hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_00048
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ZNRF2 | E3 ubiquitin-protein ligase ZNRF2 (EC 2.3.2.27) (Protein Ells2) (RING finger protein 202) (RING-type E3 ubiquitin transferase ZNRF2) (Zinc/RING finger protein 2) | UniProt NCBI |
| ADHFE1 | Hydroxyacid-oxoacid transhydrogenase, mitochondrial (HOT) (EC 1.1.99.24) (Alcohol dehydrogenase iron-containing protein 1) (ADHFe1) (Fe-containing alcohol dehydrogenase) | UniProt NCBI |
| RPIA | Ribose-5-phosphate isomerase (EC 5.3.1.6) (Phosphoriboisomerase) | UniProt NCBI |
| NPEPL1 | Probable aminopeptidase NPEPL1 (EC 3.4.11.-) (Aminopeptidase-like 1) | UniProt NCBI |
| ACMSD | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (EC 4.1.1.45) (Picolinate carboxylase) | UniProt NCBI |
| WDR5B | WD repeat-containing protein 5B | UniProt NCBI |
| YJEFN3 | YjeF N-terminal domain-containing protein 3 (YjeF_N3) (hYjeF_N3) | UniProt NCBI |
| DHH | Desert hedgehog protein (DHH) (HHG-3) [Cleaved into: Desert hedgehog protein N-product; Desert hedgehog protein C-product] | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ZNRF2 | WDR5B | 0.697 | 0.718 | bioplex (WDR5B) bioplex_WMM |
| WDR5B | RPIA | 0.321 | 0.512 | bioplex (WDR5B) bioplex_WMM |
| RPIA | NPEPL1 | 0.133 | 0.405 | Guru fraction |
| ADHFE1 | NPEPL1 | 0.053 | 0.301 | fraction |
| DHH | RPIA | 0.049 | 0.294 | bioplex (DHH) bioplex_WMM |
| ACMSD | NPEPL1 | 0.046 | 0.293 | fraction |
| ADHFE1 | RPIA | 0.039 | 0.264 | fraction |
| ACMSD | YJEFN3 | 0.031 | 0.238 | fraction |
| ZNRF2 | RPIA | 0.008 | 0.066 | bioplex_WMM WMM_only |
Images
Click to enlarge
Complex HuMAP2_00048 has an average edge precision of 0.343 which is ranked 4080 out of all 6965 complexes.
Related Complexes