hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00132
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| EMC8 | ER membrane protein complex subunit 8 (Neighbor of COX4) (Protein FAM158B) | UniProt NCBI |
| EMC7 | ER membrane protein complex subunit 7 | UniProt NCBI |
| EMC10 | ER membrane protein complex subunit 10 (Hematopoietic signal peptide-containing membrane domain-containing protein 1) | UniProt NCBI |
| EMC4 | ER membrane protein complex subunit 4 (Cell proliferation-inducing gene 17 protein) (Transmembrane protein 85) | UniProt NCBI |
| EMC9 | ER membrane protein complex subunit 9 (Protein FAM158A) | UniProt NCBI |
| MMGT1 | Membrane magnesium transporter 1 (ER membrane protein complex subunit 5) (Transmembrane protein 32) | UniProt NCBI |
| EMC1 | ER membrane protein complex subunit 1 | UniProt NCBI |
| EMC2 | ER membrane protein complex subunit 2 (Tetratricopeptide repeat protein 35) (TPR repeat protein 35) | UniProt NCBI |
| EMC3 | ER membrane protein complex subunit 3 (Transmembrane protein 111) | UniProt NCBI |
| EMC6 | ER membrane protein complex subunit 6 (Transmembrane protein 93) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0072546 | 3.38791087736e-31 | 1.0 | EMC8 EMC6 MMGT1 EMC7 EMC2 EMC1 EMC9 EMC3 EMC10 EMC4 | ER membrane protein complex |
| GO:0030176 | 7.68534553236e-17 | 1.0 | EMC8 EMC6 MMGT1 EMC7 EMC2 EMC1 EMC9 EMC3 EMC10 EMC4 | integral component of endoplasmic reticulum membrane |
| GO:0031227 | 1.23537247832e-16 | 1.0 | EMC8 EMC6 MMGT1 EMC7 EMC2 EMC1 EMC9 EMC3 EMC10 EMC4 | intrinsic component of endoplasmic reticulum membrane |
| GO:0031301 | 1.02251520605e-13 | 1.0 | EMC8 EMC6 MMGT1 EMC7 EMC2 EMC1 EMC9 EMC3 EMC10 EMC4 | integral component of organelle membrane |
| GO:0031300 | 2.10665167153e-13 | 1.0 | EMC8 EMC6 MMGT1 EMC7 EMC2 EMC1 EMC9 EMC3 EMC10 EMC4 | intrinsic component of organelle membrane |
| GO:0005789 | 1.61484243403e-09 | 1.0 | EMC8 EMC6 MMGT1 EMC7 EMC2 EMC1 EMC9 EMC3 EMC10 EMC4 | endoplasmic reticulum membrane |
| GO:0042175 | 1.90205429534e-09 | 1.0 | EMC8 EMC6 MMGT1 EMC7 EMC2 EMC1 EMC9 EMC3 EMC10 EMC4 | nuclear outer membrane-endoplasmic reticulum membrane network |
| GO:0098796 | 2.10231420197e-08 | 1.0 | EMC8 EMC6 MMGT1 EMC7 EMC2 EMC1 EMC9 EMC3 EMC10 EMC4 | membrane protein complex |
| GO:0044432 | 3.77774807602e-08 | 1.0 | EMC8 EMC6 MMGT1 EMC7 EMC2 EMC1 EMC9 EMC3 EMC10 EMC4 | endoplasmic reticulum part |
| GO:0005783 | 1.37371218639e-06 | 1.0 | EMC8 EMC6 MMGT1 EMC7 EMC2 EMC1 EMC9 EMC3 EMC10 EMC4 | endoplasmic reticulum |
| GO:0016021 | 1.35052024294e-05 | 1.0 | EMC8 EMC6 MMGT1 EMC7 EMC2 EMC1 EMC9 EMC3 EMC10 EMC4 | integral component of membrane |
| GO:0031224 | 2.0489801185e-05 | 1.0 | EMC8 EMC6 MMGT1 EMC7 EMC2 EMC1 EMC9 EMC3 EMC10 EMC4 | intrinsic component of membrane |
| GO:0031090 | 0.000379261287957 | 1.0 | EMC8 EMC6 MMGT1 EMC7 EMC2 EMC1 EMC9 EMC3 EMC10 EMC4 | organelle membrane |
| GO:0044425 | 0.00622156805413 | 1.0 | EMC8 EMC6 MMGT1 EMC7 EMC2 EMC1 EMC9 EMC3 EMC10 EMC4 | membrane part |
| GO:0012505 | 0.00946154548006 | 1.0 | EMC8 EMC6 MMGT1 EMC7 EMC2 EMC1 EMC9 EMC3 EMC10 EMC4 | endomembrane system |
| MIRNA:hsa-miR-5089-5p | 0.0136517211587 | 0.4 | EMC7 EMC1 EMC3 EMC10 | hsa-miR-5089-5p |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| EMC3 | EMC2 | 1.0 | 0.949 | hein_WMM bioplex (EMC2,EMC3) bioplex_WMM youn_WMM hein (EMC2,EMC3) gupta_WMM |
| MMGT1 | EMC2 | 1.0 | 0.949 | hein_WMM bioplex (EMC2) bioplex_WMM youn_WMM hein (EMC2,MMGT1) gupta_WMM |
| EMC1 | EMC2 | 1.0 | 0.949 | hein_WMM bioplex (EMC2) bioplex_WMM youn_WMM hein (EMC1,EMC2) gupta_WMM |
| EMC4 | EMC2 | 1.0 | 0.949 | hein_WMM bioplex (EMC2) bioplex_WMM youn_WMM hein (EMC2) gupta_WMM |
| EMC8 | EMC2 | 1.0 | 0.949 | hein_WMM bioplex (EMC2) bioplex_WMM youn_WMM hein (EMC2) gupta_WMM |
| EMC7 | EMC2 | 1.0 | 0.949 | hein_WMM bioplex (EMC2,EMC7) bioplex_WMM youn_WMM hein (EMC2) gupta_WMM |
| EMC10 | EMC2 | 1.0 | 0.949 | hein_WMM bioplex (EMC2) bioplex_WMM youn_WMM hein (EMC2) gupta_WMM |
| EMC7 | EMC3 | 1.0 | 0.949 | hein_WMM bioplex (EMC3,EMC7) bioplex_WMM youn_WMM hein (EMC3) gupta_WMM |
| EMC7 | EMC1 | 1.0 | 0.949 | hein_WMM bioplex (EMC7) bioplex_WMM youn_WMM hein (EMC1) gupta_WMM fraction |
| EMC1 | EMC3 | 1.0 | 0.949 | hein_WMM bioplex (EMC3) bioplex_WMM youn_WMM hein (EMC1,EMC3) gupta_WMM |
| EMC4 | EMC3 | 1.0 | 0.949 | hein_WMM bioplex (EMC3) bioplex_WMM youn_WMM hein (EMC3) gupta_WMM |
| MMGT1 | EMC3 | 0.998 | 0.944 | hein_WMM bioplex (EMC3) bioplex_WMM youn_WMM hein (EMC3,MMGT1) gupta_WMM |
| EMC8 | EMC3 | 0.992 | 0.912 | hein_WMM bioplex_WMM youn_WMM hein (EMC3) gupta_WMM |
| EMC9 | EMC2 | 0.956 | 0.862 | bioplex (EMC2,EMC9) bioplex_WMM youn_WMM gupta_WMM |
| EMC7 | MMGT1 | 0.939 | 0.852 | hein_WMM bioplex (EMC7) bioplex_WMM youn_WMM hein (MMGT1) gupta_WMM |
| EMC2 | EMC6 | 0.922 | 0.843 | hein_WMM bioplex (EMC2) bioplex_WMM youn_WMM hein (EMC6) gupta_WMM |
| EMC8 | MMGT1 | 0.92 | 0.843 | hein_WMM bioplex_WMM youn_WMM hein (MMGT1) gupta_WMM |
| EMC8 | EMC1 | 0.91 | 0.834 | hein_WMM bioplex_WMM youn_WMM hein (EMC1) gupta_WMM |
| EMC7 | EMC8 | 0.825 | 0.774 | hein_WMM bioplex (EMC7) bioplex_WMM youn_WMM gupta_WMM |
| EMC4 | EMC6 | 0.813 | 0.773 | hein_WMM bioplex_WMM youn_WMM hein (EMC6) gupta_WMM |
| EMC4 | MMGT1 | 0.798 | 0.764 | hein_WMM bioplex_WMM youn_WMM hein (MMGT1) gupta_WMM |
| EMC4 | EMC1 | 0.792 | 0.758 | hein_WMM bioplex_WMM youn_WMM hein (EMC1) gupta_WMM |
| MMGT1 | EMC10 | 0.756 | 0.747 | hein_WMM bioplex_WMM youn_WMM hein (MMGT1) gupta_WMM |
| MMGT1 | EMC6 | 0.736 | 0.738 | hein_WMM bioplex_WMM youn_WMM hein (EMC6) gupta_WMM |
| EMC4 | EMC7 | 0.728 | 0.735 | hein_WMM bioplex (EMC7) bioplex_WMM youn_WMM gupta_WMM |
| EMC8 | EMC6 | 0.716 | 0.73 | hein_WMM bioplex_WMM youn_WMM hein (EMC6) gupta_WMM |
| EMC10 | EMC3 | 0.656 | 0.694 | hein_WMM bioplex (EMC3) bioplex_WMM youn_WMM gupta_WMM |
| MMGT1 | EMC1 | 0.638 | 0.686 | hein_WMM bioplex_WMM youn_WMM hein (EMC1,MMGT1) gupta_WMM |
| EMC10 | EMC1 | 0.511 | 0.63 | hein_WMM bioplex_WMM youn_WMM hein (EMC1) gupta_WMM |
| EMC7 | EMC10 | 0.482 | 0.613 | hein_WMM bioplex (EMC7) bioplex_WMM youn_WMM gupta_WMM |
| EMC10 | EMC6 | 0.432 | 0.578 | hein_WMM bioplex_WMM youn_WMM hein (EMC6) gupta_WMM |
| EMC9 | EMC3 | 0.424 | 0.575 | bioplex (EMC3,EMC9) bioplex_WMM youn_WMM gupta_WMM |
| EMC4 | EMC9 | 0.296 | 0.496 | bioplex (EMC9) bioplex_WMM youn_WMM gupta_WMM |
| EMC10 | EMC9 | 0.183 | 0.437 | bioplex (EMC9) bioplex_WMM youn_WMM gupta_WMM |
| EMC9 | EMC6 | 0.182 | 0.438 | bioplex (EMC9) bioplex_WMM youn_WMM gupta_WMM |
| EMC7 | EMC6 | 0.144 | 0.407 | hein_WMM bioplex_WMM youn_WMM hein (EMC6) gupta_WMM |
| EMC7 | EMC9 | 0.141 | 0.406 | bioplex (EMC7,EMC9) bioplex_WMM youn_WMM gupta_WMM |
| EMC1 | EMC9 | 0.113 | 0.38 | bioplex (EMC9) bioplex_WMM youn_WMM gupta_WMM |
| MMGT1 | EMC9 | 0.088 | 0.354 | bioplex (EMC9) bioplex_WMM youn_WMM gupta_WMM |
| EMC3 | EMC6 | 0.072 | 0.356 | hein_WMM bioplex_WMM youn_WMM hein (EMC6) gupta_WMM |
| EMC4 | EMC8 | 0.056 | 0.312 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| EMC4 | EMC10 | 0.032 | 0.242 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| EMC8 | EMC10 | 0.024 | 0.212 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| EMC8 | EMC9 | 0.009 | 0.112 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| EMC1 | EMC6 | 0.008 | 0.06 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_00132 has an average edge precision of 0.679 which is ranked 1472 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| EMC8 | HuMAP2_00132 HuMAP2_02699 |
| EMC7 | HuMAP2_00132 HuMAP2_02699 |
| EMC10 | HuMAP2_00132 HuMAP2_02699 |
| EMC4 | HuMAP2_00132 HuMAP2_02699 |
| EMC9 | HuMAP2_00132 |
| MMGT1 | HuMAP2_00132 HuMAP2_01365 HuMAP2_02699 |
| EMC1 | HuMAP2_00132 HuMAP2_02699 |
| EMC2 | HuMAP2_00132 HuMAP2_02699 HuMAP2_04941 |
| EMC3 | HuMAP2_00132 HuMAP2_02699 |
| EMC6 | HuMAP2_00132 HuMAP2_02699 |