hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00168
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PRKAA2 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) | UniProt NCBI |
| PRKAB1 | 5'-AMP-activated protein kinase subunit beta-1 (AMPK subunit beta-1) (AMPKb) | UniProt NCBI |
| PRKAA1 | 5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26) | UniProt NCBI |
| PRKAB2 | 5'-AMP-activated protein kinase subunit beta-2 (AMPK subunit beta-2) | UniProt NCBI |
| PRKAG1 | 5'-AMP-activated protein kinase subunit gamma-1 (AMPK gamma1) (AMPK subunit gamma-1) (AMPKg) | UniProt NCBI |
| PRKAG2 | 5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma2) (AMPK subunit gamma-2) (H91620p) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP3965 | 1.02784636904e-15 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Lipid Metabolism Pathway |
| KEGG:04710 | 1.45197782164e-15 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Circadian rhythm |
| REAC:R-HSA-9619483 | 1.45681416991e-15 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Activation of AMPK downstream of NMDARs |
| REAC:R-HSA-380972 | 4.0776855952e-15 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Energy dependent regulation of mTOR by LKB1-AMPK |
| WP:WP1471 | 4.42840981146e-15 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Target Of Rapamycin (TOR) Signaling |
| REAC:R-HSA-9613354 | 9.0230347994e-15 | 0.833333333333 | PRKAG2 PRKAG1 PRKAA2 PRKAB1 PRKAB2 | Lipophagy |
| REAC:R-HSA-2151209 | 2.03006918199e-14 | 0.833333333333 | PRKAG2 PRKAG1 PRKAA2 PRKAB1 PRKAB2 | Activation of PPARGC1A (PGC-1alpha) by phosphorylation |
| WP:WP1541 | 2.22218780766e-14 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Energy Metabolism |
| WP:WP4539 | 2.92949392693e-14 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Synaptic signaling pathways associated with autism spectrum disorder |
| REAC:R-HSA-165159 | 3.53133482234e-14 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | mTOR signalling |
| KEGG:04213 | 9.92451875191e-14 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Longevity regulating pathway - multiple species |
| WP:WP1403 | 2.04549906885e-13 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | AMP-activated Protein Kinase (AMPK) Signaling |
| KEGG:04920 | 2.29171654936e-13 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Adipocytokine signaling pathway |
| WP:WP1982 | 2.47886751564e-13 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Sterol Regulatory Element-Binding Proteins (SREBP) signalling |
| GO:0004679 | 2.94892899195e-13 | 0.833333333333 | PRKAA1 PRKAG1 PRKAA2 PRKAB1 PRKAB2 | AMP-activated protein kinase activity |
| REAC:R-HSA-9613829 | 4.83670638587e-13 | 0.833333333333 | PRKAG2 PRKAG1 PRKAA2 PRKAB1 PRKAB2 | Chaperone Mediated Autophagy |
| KEGG:05410 | 9.92011275025e-13 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Hypertrophic cardiomyopathy (HCM) |
| KEGG:04211 | 1.07032795463e-12 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Longevity regulating pathway |
| WP:WP4540 | 1.37772277124e-12 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Pathways Regulating Hippo Signaling |
| REAC:R-HSA-438064 | 1.84250746399e-12 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Post NMDA receptor activation events |
| GO:0031588 | 2.75202561382e-12 | 0.833333333333 | PRKAA1 PRKAG2 PRKAG1 PRKAB1 PRKAB2 | nucleotide-activated protein kinase complex |
| KEGG:04922 | 2.83367769146e-12 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Glucagon signaling pathway |
| WP:WP4321 | 3.2522342492e-12 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Thermogenesis |
| REAC:R-HSA-5628897 | 3.25249598369e-12 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | TP53 Regulates Metabolic Genes |
| KEGG:04931 | 4.11595048069e-12 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Insulin resistance |
| REAC:R-HSA-442755 | 4.39959637066e-12 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Activation of NMDA receptors and postsynaptic events |
| REAC:R-HSA-1632852 | 5.46571984656e-12 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Macroautophagy |
| REAC:R-HSA-6804756 | 7.21462548483e-12 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Regulation of TP53 Activity through Phosphorylation |
| KEGG:04152 | 7.31279347995e-12 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | AMPK signaling pathway |
| KEGG:04068 | 8.15190425828e-12 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | FoxO signaling pathway |
| WP:WP3915 | 1.21829982323e-11 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Angiopoietin Like Protein 8 Regulatory Pathway |
| REAC:R-HSA-9615710 | 1.29938364124e-11 | 0.833333333333 | PRKAG2 PRKAG1 PRKAA2 PRKAB1 PRKAB2 | Microautophagy |
| KEGG:04371 | 1.36494702417e-11 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Apelin signaling pathway |
| KEGG:04910 | 1.43376788254e-11 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Insulin signaling pathway |
| REAC:R-HSA-9612973 | 1.54760294566e-11 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Autophagy |
| KEGG:04932 | 2.09582729009e-11 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Non-alcoholic fatty liver disease (NAFLD) |
| WP:WP4396 | 2.24221674056e-11 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Nonalcoholic fatty liver disease |
| KEGG:04921 | 2.29611892429e-11 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Oxytocin signaling pathway |
| KEGG:04530 | 3.5531833266e-11 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Tight junction |
| REAC:R-HSA-5633007 | 2.04386024198e-10 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Regulation of TP53 Activity |
| KEGG:04714 | 3.29114340615e-10 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Thermogenesis |
| REAC:R-HSA-112314 | 3.95955505487e-10 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Neurotransmitter receptors and postsynaptic signal transmission |
| REAC:R-HSA-1445148 | 1.67395276865e-09 | 0.833333333333 | PRKAG2 PRKAG1 PRKAA2 PRKAB1 PRKAB2 | Translocation of SLC2A4 (GLUT4) to the plasma membrane |
| REAC:R-HSA-112315 | 1.92425302259e-09 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Transmission across Chemical Synapses |
| CORUM:6155 | 2.25356268047e-09 | 0.5 | PRKAG1 PRKAB2 PRKAA2 | PRKAA2-PRKAB2-PRKAG1 complex |
| CORUM:6154 | 2.25356268047e-09 | 0.5 | PRKAG1 PRKAB2 PRKAA1 | PRKAA1-PRKAB2-PRKAG1 complex |
| REAC:R-HSA-1592230 | 6.28394919001e-09 | 0.833333333333 | PRKAG2 PRKAG1 PRKAA2 PRKAB1 PRKAB2 | Mitochondrial biogenesis |
| REAC:R-HSA-112316 | 2.26130102665e-08 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Neuronal System |
| REAC:R-HSA-3700989 | 2.55679543571e-08 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Transcriptional Regulation by TP53 |
| GO:0016241 | 3.67864745509e-08 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | regulation of macroautophagy |
| GO:1901796 | 7.26714234825e-08 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | regulation of signal transduction by p53 class mediator |
| WP:WP3934 | 1.25980927307e-07 | 0.5 | PRKAG1 PRKAB1 PRKAA1 | Leptin and adiponectin |
| GO:0007050 | 1.92887063772e-07 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | cell cycle arrest |
| REAC:R-HSA-8953897 | 1.96860593734e-07 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Cellular responses to external stimuli |
| REAC:R-HSA-163680 | 3.33245821776e-07 | 0.5 | PRKAG2 PRKAB2 PRKAA2 | AMPK inhibits chREBP transcriptional activation activity |
| GO:0072331 | 6.5250491608e-07 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | signal transduction by p53 class mediator |
| CORUM:6888 | 8.18934150988e-07 | 0.5 | PRKAG1 PRKAB1 PRKAA1 | v-ATPase-Ragulator-AXIN/LKB1-AMPK complex |
| GO:0016236 | 1.21660050468e-06 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | macroautophagy |
| GO:0010506 | 1.43261571772e-06 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | regulation of autophagy |
| REAC:R-HSA-200425 | 1.70064822019e-06 | 0.5 | PRKAG2 PRKAB2 PRKAA2 | Import of palmitoyl-CoA into the mitochondrial matrix |
| WP:WP4206 | 1.70690021658e-06 | 0.5 | PRKAG1 PRKAB1 PRKAA1 | Hereditary leiomyomatosis and renal cell carcinoma pathway |
| GO:1902911 | 1.91660450295e-06 | 0.833333333333 | PRKAA1 PRKAG2 PRKAG1 PRKAB1 PRKAB2 | protein kinase complex |
| REAC:R-HSA-1852241 | 2.15632898754e-06 | 0.833333333333 | PRKAG2 PRKAG1 PRKAA2 PRKAB1 PRKAB2 | Organelle biogenesis and maintenance |
| GO:0006914 | 1.67630347668e-05 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | autophagy |
| GO:0061919 | 1.67630347668e-05 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | process utilizing autophagic mechanism |
| REAC:R-HSA-212436 | 1.81072012887e-05 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Generic Transcription Pathway |
| CORUM:6153 | 2.51655344529e-05 | 0.333333333333 | PRKAB2 PRKAA2 | PRKAA2-PRKAB2-PRKAG3 complex |
| REAC:R-HSA-73857 | 3.48623271686e-05 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | RNA Polymerase II Transcription |
| GO:0045786 | 6.38495178057e-05 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | negative regulation of cell cycle |
| REAC:R-HSA-74160 | 6.720667947e-05 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Gene expression (Transcription) |
| REAC:R-HSA-199991 | 8.45689503243e-05 | 0.833333333333 | PRKAG2 PRKAG1 PRKAA2 PRKAB1 PRKAB2 | Membrane Trafficking |
| REAC:R-HSA-5653656 | 0.000110463892332 | 0.833333333333 | PRKAG2 PRKAG1 PRKAA2 PRKAB1 PRKAB2 | Vesicle-mediated transport |
| GO:0061695 | 0.000213275731053 | 0.833333333333 | PRKAA1 PRKAG2 PRKAG1 PRKAB1 PRKAB2 | transferase complex, transferring phosphorus-containing groups |
| GO:0006853 | 0.000217734118711 | 0.5 | PRKAG2 PRKAB2 PRKAA2 | carnitine shuttle |
| GO:0006110 | 0.000231008761032 | 0.666666666667 | PRKAG2 PRKAG1 PRKAA1 PRKAA2 | regulation of glycolytic process |
| GO:0043470 | 0.000314144203038 | 0.666666666667 | PRKAG2 PRKAG1 PRKAA1 PRKAA2 | regulation of carbohydrate catabolic process |
| GO:0031329 | 0.000416604145217 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | regulation of cellular catabolic process |
| GO:1900542 | 0.000770248195723 | 0.666666666667 | PRKAG2 PRKAG1 PRKAA1 PRKAA2 | regulation of purine nucleotide metabolic process |
| GO:0006140 | 0.00084563217517 | 0.666666666667 | PRKAG2 PRKAG1 PRKAA1 PRKAA2 | regulation of nucleotide metabolic process |
| REAC:R-HSA-162582 | 0.000858808853527 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | Signal Transduction |
| REAC:R-HSA-163685 | 0.000865642910945 | 0.5 | PRKAG2 PRKAB2 PRKAA2 | Integration of energy metabolism |
| GO:0062012 | 0.00096257047912 | 0.833333333333 | PRKAG2 PRKAG1 PRKAA2 PRKAB2 PRKAA1 | regulation of small molecule metabolic process |
| GO:1903578 | 0.00101282970404 | 0.666666666667 | PRKAG2 PRKAG1 PRKAA1 PRKAA2 | regulation of ATP metabolic process |
| GO:1902001 | 0.00101517134288 | 0.5 | PRKAG2 PRKAB2 PRKAA2 | fatty acid transmembrane transport |
| GO:0009894 | 0.00102856042316 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | regulation of catabolic process |
| GO:0006096 | 0.001058235898 | 0.666666666667 | PRKAG2 PRKAG1 PRKAA1 PRKAA2 | glycolytic process |
| GO:0006757 | 0.00110514929169 | 0.666666666667 | PRKAG2 PRKAG1 PRKAA1 PRKAA2 | ATP generation from ADP |
| GO:0046031 | 0.00120362941431 | 0.666666666667 | PRKAG2 PRKAG1 PRKAA1 PRKAA2 | ADP metabolic process |
| GO:0009179 | 0.00130853702278 | 0.666666666667 | PRKAG2 PRKAG1 PRKAA1 PRKAA2 | purine ribonucleoside diphosphate metabolic process |
| GO:0009135 | 0.00130853702278 | 0.666666666667 | PRKAG2 PRKAG1 PRKAA1 PRKAA2 | purine nucleoside diphosphate metabolic process |
| GO:0009185 | 0.00142014462948 | 0.666666666667 | PRKAG2 PRKAG1 PRKAA1 PRKAA2 | ribonucleoside diphosphate metabolic process |
| GO:0006165 | 0.00147854761151 | 0.666666666667 | PRKAG2 PRKAG1 PRKAA1 PRKAA2 | nucleoside diphosphate phosphorylation |
| GO:0046939 | 0.00153873030218 | 0.666666666667 | PRKAG2 PRKAG1 PRKAA1 PRKAA2 | nucleotide phosphorylation |
| GO:0009132 | 0.00186759839818 | 0.666666666667 | PRKAG2 PRKAG1 PRKAA1 PRKAA2 | nucleoside diphosphate metabolic process |
| GO:0051726 | 0.0023963010185 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | regulation of cell cycle |
| GO:0004674 | 0.00259964787746 | 0.833333333333 | PRKAA1 PRKAG1 PRKAA2 PRKAB1 PRKAB2 | protein serine/threonine kinase activity |
| GO:0043467 | 0.0028699930952 | 0.666666666667 | PRKAG2 PRKAG1 PRKAA1 PRKAA2 | regulation of generation of precursor metabolites and energy |
| REAC:R-HSA-8978868 | 0.00340713657136 | 0.5 | PRKAG2 PRKAB2 PRKAA2 | Fatty acid metabolism |
| GO:0006090 | 0.00350044252869 | 0.666666666667 | PRKAG2 PRKAG1 PRKAA1 PRKAA2 | pyruvate metabolic process |
| GO:0046890 | 0.00436089686659 | 0.666666666667 | PRKAG2 PRKAA2 PRKAB2 PRKAA1 | regulation of lipid biosynthetic process |
| GO:0006109 | 0.00477442110408 | 0.666666666667 | PRKAG2 PRKAG1 PRKAA1 PRKAA2 | regulation of carbohydrate metabolic process |
| GO:0022402 | 0.00779587445301 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | cell cycle process |
| GO:0016052 | 0.00811327342942 | 0.666666666667 | PRKAG2 PRKAG1 PRKAA1 PRKAA2 | carbohydrate catabolic process |
| GO:0042304 | 0.00813009778332 | 0.5 | PRKAG2 PRKAB2 PRKAA2 | regulation of fatty acid biosynthetic process |
| WP:WP4286 | 0.00883210845165 | 0.333333333333 | PRKAB1 PRKAB2 | Genotoxicity pathway |
| GO:0032787 | 0.00974381439214 | 0.833333333333 | PRKAG2 PRKAG1 PRKAA2 PRKAB2 PRKAA1 | monocarboxylic acid metabolic process |
| GO:0004672 | 0.0119564905365 | 0.833333333333 | PRKAA1 PRKAG1 PRKAA2 PRKAB1 PRKAB2 | protein kinase activity |
| WP:WP2034 | 0.014901555017 | 0.333333333333 | PRKAA1 PRKAA2 | Leptin signaling pathway |
| GO:0032365 | 0.0165096938447 | 0.5 | PRKAG2 PRKAB2 PRKAA2 | intracellular lipid transport |
| GO:0015909 | 0.0165096938447 | 0.5 | PRKAG2 PRKAB2 PRKAA2 | long-chain fatty acid transport |
| GO:1904428 | 0.020283420769 | 0.333333333333 | PRKAA1 PRKAA2 | negative regulation of tubulin deacetylation |
| GO:1902531 | 0.0206904307747 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | regulation of intracellular signal transduction |
| GO:0007049 | 0.0218766736595 | 1.0 | PRKAA1 PRKAG2 PRKAB1 PRKAB2 PRKAG1 PRKAA2 | cell cycle |
| GO:0016773 | 0.0278470167072 | 0.833333333333 | PRKAA1 PRKAG1 PRKAA2 PRKAB1 PRKAB2 | phosphotransferase activity, alcohol group as acceptor |
| GO:0015908 | 0.0398453744123 | 0.5 | PRKAG2 PRKAB2 PRKAA2 | fatty acid transport |
| GO:0016301 | 0.0424115510531 | 0.833333333333 | PRKAA1 PRKAG1 PRKAA2 PRKAB1 PRKAB2 | kinase activity |
| GO:0046034 | 0.0457293961323 | 0.666666666667 | PRKAG2 PRKAG1 PRKAA1 PRKAA2 | ATP metabolic process |
| KEGG:05418 | 0.0474671394747 | 0.333333333333 | PRKAA1 PRKAA2 | Fluid shear stress and atherosclerosis |
| GO:0019217 | 0.0499477329172 | 0.5 | PRKAG2 PRKAB2 PRKAA2 | regulation of fatty acid metabolic process |
| CORUM:771 | 0.0499726005494 | 0.166666666667 | PRKAA1 | NDPKA-AMPKalpha1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PRKAA1 | PRKAG1 | 1.0 | 0.949 | hein_WMM bioplex (PRKAG1) bioplex_WMM youn_WMM hein (PRKAA1) gupta_WMM boldt_WMM |
| PRKAB1 | PRKAG1 | 1.0 | 0.949 | hein_WMM bioplex (PRKAB1,PRKAG1) bioplex_WMM youn_WMM gupta_WMM |
| PRKAA2 | PRKAG1 | 0.999 | 0.949 | bioplex (PRKAG1) bioplex_WMM youn_WMM gupta_WMM |
| PRKAB2 | PRKAG1 | 0.998 | 0.944 | hein_WMM bioplex (PRKAB2,PRKAG1) bioplex_WMM |
| PRKAB2 | PRKAA1 | 0.993 | 0.918 | hein_WMM bioplex (PRKAB2) bioplex_WMM Guru hein (PRKAA1) fraction |
| PRKAB1 | PRKAG2 | 0.976 | 0.892 | bioplex (PRKAB1,PRKAG2) bioplex_WMM youn_WMM gupta_WMM |
| PRKAB1 | PRKAA1 | 0.925 | 0.843 | hein_WMM bioplex (PRKAB1) bioplex_WMM Guru youn_WMM hein (PRKAA1) gupta_WMM fraction |
| PRKAB2 | PRKAG2 | 0.876 | 0.81 | bioplex (PRKAB2,PRKAG2) bioplex_WMM |
| PRKAA1 | PRKAG2 | 0.69 | 0.715 | bioplex (PRKAG2) bioplex_WMM youn_WMM gupta_WMM |
| PRKAA2 | PRKAG2 | 0.649 | 0.687 | bioplex (PRKAG2) bioplex_WMM |
| PRKAB1 | PRKAA2 | 0.478 | 0.611 | bioplex (PRKAB1) bioplex_WMM Guru youn_WMM gupta_WMM fraction |
| PRKAB2 | PRKAA2 | 0.238 | 0.47 | bioplex (PRKAB2) bioplex_WMM |
| PRKAB1 | PRKAB2 | 0.215 | 0.464 | hein_WMM bioplex (PRKAB1) bioplex_WMM |
| PRKAA1 | PRKAA2 | 0.019 | 0.185 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| PRKAG1 | PRKAG2 | 0.012 | 0.146 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_00168 has an average edge precision of 0.702 which is ranked 1361 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PRKAA2 | HuMAP2_00168 HuMAP2_02825 HuMAP2_03872 HuMAP2_05529 |
| PRKAB1 | HuMAP2_00168 HuMAP2_02825 HuMAP2_03872 |
| PRKAA1 | HuMAP2_00168 HuMAP2_02825 HuMAP2_03872 HuMAP2_05529 |
| PRKAB2 | HuMAP2_00168 HuMAP2_02825 HuMAP2_03872 |
| PRKAG1 | HuMAP2_00168 HuMAP2_02825 HuMAP2_03872 HuMAP2_05529 |
| PRKAG2 | HuMAP2_00168 HuMAP2_02825 HuMAP2_03872 |