hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00116
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RAB6A | Ras-related protein Rab-6A (Rab-6) | UniProt NCBI |
| RAB6B | Ras-related protein Rab-6B | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8854214 | 0.00151335888652 | 1.0 | RAB6A RAB6B | TBC/RABGAPs |
| REAC:R-HSA-6811440 | 0.00181167326283 | 1.0 | RAB6A RAB6B | Retrograde transport at the Trans-Golgi-Network |
| REAC:R-HSA-6811436 | 0.00205300624141 | 1.0 | RAB6A RAB6B | COPI-independent Golgi-to-ER retrograde traffic |
| REAC:R-HSA-8873719 | 0.00316917126735 | 1.0 | RAB6A RAB6B | RAB geranylgeranylation |
| REAC:R-HSA-8876198 | 0.00598304676068 | 1.0 | RAB6A RAB6B | RAB GEFs exchange GTP for GDP on RABs |
| REAC:R-HSA-9007101 | 0.011178409494 | 1.0 | RAB6A RAB6B | Rab regulation of trafficking |
| REAC:R-HSA-8856688 | 0.014052618232 | 1.0 | RAB6A RAB6B | Golgi-to-ER retrograde transport |
| REAC:R-HSA-6811442 | 0.0323553783646 | 1.0 | RAB6A RAB6B | Intra-Golgi and retrograde Golgi-to-ER traffic |
| GO:0031489 | 0.0410249304355 | 1.0 | RAB6A RAB6B | myosin V binding |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RAB6A | RAB6B | 0.743 | 0.739 | bioplex (RAB6B) bioplex_WMM treiber_WMM |
Images
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Complex HuMAP2_00116 has an average edge precision of 0.739 which is ranked 1208 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RAB6A | HuMAP2_00116 HuMAP2_01634 |
| RAB6B | HuMAP2_00116 HuMAP2_01634 HuMAP2_03796 HuMAP2_04163 |