hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00045
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CDK11B | Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1) | UniProt NCBI |
| CDK11A | Cyclin-dependent kinase 11A (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 2) (Cell division protein kinase 11A) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L2) | UniProt NCBI |
| SAP30BP | SAP30-binding protein (Transcriptional regulator protein HCNGP) | UniProt NCBI |
| HTATSF1 | HIV Tat-specific factor 1 (Tat-SF1) | UniProt NCBI |
| TCOF1 | Treacle protein (Treacher Collins syndrome protein) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| TF:M08271_1 | 0.0270421395626 | 0.4 | CDK11A CDK11B | Factor: Erm:TBR2; motif: NNGTGNKANNNNNNNNTNNCRSCGGAWGN; match class: 1 |
| REAC:R-HSA-380287 | 0.0411580285567 | 0.4 | CDK11A CDK11B | Centrosome maturation |
| REAC:R-HSA-380270 | 0.0411580285567 | 0.4 | CDK11A CDK11B | Recruitment of mitotic centrosome proteins and complexes |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CDK11A | HTATSF1 | 0.564 | 0.651 | boldt youn_WMM fraction boldt_WMM |
| CDK11A | SAP30BP | 0.529 | 0.634 | bioplex (CDK11A) bioplex_WMM Guru boldt youn_WMM Malo fraction boldt_WMM |
| HTATSF1 | TCOF1 | 0.386 | 0.551 | bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM |
| HTATSF1 | SAP30BP | 0.033 | 0.247 | bioplex_WMM boldt youn_WMM fraction boldt_WMM |
| CDK11A | CDK11B | 0.027 | 0.232 | youn_WMM bioplex () bioplex_WMM |
| CDK11A | TCOF1 | 0.027 | 0.225 | boldt youn_WMM gupta_WMM fraction boldt_WMM |
| TCOF1 | SAP30BP | 0.025 | 0.211 | bioplex_WMM youn_WMM fraction |
| HTATSF1 | CDK11B | 0.007 | 0.005 | bioplex_WMM youn_WMM WMM_only |
| TCOF1 | CDK11B | 0.007 | 0.003 | bioplex_WMM youn_WMM WMM_only |
| CDK11B | SAP30BP | 0.007 | 0.003 | bioplex_WMM youn_WMM WMM_only |
Images
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Complex HuMAP2_00045 has an average edge precision of 0.276 which is ranked 4937 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CDK11B | HuMAP2_00045 HuMAP2_02300 HuMAP2_05740 HuMAP2_06272 |
| CDK11A | HuMAP2_00045 HuMAP2_01780 HuMAP2_03179 HuMAP2_04784 HuMAP2_06498 |
| SAP30BP | HuMAP2_00045 HuMAP2_03179 HuMAP2_06498 |
| HTATSF1 | HuMAP2_00045 HuMAP2_03369 HuMAP2_06498 |
| TCOF1 | HuMAP2_00045 HuMAP2_00404 HuMAP2_06370 |