hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00162
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MBOAT7 | Lysophospholipid acyltransferase 7 (LPLAT 7) (EC 2.3.1.-) (1-acylglycerophosphatidylinositol O-acyltransferase) (EC 2.3.1.n4) (Bladder and breast carcinoma-overexpressed gene 1 protein) (Leukocyte receptor cluster member 4) (Lysophosphatidylinositol acyltransferase) (LPIAT) (Lyso-PI acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 7) (O-acyltransferase domain-containing protein 7) (h-mboa-7) | UniProt NCBI |
| TICAM2 | TIR domain-containing adapter molecule 2 (TICAM-2) (Putative NF-kappa-B-activating protein 502) (TRIF-related adapter molecule) (Toll-like receptor adaptor protein 3) (Toll/interleukin-1 receptor domain-containing protein) (MyD88-4) | UniProt NCBI |
| TMED1 | Transmembrane emp24 domain-containing protein 1 (Interleukin-1 receptor-like 1 ligand) (Putative T1/ST2 receptor-binding protein) (p24 family protein gamma-1) (Tp24) (p24gamma1) | UniProt NCBI |
| STOM | Erythrocyte band 7 integral membrane protein (Protein 7.2b) (Stomatin) | UniProt NCBI |
| TMED5 | Transmembrane emp24 domain-containing protein 5 (p24 family protein gamma-2) (p24gamma2) (p28) | UniProt NCBI |
| TMED3 | Transmembrane emp24 domain-containing protein 3 (Membrane protein p24B) (p24 family protein gamma-4) (p24gamma4) (p26) | UniProt NCBI |
| TMED10 | Transmembrane emp24 domain-containing protein 10 (21 kDa transmembrane-trafficking protein) (S31III125) (S31I125) (Tmp-21-I) (Transmembrane protein Tmp21) (p23) (p24 family protein delta-1) (p24delta1) (p24delta) | UniProt NCBI |
| TMED4 | Transmembrane emp24 domain-containing protein 4 (Endoplasmic reticulum stress-response protein 25) (ERS25) (GMP25iso) (Putative NF-kappa-B-activating protein 156) (p24 family protein alpha-3) (p24alpha3) | UniProt NCBI |
| TMED7 | Transmembrane emp24 domain-containing protein 7 (p24 family protein gamma-3) (p24gamma3) (p27) | UniProt NCBI |
| LIPG | Endothelial lipase (EC 3.1.1.3) (Endothelial cell-derived lipase) (EDL) (EL) | UniProt NCBI |
| TMED2 | Transmembrane emp24 domain-containing protein 2 (Membrane protein p24A) (p24) (p24 family protein beta-1) (p24beta1) | UniProt NCBI |
| TMED9 | Transmembrane emp24 domain-containing protein 9 (GMP25) (Glycoprotein 25L2) (p24 family protein alpha-2) (p24alpha2) (p25) | UniProt NCBI |
| GOLGB1 | Golgin subfamily B member 1 (372 kDa Golgi complex-associated protein) (GCP372) (Giantin) (Macrogolgin) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0005793 | 2.63916307145e-16 | 0.769230769231 | TMED5 TMED7 TMED1 TMED10 GOLGB1 TICAM2 TMED9 TMED2 TMED4 TMED3 | endoplasmic reticulum-Golgi intermediate compartment |
| GO:0007030 | 9.25719052656e-15 | 0.769230769231 | TMED5 TMED7 TMED1 TMED10 GOLGB1 TICAM2 TMED9 TMED2 TMED4 TMED3 | Golgi organization |
| GO:0030134 | 3.44659383676e-14 | 0.692307692308 | TMED5 TMED7 TMED1 TMED10 TICAM2 TMED9 TMED2 TMED4 TMED3 | COPII-coated ER to Golgi transport vesicle |
| GO:0006888 | 8.48232543694e-13 | 0.769230769231 | TMED5 TMED7 TMED1 TMED10 GOLGB1 TICAM2 TMED9 TMED2 TMED4 TMED3 | endoplasmic reticulum to Golgi vesicle-mediated transport |
| GO:0005798 | 1.17017415422e-11 | 0.692307692308 | TMED5 TMED7 TMED1 TMED10 TICAM2 TMED9 TMED2 TMED4 TMED3 | Golgi-associated vesicle |
| GO:0048193 | 3.4626072073e-10 | 0.769230769231 | TMED5 TMED7 TMED1 TMED10 GOLGB1 TICAM2 TMED9 TMED2 TMED4 TMED3 | Golgi vesicle transport |
| GO:0010256 | 3.679297015e-10 | 0.769230769231 | TMED5 TMED7 TMED1 TMED10 GOLGB1 TICAM2 TMED9 TMED2 TMED4 TMED3 | endomembrane system organization |
| GO:0030135 | 6.04735227912e-10 | 0.692307692308 | TMED5 TMED7 TMED1 TMED10 TICAM2 TMED9 TMED2 TMED4 TMED3 | coated vesicle |
| REAC:R-HSA-6807878 | 2.58171854963e-08 | 0.461538461538 | TMED10 GOLGB1 TMED3 TMED9 TMED2 TMED7 | COPI-mediated anterograde transport |
| REAC:R-HSA-199977 | 2.8563882604e-07 | 0.461538461538 | TMED10 GOLGB1 TMED3 TMED9 TMED2 TMED7 | ER to Golgi Anterograde Transport |
| REAC:R-HSA-948021 | 7.5059729895e-07 | 0.461538461538 | TMED10 GOLGB1 TMED3 TMED9 TMED2 TMED7 | Transport to the Golgi and subsequent modification |
| GO:0005794 | 7.71432660585e-07 | 0.846153846154 | TMED5 TMED7 LIPG TMED1 TMED10 GOLGB1 TICAM2 TMED9 TMED2 TMED4 TMED3 | Golgi apparatus |
| REAC:R-HSA-6811434 | 2.96002369638e-06 | 0.384615384615 | TMED10 TMED3 TMED2 TMED9 TMED7 | COPI-dependent Golgi-to-ER retrograde traffic |
| GO:0033116 | 4.5302289781e-06 | 0.384615384615 | TMED10 TMED3 TMED2 TMED9 TMED7 | endoplasmic reticulum-Golgi intermediate compartment membrane |
| GO:0005783 | 7.93651918945e-06 | 0.846153846154 | STOM TMED5 TMED7 TMED3 TMED1 TMED10 MBOAT7 TMED9 TMED2 TMED4 TICAM2 | endoplasmic reticulum |
| REAC:R-HSA-8856688 | 1.36513009261e-05 | 0.384615384615 | TMED10 TMED3 TMED2 TMED9 TMED7 | Golgi-to-ER retrograde transport |
| REAC:R-HSA-446203 | 1.70839115405e-05 | 0.461538461538 | TMED10 GOLGB1 TMED3 TMED9 TMED2 TMED7 | Asparagine N-linked glycosylation |
| GO:0016192 | 4.70076894069e-05 | 0.846153846154 | STOM TMED5 TMED7 TMED1 TMED10 GOLGB1 TICAM2 TMED9 TMED2 TMED4 TMED3 | vesicle-mediated transport |
| GO:0031410 | 4.97069497683e-05 | 0.846153846154 | STOM TMED5 TMED7 LIPG TMED1 TMED10 TICAM2 TMED9 TMED2 TMED4 TMED3 | cytoplasmic vesicle |
| GO:0097708 | 5.00540412114e-05 | 0.846153846154 | STOM TMED5 TMED7 LIPG TMED1 TMED10 TICAM2 TMED9 TMED2 TMED4 TMED3 | intracellular vesicle |
| GO:0012505 | 9.05632172409e-05 | 1.0 | STOM TMED5 TMED7 TMED3 TMED1 LIPG TMED10 GOLGB1 MBOAT7 TMED9 TMED2 TMED4 TICAM2 | endomembrane system |
| REAC:R-HSA-6811442 | 0.000108704758107 | 0.384615384615 | TMED10 TMED3 TMED2 TMED9 TMED7 | Intra-Golgi and retrograde Golgi-to-ER traffic |
| GO:0030137 | 0.000126487933889 | 0.307692307692 | TMED10 TMED2 TMED3 TMED7 | COPI-coated vesicle |
| MIRNA:hsa-miR-30a-5p | 0.000246461966358 | 0.538461538462 | TMED5 TMED7 TMED1 TMED10 TICAM2 TMED2 TMED3 | hsa-miR-30a-5p |
| GO:0006890 | 0.000333634431211 | 0.384615384615 | TMED10 TMED3 TMED2 TMED9 TMED7 | retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum |
| GO:0006886 | 0.000356258930511 | 0.692307692308 | TMED5 TMED7 TMED1 TMED10 TICAM2 TMED9 TMED2 TMED4 TMED3 | intracellular protein transport |
| GO:0035964 | 0.000518697707158 | 0.230769230769 | TMED10 TMED9 TMED2 | COPI-coated vesicle budding |
| GO:0048205 | 0.000518697707158 | 0.230769230769 | TMED10 TMED9 TMED2 | COPI coating of Golgi vesicle |
| GO:0048200 | 0.000518697707158 | 0.230769230769 | TMED10 TMED9 TMED2 | Golgi transport vesicle coating |
| GO:0046907 | 0.000685850006555 | 0.769230769231 | TMED5 TMED7 TMED1 TMED10 GOLGB1 TICAM2 TMED9 TMED2 TMED4 TMED3 | intracellular transport |
| REAC:R-HSA-199991 | 0.00111527877237 | 0.461538461538 | TMED10 GOLGB1 TMED3 TMED9 TMED2 TMED7 | Membrane Trafficking |
| GO:0034613 | 0.00120514713924 | 0.769230769231 | TMED5 TMED7 TMED1 TMED10 GOLGB1 TICAM2 TMED9 TMED2 TMED4 TMED3 | cellular protein localization |
| GO:0070727 | 0.00127679422454 | 0.769230769231 | TMED5 TMED7 TMED1 TMED10 GOLGB1 TICAM2 TMED9 TMED2 TMED4 TMED3 | cellular macromolecule localization |
| REAC:R-HSA-5653656 | 0.00152021907415 | 0.461538461538 | TMED10 GOLGB1 TMED3 TMED9 TMED2 TMED7 | Vesicle-mediated transport |
| GO:0033036 | 0.00191148637257 | 0.846153846154 | TMED5 TMED7 LIPG TMED1 TMED10 GOLGB1 TICAM2 TMED9 TMED2 TMED4 TMED3 | macromolecule localization |
| GO:0051649 | 0.00508948108027 | 0.769230769231 | TMED5 TMED7 TMED1 TMED10 GOLGB1 TICAM2 TMED9 TMED2 TMED4 TMED3 | establishment of localization in cell |
| GO:0071702 | 0.00629517217375 | 0.769230769231 | TMED5 TMED7 LIPG TMED1 TMED10 TICAM2 TMED9 TMED2 TMED4 TMED3 | organic substance transport |
| GO:0015031 | 0.00862570985723 | 0.692307692308 | TMED5 TMED7 TMED1 TMED10 TICAM2 TMED9 TMED2 TMED4 TMED3 | protein transport |
| GO:0015833 | 0.00976188584178 | 0.692307692308 | TMED5 TMED7 TMED1 TMED10 TICAM2 TMED9 TMED2 TMED4 TMED3 | peptide transport |
| GO:0042886 | 0.0108879182674 | 0.692307692308 | TMED5 TMED7 TMED1 TMED10 TICAM2 TMED9 TMED2 TMED4 TMED3 | amide transport |
| GO:0044431 | 0.0115479002987 | 0.538461538462 | TMED5 TMED10 GOLGB1 TMED3 TMED9 TMED2 TMED7 | Golgi apparatus part |
| GO:0051179 | 0.0149186696665 | 1.0 | STOM TMED5 TMED7 TMED3 TMED1 LIPG TMED10 GOLGB1 MBOAT7 TMED9 TMED2 TMED4 TICAM2 | localization |
| GO:0008104 | 0.0151516620016 | 0.769230769231 | TMED5 TMED7 TMED1 TMED10 GOLGB1 TICAM2 TMED9 TMED2 TMED4 TMED3 | protein localization |
| GO:0045184 | 0.0167184339691 | 0.692307692308 | TMED5 TMED7 TMED1 TMED10 TICAM2 TMED9 TMED2 TMED4 TMED3 | establishment of protein localization |
| GO:0006810 | 0.0196880371483 | 0.923076923077 | STOM TMED5 TMED7 LIPG TMED1 TMED10 GOLGB1 TICAM2 TMED9 TMED2 TMED4 TMED3 | transport |
| GO:0051234 | 0.0277609848935 | 0.923076923077 | STOM TMED5 TMED7 LIPG TMED1 TMED10 GOLGB1 TICAM2 TMED9 TMED2 TMED4 TMED3 | establishment of localization |
| GO:0000139 | 0.030124941082 | 0.461538461538 | TMED10 GOLGB1 TMED3 TMED9 TMED2 TMED7 | Golgi membrane |
| GO:0071705 | 0.0326237225218 | 0.692307692308 | TMED5 TMED7 TMED1 TMED10 TICAM2 TMED9 TMED2 TMED4 TMED3 | nitrogen compound transport |
| GO:0030660 | 0.0355984541506 | 0.307692307692 | TMED10 TMED2 TMED3 TMED7 | Golgi-associated vesicle membrane |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TMED10 | TMED2 | 1.0 | 0.949 | hein_WMM bioplex (TMED10) bioplex_WMM Guru boldt hein (TMED10,TMED2) gupta_WMM fraction boldt_WMM treiber_WMM |
| TMED4 | TMED2 | 1.0 | 0.949 | hein_WMM bioplex (TMED2) bioplex_WMM Guru boldt hein (TMED2) fraction boldt_WMM treiber_WMM |
| TMED10 | TMED9 | 1.0 | 0.949 | hein_WMM bioplex (TMED10) bioplex_WMM Guru boldt hein (TMED10) gupta_WMM fraction boldt_WMM treiber_WMM |
| TMED10 | TMED4 | 1.0 | 0.949 | hein_WMM bioplex (TMED10) bioplex_WMM Guru boldt hein (TMED10) fraction boldt_WMM treiber_WMM |
| TMED1 | TMED2 | 0.999 | 0.949 | hein_WMM bioplex (TMED2) bioplex_WMM boldt hein (TMED2) boldt_WMM |
| TMED10 | TMED1 | 0.999 | 0.945 | hein_WMM bioplex (TMED10) bioplex_WMM boldt hein (TMED10) boldt_WMM |
| TMED2 | TMED9 | 0.997 | 0.934 | hein_WMM bioplex_WMM Guru boldt hein (TMED2) gupta_WMM fraction boldt_WMM treiber_WMM |
| TMED2 | TMED3 | 0.994 | 0.923 | hein_WMM bioplex (TMED2,TMED3) bioplex_WMM hein (TMED2) fraction |
| TMED2 | TMED5 | 0.992 | 0.911 | hein_WMM bioplex (TMED2) bioplex_WMM boldt hein (TMED2) gupta_WMM boldt_WMM |
| TMED10 | TMED5 | 0.984 | 0.899 | hein_WMM bioplex (TMED10) bioplex_WMM boldt hein (TMED10) gupta_WMM boldt_WMM |
| TMED10 | TMED3 | 0.885 | 0.817 | hein_WMM bioplex (TMED10,TMED3) bioplex_WMM hein (TMED10) fraction |
| TMED2 | GOLGB1 | 0.374 | 0.546 | hein_WMM bioplex (TMED2) bioplex_WMM hein (TMED2) gupta_WMM |
| TICAM2 | TMED2 | 0.214 | 0.464 | hein_WMM hein (TMED2) |
| TMED7 | TMED2 | 0.145 | 0.408 | bioplex (TMED2) bioplex_WMM |
| LIPG | TMED5 | 0.098 | 0.358 | bioplex (LIPG) bioplex_WMM |
| TMED10 | TMED7 | 0.056 | 0.312 | bioplex (TMED10) bioplex_WMM |
| LIPG | TMED9 | 0.051 | 0.296 | bioplex (LIPG) bioplex_WMM |
| MBOAT7 | TMED2 | 0.045 | 0.292 | hein_WMM bioplex_WMM boldt hein (TMED2) gupta_WMM boldt_WMM |
| STOM | TMED2 | 0.031 | 0.241 | hein_WMM bioplex_WMM boldt hein (TMED2) gupta_WMM boldt_WMM treiber_WMM |
| LIPG | TMED2 | 0.031 | 0.242 | bioplex (LIPG) bioplex_WMM |
| TMED4 | LIPG | 0.029 | 0.232 | bioplex (LIPG) bioplex_WMM |
| TMED4 | TMED9 | 0.024 | 0.214 | hein_WMM bioplex_WMM boldt boldt_WMM treiber_WMM |
| TMED1 | TMED4 | 0.023 | 0.205 | hein_WMM bioplex_WMM boldt boldt_WMM |
| TMED1 | TMED5 | 0.021 | 0.193 | hein_WMM bioplex_WMM boldt boldt_WMM |
| TMED5 | TMED9 | 0.018 | 0.178 | hein_WMM bioplex_WMM boldt gupta_WMM boldt_WMM |
| TMED1 | TMED9 | 0.016 | 0.158 | hein_WMM bioplex_WMM boldt boldt_WMM |
| TMED10 | TICAM2 | 0.016 | 0.155 | hein_WMM hein (TMED10) |
| TMED4 | TMED5 | 0.016 | 0.154 | hein_WMM bioplex_WMM boldt boldt_WMM |
| TMED10 | LIPG | 0.015 | 0.139 | bioplex (LIPG) bioplex_WMM |
| STOM | MBOAT7 | 0.014 | 0.138 | hein_WMM bioplex_WMM boldt (STOM) youn_WMM boldt_WMM |
| TMED9 | TMED3 | 0.011 | 0.142 | hein_WMM bioplex_WMM WMM_only |
| TMED5 | TMED3 | 0.01 | 0.137 | hein_WMM bioplex_WMM WMM_only |
| TMED7 | TMED3 | 0.01 | 0.134 | bioplex_WMM WMM_only |
| TMED1 | TMED3 | 0.01 | 0.131 | hein_WMM bioplex_WMM WMM_only |
| TICAM2 | TMED9 | 0.01 | 0.101 | hein_WMM WMM_only |
| TICAM2 | TMED3 | 0.009 | 0.099 | hein_WMM WMM_only |
| TICAM2 | TMED5 | 0.009 | 0.099 | hein_WMM WMM_only |
| TMED1 | TICAM2 | 0.009 | 0.099 | hein_WMM WMM_only |
| TMED4 | GOLGB1 | 0.008 | 0.084 | hein_WMM bioplex_WMM WMM_only |
| GOLGB1 | TMED3 | 0.008 | 0.082 | hein_WMM bioplex_WMM WMM_only |
| TMED4 | TICAM2 | 0.008 | 0.082 | hein_WMM WMM_only |
| TMED5 | GOLGB1 | 0.008 | 0.061 | hein_WMM bioplex_WMM WMM_only |
| TMED7 | GOLGB1 | 0.008 | 0.015 | bioplex_WMM WMM_only |
| TMED1 | GOLGB1 | 0.007 | 0.01 | hein_WMM bioplex_WMM WMM_only |
| TMED9 | GOLGB1 | 0.007 | 0.006 | hein_WMM bioplex_WMM WMM_only boldt_WMM |
| TMED4 | TMED7 | 0.007 | 0.009 | bioplex_WMM WMM_only |
| TMED7 | TMED9 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| TICAM2 | GOLGB1 | 0.007 | 0.001 | hein_WMM WMM_only |
| TMED7 | TMED5 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| MBOAT7 | TICAM2 | 0.007 | 0.006 | hein_WMM WMM_only |
| MBOAT7 | TMED5 | 0.007 | 0.002 | hein_WMM bioplex_WMM WMM_only |
| MBOAT7 | GOLGB1 | 0.007 | 0.005 | hein_WMM bioplex_WMM WMM_only |
| TMED4 | MBOAT7 | 0.007 | 0.004 | hein_WMM bioplex_WMM WMM_only |
| STOM | TICAM2 | 0.007 | 0.004 | hein_WMM WMM_only |
| MBOAT7 | TMED3 | 0.006 | 0.0 | hein_WMM bioplex_WMM WMM_only |
| STOM | GOLGB1 | 0.006 | 0.004 | hein_WMM bioplex_WMM gupta_WMM WMM_only |
| MBOAT7 | TMED9 | 0.006 | 0.003 | hein_WMM bioplex_WMM gupta_WMM WMM_only |
| STOM | TMED3 | 0.006 | 0.004 | hein_WMM bioplex_WMM WMM_only |
| TMED10 | MBOAT7 | 0.006 | 0.005 | hein_WMM bioplex_WMM boldt gupta_WMM boldt_WMM |
| MBOAT7 | TMED7 | 0.006 | 0.008 | bioplex_WMM WMM_only |
| TMED1 | LIPG | 0.006 | 0.007 | bioplex (LIPG) bioplex_WMM |
| TMED1 | TMED7 | 0.006 | 0.007 | bioplex_WMM WMM_only |
| STOM | TMED4 | 0.006 | 0.003 | hein_WMM bioplex_WMM WMM_only treiber_WMM |
| TMED10 | GOLGB1 | 0.006 | 0.009 | hein_WMM bioplex (TMED10) bioplex_WMM gupta_WMM boldt_WMM |
| TMED10 | STOM | 0.006 | 0.007 | hein_WMM bioplex_WMM boldt (STOM) gupta_WMM boldt_WMM treiber_WMM |
| STOM | TMED5 | 0.006 | 0.008 | hein_WMM bioplex_WMM WMM_only |
| TMED1 | MBOAT7 | 0.006 | 0.006 | hein_WMM bioplex_WMM boldt boldt_WMM |
| STOM | TMED9 | 0.005 | 0.013 | hein_WMM bioplex_WMM WMM_only treiber_WMM |
| TMED1 | STOM | 0.005 | 0.01 | hein_WMM bioplex_WMM WMM_only |
| TMED4 | TMED3 | 0.003 | 0.018 | hein_WMM bioplex (TMED3) bioplex_WMM |
Images
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Complex HuMAP2_00162 has an average edge precision of 0.236 which is ranked 5596 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MBOAT7 | HuMAP2_00162 |
| TICAM2 | HuMAP2_00162 |
| TMED1 | HuMAP2_00162 HuMAP2_02885 HuMAP2_06043 |
| STOM | HuMAP2_00162 HuMAP2_01801 HuMAP2_02408 |
| TMED5 | HuMAP2_00162 HuMAP2_02885 HuMAP2_06043 |
| TMED3 | HuMAP2_00162 HuMAP2_02885 HuMAP2_05043 |
| TMED10 | HuMAP2_00162 HuMAP2_02885 HuMAP2_06043 |
| TMED4 | HuMAP2_00162 HuMAP2_02885 HuMAP2_06043 |
| TMED7 | HuMAP2_00162 HuMAP2_06043 |
| LIPG | HuMAP2_00162 HuMAP2_06043 HuMAP2_06507 |
| TMED2 | HuMAP2_00162 HuMAP2_02885 |
| TMED9 | HuMAP2_00162 HuMAP2_02885 HuMAP2_06043 |
| GOLGB1 | HuMAP2_00162 HuMAP2_04346 |