hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_00032
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| THOC5 | THO complex subunit 5 homolog (Functional spliceosome-associated protein 79) (fSAP79) (NF2/meningioma region protein pK1.3) (Placental protein 39.2) (PP39.2) (hTREX90) | UniProt NCBI |
| ZC3H11A | Zinc finger CCCH domain-containing protein 11A | UniProt NCBI |
| POLDIP3 | Polymerase delta-interacting protein 3 (46 kDa DNA polymerase delta interaction protein) (p46) (S6K1 Aly/REF-like target) (SKAR) | UniProt NCBI |
| THOC6 | THO complex subunit 6 homolog (Functional spliceosome-associated protein 35) (fSAP35) (WD repeat-containing protein 58) | UniProt NCBI |
| THOC2 | THO complex subunit 2 (Tho2) (hTREX120) | UniProt NCBI |
| THOC7 | THO complex subunit 7 homolog (Functional spliceosome-associated protein 24) (fSAP24) (Ngg1-interacting factor 3-like protein 1-binding protein 1) (NIF3L1-binding protein 1) (hTREX30) | UniProt NCBI |
| THOC1 | THO complex subunit 1 (Tho1) (Nuclear matrix protein p84) (p84N5) (hTREX84) | UniProt NCBI |
| THOC3 | THO complex subunit 3 (Tho3) (TEX1 homolog) (hTREX45) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6160 | 8.55866679422e-20 | 0.75 | THOC2 THOC6 THOC1 THOC7 THOC5 THOC3 | hTREX84 complex |
| CORUM:770 | 5.99037691178e-19 | 0.75 | THOC2 THOC6 THOC1 THOC7 THOC5 THOC3 | TREX complex |
| REAC:R-HSA-72187 | 3.07747843602e-18 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | mRNA 3'-end processing |
| REAC:R-HSA-73856 | 1.14552059564e-17 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | RNA Polymerase II Transcription Termination |
| GO:0000346 | 2.13003926586e-17 | 0.875 | THOC2 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | transcription export complex |
| REAC:R-HSA-159236 | 2.18640063696e-17 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | Transport of Mature mRNA derived from an Intron-Containing Transcript |
| REAC:R-HSA-72202 | 6.22380153697e-17 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | Transport of Mature Transcript to Cytoplasm |
| GO:0000347 | 9.24336013776e-17 | 0.75 | THOC2 THOC6 THOC1 THOC7 THOC5 THOC3 | THO complex |
| GO:0000445 | 9.24336013776e-17 | 0.75 | THOC2 THOC6 THOC1 THOC7 THOC5 THOC3 | THO complex part of transcription export complex |
| CORUM:774 | 4.24766632997e-16 | 0.625 | THOC2 THOC6 THOC1 THOC5 THOC7 | THO complex |
| GO:0046784 | 6.46960706472e-16 | 0.75 | THOC2 THOC6 THOC1 THOC7 THOC5 THOC3 | viral mRNA export from host cell nucleus |
| GO:0051836 | 6.46960706472e-16 | 0.75 | THOC2 THOC6 THOC1 THOC7 THOC5 THOC3 | translocation of molecules into other organism involved in symbiotic interaction |
| GO:0044417 | 6.46960706472e-16 | 0.75 | THOC2 THOC6 THOC1 THOC7 THOC5 THOC3 | translocation of molecules into host |
| GO:0031124 | 8.49455941399e-14 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | mRNA 3'-end processing |
| GO:0006406 | 2.71873482078e-13 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | mRNA export from nucleus |
| GO:0071427 | 2.71873482078e-13 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | mRNA-containing ribonucleoprotein complex export from nucleus |
| GO:0051028 | 3.96605452037e-13 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | mRNA transport |
| REAC:R-HSA-72203 | 6.04901220136e-13 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | Processing of Capped Intron-Containing Pre-mRNA |
| GO:0071426 | 8.0314304909e-13 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | ribonucleoprotein complex export from nucleus |
| GO:0071166 | 8.59013869896e-13 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | ribonucleoprotein complex localization |
| GO:0006405 | 1.44283307754e-12 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | RNA export from nucleus |
| GO:0031123 | 1.73797777074e-12 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | RNA 3'-end processing |
| GO:0050657 | 4.38502186451e-12 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | nucleic acid transport |
| GO:0050658 | 4.38502186451e-12 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | RNA transport |
| GO:0051236 | 5.15723827822e-12 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | establishment of RNA localization |
| GO:0006611 | 6.71029357224e-12 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | protein export from nucleus |
| GO:0051168 | 1.22090159628e-11 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | nuclear export |
| GO:0015931 | 1.40843213462e-11 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | nucleobase-containing compound transport |
| GO:0006403 | 2.54404554643e-11 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | RNA localization |
| GO:0031503 | 1.38257531197e-10 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | protein-containing complex localization |
| GO:0006913 | 4.954169234e-10 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | nucleocytoplasmic transport |
| GO:0051169 | 5.42198892128e-10 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | nuclear transport |
| CORUM:351 | 7.90609834248e-10 | 0.75 | THOC2 THOC6 THOC1 THOC7 THOC5 THOC3 | Spliceosome |
| KEGG:03013 | 1.40972165403e-09 | 0.75 | THOC2 THOC6 THOC1 THOC7 THOC5 THOC3 | RNA transport |
| REAC:R-HSA-8953854 | 2.29458867922e-09 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | Metabolism of RNA |
| GO:0044766 | 1.10004716538e-08 | 0.75 | THOC2 THOC6 THOC1 THOC7 THOC5 THOC3 | multi-organism transport |
| GO:1902579 | 1.10004716538e-08 | 0.75 | THOC2 THOC6 THOC1 THOC7 THOC5 THOC3 | multi-organism localization |
| GO:0006397 | 1.21342588457e-08 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | mRNA processing |
| REAC:R-HSA-73857 | 2.23620488736e-07 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | RNA Polymerase II Transcription |
| GO:0000784 | 3.00666929825e-07 | 0.75 | THOC2 THOC6 THOC1 THOC7 THOC5 THOC3 | nuclear chromosome, telomeric region |
| GO:0051701 | 3.50563837254e-07 | 0.75 | THOC2 THOC6 THOC1 THOC7 THOC5 THOC3 | interaction with host |
| REAC:R-HSA-74160 | 5.36908321467e-07 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | Gene expression (Transcription) |
| GO:0000781 | 8.17359506177e-07 | 0.75 | THOC2 THOC6 THOC1 THOC7 THOC5 THOC3 | chromosome, telomeric region |
| GO:0016071 | 1.32830215932e-06 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | mRNA metabolic process |
| GO:0006396 | 2.51669931039e-06 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | RNA processing |
| GO:0006886 | 1.02082595948e-05 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | intracellular protein transport |
| GO:0098687 | 4.87523213824e-05 | 0.75 | THOC2 THOC6 THOC1 THOC7 THOC5 THOC3 | chromosomal region |
| GO:0015031 | 0.000190092821208 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | protein transport |
| GO:0015833 | 0.000213126626925 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | peptide transport |
| GO:0042886 | 0.00023576916729 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | amide transport |
| GO:0046907 | 0.000346824278428 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | intracellular transport |
| GO:0045184 | 0.000350744550473 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | establishment of protein localization |
| GO:0034613 | 0.000551760175722 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | cellular protein localization |
| GO:0070727 | 0.00057867024204 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | cellular macromolecule localization |
| GO:0071705 | 0.000652723871129 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | nitrogen compound transport |
| GO:0044403 | 0.0014219459486 | 0.75 | THOC2 THOC6 THOC1 THOC7 THOC5 THOC3 | symbiotic process |
| KEGG:03040 | 0.00169432719911 | 0.375 | THOC2 THOC3 THOC1 | Spliceosome |
| GO:0051649 | 0.00181553402649 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | establishment of localization in cell |
| GO:0044419 | 0.00197294951823 | 0.75 | THOC2 THOC6 THOC1 THOC7 THOC5 THOC3 | interspecies interaction between organisms |
| GO:0071702 | 0.00216573094845 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | organic substance transport |
| GO:0016973 | 0.00344619549436 | 0.375 | THOC2 ZC3H11A POLDIP3 | poly(A)+ mRNA export from nucleus |
| GO:0008104 | 0.00449630294969 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | protein localization |
| GO:0033036 | 0.0104943221162 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | macromolecule localization |
| GO:0051641 | 0.0161157357033 | 1.0 | THOC2 POLDIP3 ZC3H11A THOC6 THOC1 THOC7 THOC5 THOC3 | cellular localization |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| THOC1 | THOC6 | 1.0 | 0.949 | hein_WMM youn (THOC1) bioplex (THOC1) bioplex_WMM youn_WMM hein (THOC1) Malo fraction |
| THOC5 | THOC1 | 1.0 | 0.949 | hein_WMM youn (THOC1) bioplex (THOC1) bioplex_WMM youn_WMM hein (THOC1,THOC5) Malo fraction |
| THOC2 | THOC1 | 1.0 | 0.949 | hein_WMM youn (THOC1) bioplex (THOC1) bioplex_WMM youn_WMM hein (THOC1,THOC2) Malo gupta_WMM fraction |
| THOC7 | THOC1 | 1.0 | 0.949 | hein_WMM youn (THOC1) bioplex (THOC1) bioplex_WMM hein (THOC1,THOC7) Malo fraction |
| THOC3 | THOC1 | 1.0 | 0.949 | hein_WMM youn (THOC1) bioplex (THOC1,THOC3) bioplex_WMM youn_WMM hein (THOC1) Malo gupta_WMM fraction |
| THOC7 | THOC5 | 1.0 | 0.949 | hein_WMM bioplex_WMM youn_WMM hein (THOC5,THOC7) Malo fraction |
| THOC2 | THOC7 | 1.0 | 0.949 | hein_WMM bioplex_WMM youn_WMM hein (THOC2,THOC7) Malo gupta_WMM fraction |
| THOC3 | THOC2 | 0.999 | 0.949 | hein_WMM bioplex (THOC3) bioplex_WMM youn_WMM hein (THOC2) Malo gupta_WMM fraction |
| THOC3 | THOC7 | 0.999 | 0.949 | hein_WMM bioplex (THOC3) bioplex_WMM youn_WMM hein (THOC7) Malo fraction |
| THOC3 | THOC5 | 0.999 | 0.948 | hein_WMM bioplex (THOC3) bioplex_WMM youn_WMM hein (THOC5) Malo fraction |
| THOC7 | THOC6 | 0.999 | 0.948 | hein_WMM bioplex_WMM youn_WMM hein (THOC7) Malo fraction |
| THOC5 | THOC6 | 0.998 | 0.939 | hein_WMM bioplex_WMM Guru youn_WMM hein (THOC5) Malo fraction |
| THOC2 | THOC6 | 0.993 | 0.918 | hein_WMM bioplex_WMM youn_WMM hein (THOC2) Malo fraction |
| THOC2 | THOC5 | 0.988 | 0.902 | hein_WMM bioplex_WMM youn_WMM hein (THOC2,THOC5) Malo fraction |
| ZC3H11A | THOC1 | 0.886 | 0.817 | hein_WMM youn (THOC1) bioplex_WMM youn_WMM hein (THOC1) |
| THOC3 | THOC6 | 0.866 | 0.801 | hein_WMM bioplex (THOC3) bioplex_WMM youn_WMM Malo fraction |
| THOC2 | POLDIP3 | 0.602 | 0.671 | hein_WMM bioplex_WMM youn_WMM hein (THOC2) gupta_WMM |
| THOC2 | ZC3H11A | 0.312 | 0.505 | hein_WMM bioplex_WMM youn_WMM hein (THOC2) gupta_WMM |
| THOC7 | POLDIP3 | 0.262 | 0.482 | hein_WMM youn_WMM hein (THOC7) |
| THOC5 | POLDIP3 | 0.25 | 0.473 | hein_WMM bioplex_WMM youn_WMM hein (THOC5) |
| THOC1 | POLDIP3 | 0.235 | 0.47 | hein_WMM youn (THOC1) bioplex_WMM youn_WMM hein (THOC1) gupta_WMM |
| THOC5 | ZC3H11A | 0.11 | 0.379 | hein_WMM bioplex_WMM youn_WMM hein (THOC5) |
| THOC7 | ZC3H11A | 0.079 | 0.352 | hein_WMM youn_WMM hein (THOC7) |
| ZC3H11A | THOC6 | 0.012 | 0.149 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| THOC3 | ZC3H11A | 0.011 | 0.145 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| ZC3H11A | POLDIP3 | 0.011 | 0.14 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| THOC3 | POLDIP3 | 0.01 | 0.13 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| POLDIP3 | THOC6 | 0.009 | 0.09 | hein_WMM bioplex_WMM youn_WMM WMM_only |
Images
Click to enlarge
Complex HuMAP2_00032 has an average edge precision of 0.671 which is ranked 1512 out of all 6965 complexes.
Related Complexes