hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00136
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MFSD4B | Sodium-dependent glucose transporter 1 (Major facilitator superfamily domain-containing protein 4B) | UniProt NCBI |
| TUBA3D | Tubulin alpha-3D chain (Alpha-tubulin 3D) [Cleaved into: Detyrosinated tubulin alpha-3D chain] | UniProt NCBI |
| LGALS7 | Galectin-7 (Gal-7) (HKL-14) (PI7) (p53-induced gene 1 protein) | UniProt NCBI |
| TUBA1B | Tubulin alpha-1B chain (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain] | UniProt NCBI |
| TCP11L2 | T-complex protein 11-like protein 2 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-190840 | 0.00136571756437 | 0.5 | TUBA1B TUBA3D | Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane |
| REAC:R-HSA-190872 | 0.00153629461685 | 0.5 | TUBA1B TUBA3D | Transport of connexons to the plasma membrane |
| REAC:R-HSA-389977 | 0.00210807296175 | 0.5 | TUBA1B TUBA3D | Post-chaperonin tubulin folding pathway |
| WP:WP2272 | 0.00221783487587 | 0.5 | TUBA1B TUBA3D | Pathogenic Escherichia coli infection |
| REAC:R-HSA-190861 | 0.00253927088831 | 0.5 | TUBA1B TUBA3D | Gap junction assembly |
| REAC:R-HSA-9619483 | 0.00276986547413 | 0.5 | TUBA1B TUBA3D | Activation of AMPK downstream of NMDARs |
| REAC:R-HSA-389960 | 0.00276986547413 | 0.5 | TUBA1B TUBA3D | Formation of tubulin folding intermediates by CCT/TriC |
| WP:WP2359 | 0.00358316968152 | 0.5 | TUBA1B TUBA3D | Parkin-Ubiquitin Proteasomal System pathway |
| REAC:R-HSA-5626467 | 0.00379215175563 | 0.5 | TUBA1B TUBA3D | RHO GTPases activate IQGAPs |
| REAC:R-HSA-389958 | 0.00466369436644 | 0.5 | TUBA1B TUBA3D | Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding |
| REAC:R-HSA-190828 | 0.00562500866147 | 0.5 | TUBA1B TUBA3D | Gap junction trafficking |
| REAC:R-HSA-157858 | 0.00596538345738 | 0.5 | TUBA1B TUBA3D | Gap junction trafficking and regulation |
| REAC:R-HSA-8955332 | 0.00667602194349 | 0.5 | TUBA1B TUBA3D | Carboxyterminal post-translational modifications of tubulin |
| KEGG:04540 | 0.00693358165081 | 0.5 | TUBA1B TUBA3D | Gap junction |
| REAC:R-HSA-9609736 | 0.0070462802506 | 0.5 | TUBA1B TUBA3D | Assembly and cell surface presentation of NMDA receptors |
| REAC:R-HSA-437239 | 0.00991669978918 | 0.5 | TUBA1B TUBA3D | Recycling pathway of L1 |
| REAC:R-HSA-6811436 | 0.0122651619918 | 0.5 | TUBA1B TUBA3D | COPI-independent Golgi-to-ER retrograde traffic |
| REAC:R-HSA-5620924 | 0.012764635731 | 0.5 | TUBA1B TUBA3D | Intraflagellar transport |
| REAC:R-HSA-3371497 | 0.013274030298 | 0.5 | TUBA1B TUBA3D | HSP90 chaperone cycle for steroid hormone receptors (SHR) |
| KEGG:04210 | 0.0153578793248 | 0.5 | TUBA1B TUBA3D | Apoptosis |
| REAC:R-HSA-983189 | 0.0159697215039 | 0.5 | TUBA1B TUBA3D | Kinesins |
| KEGG:04145 | 0.0179080093657 | 0.5 | TUBA1B TUBA3D | Phagosome |
| KEGG:04530 | 0.0206513420529 | 0.5 | TUBA1B TUBA3D | Tight junction |
| REAC:R-HSA-1445148 | 0.0227713839361 | 0.5 | TUBA1B TUBA3D | Translocation of SLC2A4 (GLUT4) to the plasma membrane |
| REAC:R-HSA-438064 | 0.0262582706021 | 0.5 | TUBA1B TUBA3D | Post NMDA receptor activation events |
| REAC:R-HSA-8852276 | 0.0284687652941 | 0.5 | TUBA1B TUBA3D | The role of GTSE1 in G2/M progression after G2 checkpoint |
| KEGG:05130 | 0.0307221505972 | 0.5 | TUBA1B TUBA3D | Pathogenic Escherichia coli infection |
| REAC:R-HSA-442755 | 0.0347967852364 | 0.5 | TUBA1B TUBA3D | Activation of NMDA receptors and postsynaptic events |
| REAC:R-HSA-380320 | 0.0399558314157 | 0.5 | TUBA1B TUBA3D | Recruitment of NuMA to mitotic centrosomes |
| REAC:R-HSA-390466 | 0.0399558314157 | 0.5 | TUBA1B TUBA3D | Chaperonin-mediated protein folding |
| REAC:R-HSA-391251 | 0.0454682616856 | 0.5 | TUBA1B TUBA3D | Protein folding |
| REAC:R-HSA-6811434 | 0.0454682616856 | 0.5 | TUBA1B TUBA3D | COPI-dependent Golgi-to-ER retrograde traffic |
| REAC:R-HSA-6807878 | 0.0464213162589 | 0.5 | TUBA1B TUBA3D | COPI-mediated anterograde transport |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TUBA3D | TCP11L2 | 0.163 | 0.42 | bioplex (TUBA3D) bioplex_WMM |
| MFSD4B | TUBA3D | 0.154 | 0.414 | bioplex (TUBA3D) bioplex_WMM |
| TUBA1B | TCP11L2 | 0.136 | 0.406 | hein_WMM bioplex (TUBA1B) bioplex_WMM |
| TUBA3D | LGALS7 | 0.076 | 0.355 | bioplex (LGALS7) |
| MFSD4B | TCP11L2 | 0.007 | 0.01 | bioplex_WMM WMM_only |
| TUBA1B | MFSD4B | 0.007 | 0.006 | bioplex_WMM boldt boldt_WMM |
| TUBA1B | TUBA3D | 0.006 | 0.006 | bioplex_WMM boldt |
| TUBA1B | LGALS7 | 0.006 | 0.005 | bioplex (LGALS7) boldt boldt_WMM |
Images
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Complex HuMAP2_00136 has an average edge precision of 0.203 which is ranked 6141 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MFSD4B | HuMAP2_00136 HuMAP2_02206 HuMAP2_04472 HuMAP2_04770 |
| TUBA3D | HuMAP2_00136 HuMAP2_02206 HuMAP2_04472 HuMAP2_04770 HuMAP2_06635 |
| LGALS7 | HuMAP2_00136 HuMAP2_00544 |
| TUBA1B | HuMAP2_00105 HuMAP2_00136 HuMAP2_02619 HuMAP2_03406 HuMAP2_04472 |
| TCP11L2 | HuMAP2_00136 HuMAP2_02206 HuMAP2_02619 HuMAP2_03406 HuMAP2_04472 HuMAP2_04770 |