hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00182
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| GFM1 | Elongation factor G, mitochondrial (EF-Gmt) (Elongation factor G 1, mitochondrial) (mEF-G 1) (Elongation factor G1) (hEFG1) | UniProt NCBI |
| IDH1 | Isocitrate dehydrogenase [NADP] cytoplasmic (IDH) (EC 1.1.1.42) (Cytosolic NADP-isocitrate dehydrogenase) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase) | UniProt NCBI |
| FAM49B | Protein FAM49B (L1) | UniProt NCBI |
| FAM49A | Protein FAM49A | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:404 | 0.0249595281251 | 0.25 | IDH1 | Isocitrate dehydrogenase [NADP], cytoplasmic |
| REAC:R-HSA-2978092 | 0.0499190562503 | 0.25 | IDH1 | Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate |
| REAC:R-HSA-389542 | 0.0499190562503 | 0.25 | IDH1 | NADPH regeneration |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| FAM49B | FAM49A | 1.0 | 0.949 | bioplex (FAM49B) bioplex_WMM |
| IDH1 | FAM49B | 0.048 | 0.294 | bioplex_WMM fraction treiber_WMM |
| IDH1 | GFM1 | 0.031 | 0.236 | bioplex_WMM fraction |
| FAM49B | GFM1 | 0.007 | 0.007 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_00182 has an average edge precision of 0.371 which is ranked 3622 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| GFM1 | HuMAP2_00182 HuMAP2_01941 HuMAP2_04067 HuMAP2_05526 |
| IDH1 | HuMAP2_00182 HuMAP2_00843 HuMAP2_04319 HuMAP2_05071 HuMAP2_05968 HuMAP2_05984 |
| FAM49B | HuMAP2_00182 HuMAP2_03102 |
| FAM49A | HuMAP2_00182 HuMAP2_03102 |