hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00121
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| UBL3 | Ubiquitin-like protein 3 (Membrane-anchored ubiquitin-fold protein) (HsMUB) (MUB) (Protein HCG-1) | UniProt NCBI |
| FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase subunit alpha) (FTase-alpha) (Ras proteins prenyltransferase subunit alpha) (Type I protein geranyl-geranyltransferase subunit alpha) (GGTase-I-alpha) | UniProt NCBI |
| GRIP1 | Glutamate receptor-interacting protein 1 (GRIP-1) | UniProt NCBI |
| FNTB | Protein farnesyltransferase subunit beta (FTase-beta) (EC 2.5.1.58) (CAAX farnesyltransferase subunit beta) (Ras proteins prenyltransferase subunit beta) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:419 | 5.02777038712e-06 | 0.5 | FNTA FNTB | Farnesyltransferase |
| KEGG:00900 | 0.000462016961981 | 0.5 | FNTA FNTB | Terpenoid backbone biosynthesis |
| REAC:R-HSA-2514859 | 0.0019074750117 | 0.5 | FNTA FNTB | Inactivation, recovery and regulation of the phototransduction cascade |
| REAC:R-HSA-2514856 | 0.00210807296175 | 0.5 | FNTA FNTB | The phototransduction cascade |
| GO:0004660 | 0.00270494046827 | 0.5 | FNTA FNTB | protein farnesyltransferase activity |
| GO:0005965 | 0.00270494046827 | 0.5 | FNTA FNTB | protein farnesyltransferase complex |
| GO:0018343 | 0.00811409485621 | 0.5 | FNTA FNTB | protein farnesylation |
| REAC:R-HSA-2187338 | 0.0277220764292 | 0.5 | FNTA FNTB | Visual phototransduction |
| GO:0008318 | 0.0405595771497 | 0.5 | FNTA FNTB | protein prenyltransferase activity |
| CORUM:6069 | 0.0499140284799 | 0.25 | GRIP1 | ESR1-GRIP1 complex |
| CORUM:6726 | 0.0499140284799 | 0.25 | GRIP1 | GRASP1-GRIP1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| FNTA | FNTB | 0.999 | 0.949 | bioplex (FNTB) bioplex_WMM |
| GRIP1 | FNTB | 0.097 | 0.359 | bioplex (FNTB) bioplex_WMM |
| UBL3 | FNTB | 0.033 | 0.248 | bioplex (FNTB) bioplex_WMM |
| GRIP1 | UBL3 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| FNTA | GRIP1 | 0.008 | 0.089 | bioplex_WMM WMM_only |
| FNTA | UBL3 | 0.008 | 0.066 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_00121 has an average edge precision of 0.301 which is ranked 4563 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| UBL3 | HuMAP2_00121 |
| FNTA | HuMAP2_00121 HuMAP2_00759 HuMAP2_01483 HuMAP2_01541 HuMAP2_02291 HuMAP2_03630 HuMAP2_05557 |
| GRIP1 | HuMAP2_00121 HuMAP2_00759 |
| FNTB | HuMAP2_00121 HuMAP2_00759 HuMAP2_02291 |