hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00160
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NIF3L1 | NIF3-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein) | UniProt NCBI |
| AVP | Vasopressin-neurophysin 2-copeptin (AVP-NPII) [Cleaved into: Arg-vasopressin (Arginine-vasopressin); Neurophysin 2 (Neurophysin-II); Copeptin] | UniProt NCBI |
| KRTAP13-2 | Keratin-associated protein 13-2 | UniProt NCBI |
| NUDT8 | Nucleoside diphosphate-linked moiety X motif 8 (Nudix motif 8) (EC 3.6.1.-) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:023030_03 | 0.0419632066604 | 0.25 | AVP | hypothalamus; neuronal projections[Uncertain,High] |
| HPA:023030_13 | 0.0419632066604 | 0.25 | AVP | hypothalamus; neuronal projections[Supported,High] |
| REAC:R-HSA-9036092 | 0.0499190562503 | 0.25 | AVP | Defective AVP does not bind AVPR2 and causes neurohypophyseal diabetes insipidus (NDI) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NIF3L1 | KRTAP13-2 | 0.489 | 0.617 | bioplex () |
| NUDT8 | KRTAP13-2 | 0.065 | 0.347 | bioplex () |
| NIF3L1 | AVP | 0.037 | 0.265 | bioplex (AVP) bioplex_WMM |
| NUDT8 | NIF3L1 | 0.007 | 0.003 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_00160 has an average edge precision of 0.308 which is ranked 4476 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NIF3L1 | HuMAP2_00160 HuMAP2_00527 HuMAP2_04343 HuMAP2_05580 |
| AVP | HuMAP2_00160 HuMAP2_00527 HuMAP2_01263 HuMAP2_04343 |
| KRTAP13-2 | HuMAP2_00160 HuMAP2_00527 HuMAP2_04343 HuMAP2_05037 HuMAP2_05580 |
| NUDT8 | HuMAP2_00030 HuMAP2_00160 HuMAP2_01412 HuMAP2_01497 HuMAP2_05037 |