hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00179
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MTAP | S-methyl-5'-thioadenosine phosphorylase (EC 2.4.2.28) (5'-methylthioadenosine phosphorylase) (MTA phosphorylase) (MTAP) (MTAPase) | UniProt NCBI |
| SUCLA2 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial (EC 6.2.1.5) (ATP-specific succinyl-CoA synthetase subunit beta) (A-SCS) (Succinyl-CoA synthetase beta-A chain) (SCS-betaA) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4236 | 0.038834152205 | 0.5 | SUCLA2 | Disorders of the Krebs cycle |
| HP:0005010 | 0.0497341708567 | 0.5 | MTAP | Osteomyelitis leading to amputation due to slow healing fractures |
| CORUM:394 | 0.0499173803268 | 0.5 | SUCLA2 | Succinyl-CoA synthetase, ADP-forming |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MTAP | SUCLA2 | 0.137 | 0.406 | bioplex_WMM fraction |
Images
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Complex HuMAP2_00179 has an average edge precision of 0.406 which is ranked 3251 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MTAP | HuMAP2_00179 HuMAP2_05892 |
| SUCLA2 | HuMAP2_00179 HuMAP2_03050 HuMAP2_03427 HuMAP2_04460 HuMAP2_05892 |