GNAS,MAGED2) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| GNAS | OCIAD1 | 0.602 | 0.67 | bioplex (GNAS) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| MAGED2 | GNAL | 0.03 | 0.233 | bioplex (MAGED2) bioplex_WMM gupta_WMM boldt_WMM |
| GNAL | OCIAD1 | 0.007 | 0.008 | bioplex_WMM WMM_only |
| MAGED2 | OCIAD1 | 0.004 | 0.008 | bioplex (MAGED2) bioplex_WMM boldt youn_WMM boldt_WMM |
Images
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Complex HuMAP2_00029 has an average edge precision of 0.464 which is ranked 2767 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| GNAS | HuMAP2_00029 HuMAP2_00231 HuMAP2_03216 HuMAP2_04786 HuMAP2_06032 |
| OCIAD1 | HuMAP2_00029 HuMAP2_03216 HuMAP2_06032 |
| MAGED2 | HuMAP2_00029 HuMAP2_00231 HuMAP2_01968 HuMAP2_03216 HuMAP2_04904 |
| GNAL | HuMAP2_00029 HuMAP2_00231 HuMAP2_03216 HuMAP2_04786 HuMAP2_06032 |