hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00096
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RTCB | tRNA-splicing ligase RtcB homolog (EC 6.5.1.3) | UniProt NCBI |
| HNRNPM | Heterogeneous nuclear ribonucleoprotein M (hnRNP M) | UniProt NCBI |
| PSPC1 | Paraspeckle component 1 (Paraspeckle protein 1) | UniProt NCBI |
| TPR | Nucleoprotein TPR (Megator) (NPC-associated intranuclear protein) (Translocated promoter region protein) | UniProt NCBI |
| DDX1 | ATP-dependent RNA helicase DDX1 (EC 3.6.4.13) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6301 | 6.7059790554e-05 | 0.4 | DDX1 RTCB | tRNA Splicing Ligase Complex |
| REAC:R-HSA-6784531 | 6.70990066737e-05 | 0.6 | DDX1 TPR RTCB | tRNA processing in the nucleus |
| REAC:R-HSA-72306 | 0.000462229124052 | 0.6 | DDX1 TPR RTCB | tRNA processing |
| CORUM:1332 | 0.00127157081923 | 0.4 | DDX1 HNRNPM | Large Drosha complex |
| REAC:R-HSA-8953854 | 0.00262978456954 | 0.8 | DDX1 HNRNPM TPR RTCB | Metabolism of RNA |
| WP:WP411 | 0.0254557044772 | 0.4 | DDX1 HNRNPM | mRNA Processing |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DDX1 | RTCB | 1.0 | 0.949 | hein_WMM youn (DDX1) bioplex_WMM boldt youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| TPR | DDX1 | 0.982 | 0.897 | youn (DDX1) bioplex_WMM youn_WMM gupta_WMM fraction |
| RTCB | HNRNPM | 0.723 | 0.733 | bioplex_WMM boldt fraction boldt_WMM treiber_WMM |
| DDX1 | HNRNPM | 0.579 | 0.661 | hein_WMM youn (DDX1) bioplex_WMM boldt fraction boldt_WMM treiber_WMM |
| DDX1 | PSPC1 | 0.526 | 0.634 | hein_WMM youn (DDX1) bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| PSPC1 | HNRNPM | 0.342 | 0.53 | bioplex_WMM boldt fraction boldt_WMM treiber_WMM |
| TPR | HNRNPM | 0.053 | 0.301 | bioplex_WMM fraction treiber_WMM |
| PSPC1 | RTCB | 0.029 | 0.231 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| TPR | RTCB | 0.007 | 0.006 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| TPR | PSPC1 | 0.004 | 0.01 | bioplex_WMM youn_WMM gupta_WMM fraction |
Images
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Complex HuMAP2_00096 has an average edge precision of 0.495 which is ranked 2527 out of all 6965 complexes.
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