hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00055
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| EIF4A1 | Eukaryotic initiation factor 4A-I (eIF-4A-I) (eIF4A-I) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-1) | UniProt NCBI |
| EIF4G2 | Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (Death-associated protein 5) (DAP-5) (p97) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:03013 | 0.00169649664321 | 1.0 | EIF4A1 EIF4G2 | RNA transport |
| REAC:R-HSA-1169408 | 0.00370546677531 | 1.0 | EIF4A1 EIF4G2 | ISG15 antiviral mechanism |
| REAC:R-HSA-1169410 | 0.00452666927187 | 1.0 | EIF4A1 EIF4G2 | Antiviral mechanism by IFN-stimulated genes |
| GO:0016281 | 0.0247952876258 | 1.0 | EIF4A1 EIF4G2 | eukaryotic translation initiation factor 4F complex |
| REAC:R-HSA-913531 | 0.0252243240322 | 1.0 | EIF4A1 EIF4G2 | Interferon Signaling |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| EIF4A1 | EIF4G2 | 0.718 | 0.73 | hein_WMM youn (EIF4A1) bioplex (EIF4A1) bioplex_WMM boldt youn_WMM fraction boldt_WMM treiber_WMM |
Images
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Complex HuMAP2_00055 has an average edge precision of 0.73 which is ranked 1257 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| EIF4A1 | HuMAP2_00055 HuMAP2_03421 HuMAP2_04458 HuMAP2_05935 |
| EIF4G2 | HuMAP2_00055 HuMAP2_03421 HuMAP2_05935 |