hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00095
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TRIM27 | Zinc finger protein RFP (EC 2.3.2.27) (RING finger protein 76) (RING-type E3 ubiquitin transferase TRIM27) (Ret finger protein) (Tripartite motif-containing protein 27) | UniProt NCBI |
| USP7 | Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) | UniProt NCBI |
| ZNF609 | Zinc finger protein 609 | UniProt NCBI |
| ACTL8 | Actin-like protein 8 (Cancer/testis antigen 57) (CT57) | UniProt NCBI |
| SCML2 | Sex comb on midleg-like protein 2 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6136 | 6.70868171695e-06 | 0.4 | USP7 TRIM27 | USP7-MAGEL2-TRIM27 complex |
| CORUM:7421 | 0.0249780992026 | 0.2 | USP7 | TSPY1-TSPYL5-USP7 complex |
| CORUM:5663 | 0.0499494897235 | 0.2 | TRIM27 | TRIM27-RB1 complex |
| CORUM:7420 | 0.0499494897235 | 0.2 | USP7 | TP53-TSPY1-USP7 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| USP7 | ACTL8 | 0.179 | 0.438 | hein_WMM hein (USP7) |
| USP7 | SCML2 | 0.135 | 0.407 | hein_WMM bioplex_WMM youn_WMM hein (USP7) gupta_WMM fraction |
| USP7 | TRIM27 | 0.071 | 0.352 | hein_WMM bioplex (TRIM27) bioplex_WMM youn_WMM hein (USP7) gupta_WMM fraction |
| USP7 | ZNF609 | 0.022 | 0.199 | hein_WMM youn_WMM hein (USP7) gupta_WMM |
| ZNF609 | SCML2 | 0.007 | 0.007 | hein_WMM youn_WMM WMM_only |
| TRIM27 | SCML2 | 0.006 | 0.004 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| ACTL8 | ZNF609 | 0.006 | 0.003 | hein_WMM WMM_only |
| ACTL8 | SCML2 | 0.006 | 0.002 | hein_WMM WMM_only |
| ZNF609 | TRIM27 | 0.006 | 0.008 | hein_WMM boldt youn_WMM boldt_WMM |
| ACTL8 | TRIM27 | 0.004 | 0.011 | hein_WMM WMM_only |
Images
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Complex HuMAP2_00095 has an average edge precision of 0.143 which is ranked 6753 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| TRIM27 | HuMAP2_00095 HuMAP2_03772 HuMAP2_06142 |
| USP7 | HuMAP2_00095 |
| ZNF609 | HuMAP2_00095 HuMAP2_03332 |
| ACTL8 | HuMAP2_00095 HuMAP2_02465 |
| SCML2 | HuMAP2_00095 HuMAP2_02083 |