hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00164
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PGAM1 | Phosphoglycerate mutase 1 (EC 5.4.2.11) (EC 5.4.2.4) (BPG-dependent PGAM 1) (Phosphoglycerate mutase isozyme B) (PGAM-B) | UniProt NCBI |
| PGAM4 | Probable phosphoglycerate mutase 4 (EC 5.4.2.11) (EC 5.4.2.4) | UniProt NCBI |
| PGAM2 | Phosphoglycerate mutase 2 (EC 5.4.2.11) (EC 5.4.2.4) (BPG-dependent PGAM 2) (Muscle-specific phosphoglycerate mutase) (Phosphoglycerate mutase isozyme M) (PGAM-M) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0004619 | 9.08185760231e-08 | 1.0 | PGAM2 PGAM1 PGAM4 | phosphoglycerate mutase activity |
| KEGG:00260 | 2.74831445787e-07 | 1.0 | PGAM2 PGAM1 PGAM4 | Glycine, serine and threonine metabolism |
| KEGG:00010 | 1.19420412995e-06 | 1.0 | PGAM2 PGAM1 PGAM4 | Glycolysis / Gluconeogenesis |
| KEGG:05230 | 1.44061718026e-06 | 1.0 | PGAM2 PGAM1 PGAM4 | Central carbon metabolism in cancer |
| KEGG:01230 | 1.7187866598e-06 | 1.0 | PGAM2 PGAM1 PGAM4 | Biosynthesis of amino acids |
| KEGG:04922 | 4.29674110668e-06 | 1.0 | PGAM2 PGAM1 PGAM4 | Glucagon signaling pathway |
| KEGG:01200 | 7.23132386252e-06 | 1.0 | PGAM2 PGAM1 PGAM4 | Carbon metabolism |
| GO:0016868 | 1.08982291228e-05 | 1.0 | PGAM2 PGAM1 PGAM4 | intramolecular transferase activity, phosphotransferases |
| GO:0016866 | 0.000160839698137 | 1.0 | PGAM2 PGAM1 PGAM4 | intramolecular transferase activity |
| WP:WP534 | 0.000905695914221 | 0.666666666667 | PGAM1 PGAM2 | Glycolysis and Gluconeogenesis |
| REAC:R-HSA-70263 | 0.00290884705451 | 0.666666666667 | PGAM1 PGAM2 | Gluconeogenesis |
| MIRNA:hsa-miR-3907 | 0.00671144668107 | 0.666666666667 | PGAM1 PGAM4 | hsa-miR-3907 |
| MIRNA:hsa-miR-6772-3p | 0.00997289627319 | 0.666666666667 | PGAM1 PGAM4 | hsa-miR-6772-3p |
| KEGG:01100 | 0.0105851300972 | 1.0 | PGAM2 PGAM1 PGAM4 | Metabolic pathways |
| MIRNA:hsa-miR-7112-5p | 0.0108886199752 | 0.666666666667 | PGAM1 PGAM4 | hsa-miR-7112-5p |
| GO:0006096 | 0.0117851633362 | 1.0 | PGAM2 PGAM1 PGAM4 | glycolytic process |
| MIRNA:hsa-miR-4697-3p | 0.0118444665109 | 0.666666666667 | PGAM1 PGAM4 | hsa-miR-4697-3p |
| GO:0006757 | 0.0121736852044 | 1.0 | PGAM2 PGAM1 PGAM4 | ATP generation from ADP |
| GO:0046031 | 0.0129761581422 | 1.0 | PGAM2 PGAM1 PGAM4 | ADP metabolic process |
| GO:0009179 | 0.0138131421388 | 1.0 | PGAM2 PGAM1 PGAM4 | purine ribonucleoside diphosphate metabolic process |
| GO:0009135 | 0.0138131421388 | 1.0 | PGAM2 PGAM1 PGAM4 | purine nucleoside diphosphate metabolic process |
| REAC:R-HSA-70171 | 0.0143204798819 | 0.666666666667 | PGAM1 PGAM2 | Glycolysis |
| GO:0009185 | 0.0146853637429 | 1.0 | PGAM2 PGAM1 PGAM4 | ribonucleoside diphosphate metabolic process |
| GO:0006165 | 0.0151349156943 | 1.0 | PGAM2 PGAM1 PGAM4 | nucleoside diphosphate phosphorylation |
| MIRNA:hsa-miR-6733-3p | 0.0155057401397 | 0.666666666667 | PGAM1 PGAM4 | hsa-miR-6733-3p |
| GO:0046939 | 0.0155935495032 | 1.0 | PGAM2 PGAM1 PGAM4 | nucleotide phosphorylation |
| GO:0009132 | 0.0180261250619 | 1.0 | PGAM2 PGAM1 PGAM4 | nucleoside diphosphate metabolic process |
| MIRNA:hsa-miR-4504 | 0.0196579207039 | 0.666666666667 | PGAM1 PGAM4 | hsa-miR-4504 |
| REAC:R-HSA-70326 | 0.022155781492 | 0.666666666667 | PGAM1 PGAM2 | Glucose metabolism |
| MIRNA:hsa-miR-4448 | 0.0229240616855 | 0.666666666667 | PGAM1 PGAM4 | hsa-miR-4448 |
| MIRNA:hsa-miR-4268 | 0.0236073020324 | 0.666666666667 | PGAM1 PGAM4 | hsa-miR-4268 |
| GO:0016853 | 0.0236246361809 | 1.0 | PGAM2 PGAM1 PGAM4 | isomerase activity |
| GO:0006090 | 0.0288576025313 | 1.0 | PGAM2 PGAM1 PGAM4 | pyruvate metabolic process |
| MIRNA:hsa-miR-7845-5p | 0.0358983465251 | 0.666666666667 | PGAM1 PGAM4 | hsa-miR-7845-5p |
| MIRNA:hsa-miR-657 | 0.0376144665371 | 0.666666666667 | PGAM1 PGAM4 | hsa-miR-657 |
| MIRNA:hsa-miR-3126-5p | 0.0384874919534 | 0.666666666667 | PGAM1 PGAM4 | hsa-miR-3126-5p |
| MIRNA:hsa-miR-6875-5p | 0.0384874919534 | 0.666666666667 | PGAM1 PGAM4 | hsa-miR-6875-5p |
| MIRNA:hsa-miR-4688 | 0.0430022189176 | 0.666666666667 | PGAM1 PGAM4 | hsa-miR-4688 |
| MIRNA:hsa-miR-6743-5p | 0.0430022189176 | 0.666666666667 | PGAM1 PGAM4 | hsa-miR-6743-5p |
| MIRNA:hsa-miR-6801-5p | 0.049741469638 | 0.666666666667 | PGAM1 PGAM4 | hsa-miR-6801-5p |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PGAM4 | PGAM2 | 1.0 | 0.949 | bioplex (PGAM2) bioplex_WMM |
| PGAM1 | PGAM2 | 0.424 | 0.574 | bioplex (PGAM2) bioplex_WMM youn_WMM |
| PGAM1 | PGAM4 | 0.009 | 0.109 | bioplex_WMM youn_WMM WMM_only |
Images
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Complex HuMAP2_00164 has an average edge precision of 0.544 which is ranked 2240 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PGAM1 | HuMAP2_00164 HuMAP2_03705 |
| PGAM4 | HuMAP2_00164 HuMAP2_01140 HuMAP2_03705 |
| PGAM2 | HuMAP2_00164 HuMAP2_01140 HuMAP2_03705 |