hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_00111
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DDAH2 | N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 (DDAH-2) (Dimethylarginine dimethylaminohydrolase 2) (EC 3.5.3.18) (DDAHII) (Dimethylargininase-2) (Protein G6a) (S-phase protein) | UniProt NCBI |
| DDAH1 | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (DDAH-1) (Dimethylarginine dimethylaminohydrolase 1) (EC 3.5.3.18) (DDAHI) (Dimethylargininase-1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-203615 | 7.54165558069e-05 | 1.0 | DDAH1 DDAH2 | eNOS activation |
| REAC:R-HSA-202131 | 0.000152509035076 | 1.0 | DDAH1 DDAH2 | Metabolism of nitric oxide: eNOS activation and regulation |
| GO:0016403 | 0.000450823411379 | 1.0 | DDAH1 DDAH2 | dimethylargininase activity |
| GO:0016813 | 0.0126230555186 | 1.0 | DDAH1 DDAH2 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines |
| GO:0000052 | 0.0126230555186 | 1.0 | DDAH1 DDAH2 | citrulline metabolic process |
| GO:0006527 | 0.020287053512 | 1.0 | DDAH1 DDAH2 | arginine catabolic process |
| GO:0006525 | 0.0473364581948 | 1.0 | DDAH1 DDAH2 | arginine metabolic process |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DDAH1 | DDAH2 | 0.997 | 0.934 | bioplex (DDAH2) bioplex_WMM |
Images
Click to enlarge
Complex HuMAP2_00111 has an average edge precision of 0.934 which is ranked 420 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DDAH2 | HuMAP2_00111 HuMAP2_02844 HuMAP2_06471 |
| DDAH1 | HuMAP2_00111 HuMAP2_02844 HuMAP2_06471 HuMAP2_06892 |