hu.MAP 2.0: Complex View

Human Protein Complex Map

Complex: HuMAP2_00092

Confidence: Medium

Genename	Protein Name	Links
SLC1A3	Excitatory amino acid transporter 1 (Sodium-dependent glutamate/aspartate transporter 1) (GLAST-1) (Solute carrier family 1 member 3)	UniProt NCBI
TMEM45A	Transmembrane protein 45A (DNA polymerase-transactivated protein 4) (Dermal papilla-derived protein 7)	UniProt NCBI
DHX37	Probable ATP-dependent RNA helicase DHX37 (EC 3.6.4.13) (DEAH box protein 37)	UniProt NCBI
TFAM	Transcription factor A, mitochondrial (mtTFA) (Mitochondrial transcription factor 1) (MtTF1) (Transcription factor 6) (TCF-6) (Transcription factor 6-like 2)	UniProt NCBI
PDPK1	3-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)	UniProt NCBI
KCTD2	BTB/POZ domain-containing protein KCTD2 (Potassium channel tetramerization domain-containing protein 2)	UniProt NCBI
POLK	DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP)	UniProt NCBI
FAM89A	Protein FAM89A	UniProt NCBI
CDC42BPA	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (DMPK-like alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha)	UniProt NCBI
THAP9	DNA transposase THAP9 (EC 2.7.7.-) (THAP domain-containing protein 9) (hTh9)	UniProt NCBI
KCTD5	BTB/POZ domain-containing protein KCTD5	UniProt NCBI
KCTD17	BTB/POZ domain-containing protein KCTD17	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0097602	0.0135004782501	0.25	KCTD5 KCTD2 KCTD17	cullin family protein binding
KEGG:05213	0.0421208202383	0.166666666667	POLK PDPK1	Endometrial cancer

Edges

Protein 1	Protein 2	Score	Precision	Evidence
KCTD5	KCTD17	0.992	0.911	bioplex (KCTD17) bioplex_WMM boldt_WMM
KCTD2	KCTD17	0.991	0.909	bioplex (KCTD17) bioplex_WMM
KCTD2	KCTD5	0.572	0.655	hein_WMM bioplex_WMM hein (KCTD5)
FAM89A	KCTD17	0.241	0.468	bioplex (KCTD17) bioplex_WMM
TMEM45A	KCTD5	0.153	0.411	hein_WMM hein (KCTD5)
POLK	KCTD17	0.15	0.41	bioplex (KCTD17) bioplex_WMM
PDPK1	KCTD5	0.116	0.389	hein_WMM hein (KCTD5)
THAP9	KCTD17	0.103	0.366	bioplex (KCTD17) bioplex_WMM
CDC42BPA	KCTD17	0.094	0.358	bioplex (KCTD17) bioplex_WMM
SLC1A3	KCTD5	0.067	0.351	hein_WMM bioplex_WMM hein (KCTD5)
POLK	KCTD5	0.052	0.299	hein_WMM bioplex_WMM hein (KCTD5,POLK)
PDPK1	DHX37	0.043	0.269	fraction
TFAM	KCTD17	0.026	0.219	bioplex (KCTD17) bioplex_WMM
THAP9	KCTD5	0.021	0.192	hein_WMM bioplex_WMM hein (KCTD5)
THAP9	POLK	0.009	0.112	hein_WMM bioplex_WMM WMM_only
THAP9	FAM89A	0.009	0.108	bioplex_WMM WMM_only
THAP9	CDC42BPA	0.009	0.096	bioplex_WMM WMM_only
THAP9	KCTD2	0.009	0.098	hein_WMM bioplex_WMM WMM_only
POLK	FAM89A	0.008	0.091	bioplex_WMM WMM_only
FAM89A	CDC42BPA	0.008	0.085	bioplex_WMM WMM_only
TMEM45A	SLC1A3	0.008	0.083	hein_WMM WMM_only
THAP9	SLC1A3	0.008	0.082	hein_WMM bioplex_WMM WMM_only
POLK	CDC42BPA	0.008	0.069	bioplex_WMM WMM_only
KCTD2	POLK	0.008	0.066	hein_WMM bioplex_WMM WMM_only
PDPK1	TMEM45A	0.008	0.062	hein_WMM WMM_only
PDPK1	SLC1A3	0.008	0.062	hein_WMM WMM_only
KCTD2	FAM89A	0.008	0.061	bioplex_WMM WMM_only
KCTD5	FAM89A	0.008	0.042	bioplex_WMM WMM_only
TMEM45A	POLK	0.008	0.034	hein_WMM WMM_only
THAP9	TMEM45A	0.008	0.034	hein_WMM WMM_only
THAP9	TFAM	0.008	0.029	bioplex_WMM WMM_only
POLK	SLC1A3	0.008	0.025	hein_WMM bioplex_WMM WMM_only
TMEM45A	KCTD2	0.008	0.024	hein_WMM WMM_only
KCTD2	CDC42BPA	0.008	0.011	bioplex_WMM WMM_only
THAP9	PDPK1	0.008	0.012	hein_WMM WMM_only
PDPK1	POLK	0.008	0.012	hein_WMM WMM_only
KCTD5	CDC42BPA	0.007	0.006	bioplex_WMM WMM_only
TFAM	FAM89A	0.007	0.003	bioplex_WMM WMM_only
PDPK1	KCTD2	0.007	0.01	hein_WMM WMM_only
POLK	TFAM	0.007	0.006	bioplex_WMM WMM_only
DHX37	TFAM	0.007	0.006	bioplex_WMM youn_WMM WMM_only
PDPK1	TFAM	0.007	0.003	bioplex_WMM youn_WMM WMM_only
SLC1A3	FAM89A	0.007	0.004	bioplex_WMM WMM_only
SLC1A3	DHX37	0.007	0.005	bioplex_WMM youn_WMM WMM_only
TFAM	CDC42BPA	0.007	0.002	bioplex_WMM WMM_only
DHX37	CDC42BPA	0.007	0.0	bioplex_WMM WMM_only
DHX37	KCTD5	0.007	0.003	bioplex_WMM WMM_only
KCTD2	SLC1A3	0.007	0.005	hein_WMM bioplex_WMM WMM_only
SLC1A3	CDC42BPA	0.007	0.004	bioplex_WMM WMM_only
KCTD2	TFAM	0.007	0.005	bioplex_WMM WMM_only
KCTD5	TFAM	0.007	0.004	bioplex_WMM WMM_only
SLC1A3	TFAM	0.006	0.004	bioplex_WMM WMM_only
SLC1A3	KCTD17	0.006	0.007	bioplex (KCTD17) bioplex_WMM
POLK	DHX37	0.003	0.007	youn_WMM fraction

Images

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Complex HuMAP2_00092 has an average edge precision of 0.141 which is ranked 6768 out of all 6965 complexes.

Related Complexes

Genename	Complexes
SLC1A3	HuMAP2_00092 HuMAP2_00181 HuMAP2_01814 HuMAP2_02264 HuMAP2_04397
TMEM45A	HuMAP2_00092 HuMAP2_00181 HuMAP2_01814 HuMAP2_02264
DHX37	HuMAP2_00092 HuMAP2_00610 HuMAP2_04614
TFAM	HuMAP2_00092 HuMAP2_03648
PDPK1	HuMAP2_00092 HuMAP2_00181 HuMAP2_04614
KCTD2	HuMAP2_00092 HuMAP2_00181 HuMAP2_01814 HuMAP2_02264 HuMAP2_04307
POLK	HuMAP2_00092 HuMAP2_02264 HuMAP2_03143 HuMAP2_03627 HuMAP2_06193
FAM89A	HuMAP2_00092 HuMAP2_00156 HuMAP2_01818 HuMAP2_03304 HuMAP2_04119 HuMAP2_05085 HuMAP2_05377 HuMAP2_06406
CDC42BPA	HuMAP2_00092 HuMAP2_00431 HuMAP2_06422
THAP9	HuMAP2_00092 HuMAP2_03304 HuMAP2_06182 HuMAP2_07015
KCTD5	HuMAP2_00092 HuMAP2_00181 HuMAP2_01814 HuMAP2_02264 HuMAP2_04307
KCTD17	HuMAP2_00092 HuMAP2_00181 HuMAP2_02264 HuMAP2_03304 HuMAP2_04307

hu.MAP 2.0: Complex View

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Complex: HuMAP2_00092