hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00053
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NT5DC1 | 5'-nucleotidase domain-containing protein 1 (EC 3.1.3.-) | UniProt NCBI |
| GALK2 | N-acetylgalactosamine kinase (EC 2.7.1.157) (GalNAc kinase) (Galactokinase 2) | UniProt NCBI |
| LTA4H | Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase) | UniProt NCBI |
| PITPNA | Phosphatidylinositol transfer protein alpha isoform (PI-TP-alpha) (PtdIns transfer protein alpha) (PtdInsTP alpha) | UniProt NCBI |
| HEXB | Beta-hexosaminidase subunit beta (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit beta) (Hexosaminidase subunit B) (Cervical cancer proto-oncogene 7 protein) (HCC-7) (N-acetyl-beta-glucosaminidase subunit beta) [Cleaved into: Beta-hexosaminidase subunit beta chain B; Beta-hexosaminidase subunit beta chain A] | UniProt NCBI |
| PGP | Glycerol-3-phosphate phosphatase (G3PP) (EC 3.1.3.21) (Aspartate-based ubiquitous Mg(2+)-dependent phosphatase) (AUM) (EC 3.1.3.48) (Phosphoglycolate phosphatase) (PGP) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6275 | 0.0249904952816 | 0.166666666667 | HEXB | HEXB homodimer complex |
| CORUM:6274 | 0.0499726005494 | 0.166666666667 | HEXB | HEXA-HEXB complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NT5DC1 | PGP | 0.512 | 0.631 | bioplex_WMM fraction |
| LTA4H | NT5DC1 | 0.508 | 0.628 | bioplex_WMM fraction |
| LTA4H | PGP | 0.374 | 0.546 | bioplex_WMM fraction |
| LTA4H | PITPNA | 0.045 | 0.284 | bioplex_WMM fraction |
| GALK2 | PGP | 0.045 | 0.283 | fraction |
| LTA4H | HEXB | 0.041 | 0.27 | bioplex_WMM fraction |
| PITPNA | PGP | 0.01 | 0.116 | bioplex_WMM fraction |
| PITPNA | HEXB | 0.006 | 0.003 | bioplex_WMM WMM_only |
| HEXB | PGP | 0.005 | 0.007 | bioplex_WMM WMM_only |
| GALK2 | LTA4H | 0.005 | 0.012 | fraction |
| NT5DC1 | HEXB | 0.004 | 0.009 | bioplex (NT5DC1) bioplex_WMM |
| PITPNA | NT5DC1 | 0.003 | 0.011 | bioplex_WMM WMM_only |
| GALK2 | PITPNA | 0.0 | 0.012 | fraction |
Images
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Complex HuMAP2_00053 has an average edge precision of 0.216 which is ranked 5922 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NT5DC1 | HuMAP2_00053 HuMAP2_02627 HuMAP2_02765 HuMAP2_05050 HuMAP2_05233 |
| GALK2 | HuMAP2_00053 HuMAP2_00790 HuMAP2_02894 HuMAP2_03534 HuMAP2_04046 HuMAP2_04356 |
| LTA4H | HuMAP2_00053 HuMAP2_02765 HuMAP2_03790 |
| PITPNA | HuMAP2_00053 HuMAP2_01352 HuMAP2_04441 HuMAP2_05192 |
| HEXB | HuMAP2_00053 HuMAP2_00675 HuMAP2_05194 HuMAP2_05271 |
| PGP | HuMAP2_00053 HuMAP2_02627 HuMAP2_02765 HuMAP2_05050 |