hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00127
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| WNK1 | Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Erythrocyte 65 kDa protein) (p65) (Kinase deficient protein) (Protein kinase lysine-deficient 1) (Protein kinase with no lysine 1) (hWNK1) | UniProt NCBI |
| DENND4A | C-myc promoter-binding protein (DENN domain-containing protein 4A) | UniProt NCBI |
| STIM1 | Stromal interaction molecule 1 | UniProt NCBI |
| METTL6 | Methyltransferase-like protein 6 (EC 2.1.1.-) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6108 | 0.0249595281251 | 0.25 | STIM1 | STIM1-TRPV4 complex |
| CORUM:1121 | 0.0499140284799 | 0.25 | WNK1 | WNK1-OSR1 complex |
| CORUM:1123 | 0.0499140284799 | 0.25 | WNK1 | WNK1-SPAK complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| METTL6 | STIM1 | 0.26 | 0.482 | bioplex (METTL6) bioplex_WMM |
| WNK1 | METTL6 | 0.042 | 0.27 | bioplex (METTL6) bioplex_WMM |
| DENND4A | METTL6 | 0.02 | 0.185 | bioplex (METTL6) bioplex_WMM |
| DENND4A | WNK1 | 0.008 | 0.032 | bioplex_WMM youn_WMM WMM_only |
| DENND4A | STIM1 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| WNK1 | STIM1 | 0.007 | 0.0 | bioplex_WMM youn_WMM WMM_only |
Images
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Complex HuMAP2_00127 has an average edge precision of 0.162 which is ranked 6606 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| WNK1 | HuMAP2_00127 HuMAP2_02179 HuMAP2_02967 HuMAP2_03839 |
| DENND4A | HuMAP2_00127 HuMAP2_01947 HuMAP2_03839 HuMAP2_06465 |
| STIM1 | HuMAP2_00127 HuMAP2_01616 HuMAP2_02179 HuMAP2_02898 HuMAP2_04889 |
| METTL6 | HuMAP2_00127 HuMAP2_01947 HuMAP2_02179 HuMAP2_02898 HuMAP2_03839 |