hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00058
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| FAM160A2 | FTS and Hook-interacting protein (FHIP) (Protein FAM160A2) | UniProt NCBI |
| AKTIP | AKT-interacting protein (Ft1) (Fused toes protein homolog) | UniProt NCBI |
| NAB2 | NGFI-A-binding protein 2 (EGR-1-binding protein 2) (Melanoma-associated delayed early response protein) (Protein MADER) | UniProt NCBI |
| CTIF | CBP80/20-dependent translation initiation factor | UniProt NCBI |
| NAB1 | NGFI-A-binding protein 1 (EGR-1-binding protein 1) (Transcriptional regulatory protein p54) | UniProt NCBI |
| HOOK1 | Protein Hook homolog 1 (h-hook1) (hHK1) | UniProt NCBI |
| HOOK3 | Protein Hook homolog 3 (h-hook3) (hHK3) | UniProt NCBI |
| FAM160A1 | Protein FAM160A1 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6109 | 7.90426989013e-12 | 0.5 | AKTIP HOOK3 FAM160A2 HOOK1 | FHF complex |
| GO:0070695 | 8.53661148134e-09 | 0.5 | AKTIP HOOK3 FAM160A2 HOOK1 | FHF complex |
| GO:0045022 | 0.000111986618346 | 0.5 | AKTIP HOOK3 FAM160A2 HOOK1 | early endosome to late endosome transport |
| GO:0098927 | 0.00013940565471 | 0.5 | AKTIP HOOK3 FAM160A2 HOOK1 | vesicle-mediated transport between endosomal compartments |
| GO:0008333 | 0.000189585536071 | 0.5 | AKTIP HOOK3 FAM160A2 HOOK1 | endosome to lysosome transport |
| GO:0080171 | 0.00025220276615 | 0.5 | AKTIP HOOK3 FAM160A2 HOOK1 | lytic vacuole organization |
| GO:0007040 | 0.00025220276615 | 0.5 | AKTIP HOOK3 FAM160A2 HOOK1 | lysosome organization |
| GO:0030897 | 0.00111635111712 | 0.375 | AKTIP HOOK3 HOOK1 | HOPS complex |
| GO:0007032 | 0.0015436837415 | 0.5 | AKTIP HOOK3 FAM160A2 HOOK1 | endosome organization |
| GO:0007041 | 0.00391075575532 | 0.5 | AKTIP HOOK3 FAM160A2 HOOK1 | lysosomal transport |
| GO:0007034 | 0.0103621822618 | 0.5 | AKTIP HOOK3 FAM160A2 HOOK1 | vacuolar transport |
| GO:0007033 | 0.0194680313645 | 0.5 | AKTIP HOOK3 FAM160A2 HOOK1 | vacuole organization |
| GO:0016482 | 0.0276791086381 | 0.5 | AKTIP HOOK3 FAM160A2 HOOK1 | cytosolic transport |
| CORUM:6126 | 0.0497224828424 | 0.125 | AKTIP | FTS-Vps41 complex |
| CORUM:6116 | 0.0497224828424 | 0.125 | HOOK1 | Hook1-Vps16 complex |
| CORUM:6117 | 0.0497224828424 | 0.125 | HOOK1 | Hook1-Vps18 complex |
| CORUM:6118 | 0.0497224828424 | 0.125 | HOOK1 | Hook1-Vps39 complex |
| CORUM:6119 | 0.0497224828424 | 0.125 | HOOK1 | Hook1-Vps41 complex |
| CORUM:6122 | 0.0497224828424 | 0.125 | HOOK3 | Hook3-Vps16 complex |
| CORUM:6123 | 0.0497224828424 | 0.125 | HOOK3 | Hook3-Vps41 complex |
| CORUM:6124 | 0.0497224828424 | 0.125 | AKTIP | FTS-Vps16 complex |
| CORUM:6125 | 0.0497224828424 | 0.125 | AKTIP | FTS-Vps18 complex |
| CORUM:7441 | 0.0497224828424 | 0.125 | HOOK1 | HOOK1-SHP2 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| AKTIP | FAM160A2 | 1.0 | 0.949 | bioplex (AKTIP) bioplex_WMM youn_WMM |
| AKTIP | FAM160A1 | 1.0 | 0.949 | bioplex (AKTIP) bioplex_WMM youn_WMM |
| AKTIP | HOOK3 | 0.999 | 0.949 | bioplex (AKTIP,HOOK3) bioplex_WMM youn_WMM gupta_WMM |
| AKTIP | HOOK1 | 0.989 | 0.904 | bioplex (AKTIP) bioplex_WMM youn_WMM |
| HOOK3 | FAM160A2 | 0.887 | 0.818 | bioplex (HOOK3) bioplex_WMM youn_WMM |
| AKTIP | NAB1 | 0.344 | 0.533 | bioplex (AKTIP) bioplex_WMM |
| HOOK3 | FAM160A1 | 0.241 | 0.468 | bioplex (HOOK3) bioplex_WMM youn_WMM |
| CTIF | HOOK1 | 0.177 | 0.435 | youn (CTIF) youn_WMM |
| NAB1 | NAB2 | 0.114 | 0.383 | bioplex (NAB2) bioplex_WMM |
| CTIF | HOOK3 | 0.09 | 0.354 | youn (CTIF) youn_WMM |
| HOOK1 | HOOK3 | 0.025 | 0.215 | bioplex (HOOK3) bioplex_WMM youn_WMM gupta_WMM fraction |
| FAM160A1 | FAM160A2 | 0.012 | 0.149 | bioplex_WMM youn_WMM WMM_only |
| HOOK1 | FAM160A2 | 0.011 | 0.145 | bioplex_WMM youn_WMM WMM_only |
| HOOK1 | FAM160A1 | 0.01 | 0.112 | bioplex_WMM youn_WMM WMM_only |
| AKTIP | CTIF | 0.009 | 0.107 | youn (CTIF) youn_WMM |
| NAB1 | FAM160A1 | 0.009 | 0.092 | bioplex_WMM WMM_only |
| NAB1 | FAM160A2 | 0.009 | 0.096 | bioplex_WMM WMM_only |
| NAB1 | HOOK3 | 0.008 | 0.082 | bioplex_WMM WMM_only |
| NAB1 | HOOK1 | 0.008 | 0.027 | bioplex_WMM WMM_only |
| CTIF | FAM160A2 | 0.005 | 0.007 | youn (CTIF) youn_WMM |
| CTIF | FAM160A1 | 0.005 | 0.009 | youn (CTIF) youn_WMM |
Images
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Complex HuMAP2_00058 has an average edge precision of 0.371 which is ranked 3635 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| FAM160A2 | HuMAP2_00058 HuMAP2_03893 HuMAP2_05370 |
| AKTIP | HuMAP2_00058 HuMAP2_03373 HuMAP2_03893 HuMAP2_05370 |
| NAB2 | HuMAP2_00058 HuMAP2_01143 HuMAP2_05370 |
| CTIF | HuMAP2_00058 HuMAP2_04216 HuMAP2_04774 HuMAP2_06146 HuMAP2_06247 |
| NAB1 | HuMAP2_00058 HuMAP2_01143 HuMAP2_03373 HuMAP2_05370 |
| HOOK1 | HuMAP2_00058 HuMAP2_03373 HuMAP2_03893 HuMAP2_05370 HuMAP2_06146 |
| HOOK3 | HuMAP2_00058 HuMAP2_03373 HuMAP2_03893 HuMAP2_05370 |
| FAM160A1 | HuMAP2_00058 HuMAP2_03373 HuMAP2_03893 HuMAP2_05370 |