hu.MAP 2.0: Complex View

Human Protein Complex Map

Complex: HuMAP2_00194

Confidence: Medium

Genename	Protein Name	Links
PXDN	Peroxidasin homolog (EC 1.11.1.7) (Melanoma-associated antigen MG50) (Vascular peroxidase 1) (p53-responsive gene 2 protein)	UniProt NCBI
ERP44	Endoplasmic reticulum resident protein 44 (ER protein 44) (ERp44) (Thioredoxin domain-containing protein 4)	UniProt NCBI
CYB5B	Cytochrome b5 type B (Cytochrome b5 outer mitochondrial membrane isoform)	UniProt NCBI
ZFPM1	Zinc finger protein ZFPM1 (Friend of GATA protein 1) (FOG-1) (Friend of GATA 1) (Zinc finger protein 89A) (Zinc finger protein multitype 1)	UniProt NCBI
FAM53B	Protein FAM53B (Protein simplet)	UniProt NCBI
HOXB6	Homeobox protein Hox-B6 (Homeobox protein Hox-2.2) (Homeobox protein Hox-2B) (Homeobox protein Hu-2)	UniProt NCBI
HOXA6	Homeobox protein Hox-A6 (Homeobox protein Hox-1B)	UniProt NCBI
MEX3A	RNA-binding protein MEX3A (RING finger and KH domain-containing protein 4)	UniProt NCBI
ITPKC	Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5-trisphosphate 3-kinase C) (IP3 3-kinase C) (IP3K C) (InsP 3-kinase C)	UniProt NCBI
NOMO1	Nodal modulator 1 (pM5 protein)	UniProt NCBI
MEN1	Menin	UniProt NCBI
FIGN	Fidgetin	UniProt NCBI
NOMO2	Nodal modulator 2 (pM5 protein 2)	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
HPA:041010_23	0.00192131518913	0.384615384615	NOMO2 HOXA6 NOMO1 FIGN FAM53B	skeletal muscle; myocytes[Approved,High]
HPA:008020_22	0.00578230852775	0.538461538462	NOMO2 FIGN ITPKC HOXA6 NOMO1 FAM53B CYB5B	cerebral cortex; glial cells[Approved,Medium]
HPA:048030_22	0.0151890782348	0.538461538462	NOMO2 FIGN ITPKC HOXA6 NOMO1 FAM53B CYB5B	soft tissue 2; fibroblasts[Approved,Medium]
HPA:004010_21	0.0161197158337	0.538461538462	NOMO2 FIGN ITPKC HOXA6 NOMO1 FAM53B CYB5B	breast; adipocytes[Approved,Low]
HPA:027020_22	0.0164154184442	0.538461538462	NOMO2 CYB5B FIGN HOXA6 PXDN FAM53B NOMO1	lung; pneumocytes[Approved,Medium]
HPA:056020_22	0.0165336075641	0.615384615385	NOMO2 FIGN ITPKC HOXA6 NOMO1 PXDN FAM53B CYB5B	tonsil; non-germinal center cells[Approved,Medium]
HPA:009010_22	0.0243218708837	0.615384615385	NOMO2 FIGN ITPKC HOXA6 NOMO1 PXDN FAM53B CYB5B	cervix, uterine; glandular cells[Approved,Medium]
HPA:006010_21	0.0444903698268	0.615384615385	NOMO2 FIGN ITPKC HOXA6 NOMO1 PXDN FAM53B CYB5B	caudate; glial cells[Approved,Low]

Edges

Protein 1	Protein 2	Score	Precision	Evidence
ERP44	FAM53B	0.76	0.749	bioplex (ERP44) bioplex_WMM
ERP44	ZFPM1	0.516	0.631	bioplex (ERP44) bioplex_WMM
ERP44	ITPKC	0.489	0.618	bioplex (ERP44) bioplex_WMM
ERP44	HOXA6	0.273	0.486	bioplex (ERP44) bioplex_WMM
ERP44	FIGN	0.082	0.351	bioplex (ERP44) bioplex_WMM
ERP44	MEX3A	0.077	0.352	bioplex (ERP44) bioplex_WMM
ERP44	CYB5B	0.072	0.356	bioplex_WMM fraction
ERP44	MEN1	0.036	0.264	hein_WMM bioplex_WMM hein (ERP44) fraction
ERP44	PXDN	0.034	0.261	bioplex (ERP44) bioplex_WMM
ERP44	HOXB6	0.026	0.224	bioplex (ERP44) bioplex_WMM
ERP44	NOMO2	0.026	0.215	gupta_WMM fraction
ERP44	NOMO1	0.022	0.205	bioplex_WMM fraction
FAM53B	HOXA6	0.009	0.095	bioplex_WMM WMM_only
FAM53B	ITPKC	0.008	0.091	bioplex_WMM WMM_only
HOXA6	ITPKC	0.008	0.091	bioplex_WMM WMM_only
FAM53B	FIGN	0.008	0.091	bioplex_WMM WMM_only
FIGN	HOXA6	0.008	0.091	bioplex_WMM WMM_only
HOXA6	MEX3A	0.008	0.091	bioplex_WMM WMM_only
FAM53B	MEX3A	0.008	0.091	bioplex_WMM WMM_only
FAM53B	ZFPM1	0.008	0.087	bioplex_WMM WMM_only
ZFPM1	HOXA6	0.008	0.087	bioplex_WMM WMM_only
FAM53B	HOXB6	0.008	0.085	bioplex_WMM WMM_only
HOXB6	HOXA6	0.008	0.085	bioplex_WMM WMM_only
FIGN	ITPKC	0.008	0.085	bioplex_WMM WMM_only
MEX3A	ITPKC	0.008	0.085	bioplex_WMM WMM_only
FIGN	MEX3A	0.008	0.085	bioplex_WMM WMM_only
ZFPM1	ITPKC	0.008	0.067	bioplex_WMM WMM_only
ZFPM1	MEX3A	0.008	0.067	bioplex_WMM WMM_only
ZFPM1	FIGN	0.008	0.067	bioplex_WMM WMM_only
HOXB6	MEX3A	0.008	0.062	bioplex_WMM youn_WMM WMM_only
FIGN	HOXB6	0.008	0.06	bioplex_WMM WMM_only
HOXB6	ITPKC	0.008	0.06	bioplex_WMM WMM_only
ZFPM1	HOXB6	0.008	0.04	bioplex_WMM WMM_only
FAM53B	PXDN	0.008	0.011	bioplex_WMM WMM_only
HOXA6	PXDN	0.008	0.011	bioplex_WMM WMM_only
MEX3A	PXDN	0.007	0.01	bioplex_WMM youn_WMM WMM_only
ITPKC	PXDN	0.007	0.006	bioplex_WMM WMM_only
FIGN	PXDN	0.007	0.006	bioplex_WMM WMM_only
ZFPM1	PXDN	0.007	0.004	bioplex_WMM WMM_only
NOMO1	MEN1	0.007	0.004	bioplex_WMM WMM_only
HOXB6	PXDN	0.007	0.004	bioplex_WMM WMM_only
FIGN	MEN1	0.007	0.002	youn_WMM WMM_only
CYB5B	PXDN	0.007	0.002	bioplex_WMM WMM_only
MEX3A	MEN1	0.007	0.001	youn_WMM WMM_only
HOXB6	MEN1	0.007	0.001	youn_WMM WMM_only
ZFPM1	NOMO1	0.007	0.002	bioplex_WMM WMM_only
NOMO2	NOMO1	0.007	0.006	gupta_WMM WMM_only
CYB5B	MEN1	0.007	0.002	bioplex_WMM WMM_only
CYB5B	NOMO1	0.007	0.003	bioplex_WMM WMM_only
MEN1	PXDN	0.006	0.004	bioplex_WMM youn_WMM WMM_only
NOMO1	PXDN	0.004	0.011	bioplex_WMM WMM_only

Images

Click to enlarge

Complex HuMAP2_00194 has an average edge precision of 0.127 which is ranked 6842 out of all 6965 complexes.

Related Complexes

Genename	Complexes
PXDN	HuMAP2_00194 HuMAP2_01490 HuMAP2_05858
ERP44	HuMAP2_00080 HuMAP2_00194 HuMAP2_03232 HuMAP2_06926
CYB5B	HuMAP2_00194 HuMAP2_04911
ZFPM1	HuMAP2_00080 HuMAP2_00194 HuMAP2_02872 HuMAP2_04225
FAM53B	HuMAP2_00080 HuMAP2_00194 HuMAP2_06926
HOXB6	HuMAP2_00194 HuMAP2_00529 HuMAP2_01087 HuMAP2_07016
HOXA6	HuMAP2_00194
MEX3A	HuMAP2_00194 HuMAP2_04286 HuMAP2_04916 HuMAP2_05952
ITPKC	HuMAP2_00194 HuMAP2_02352 HuMAP2_03018
NOMO1	HuMAP2_00194 HuMAP2_03276 HuMAP2_04431
MEN1	HuMAP2_00194
FIGN	HuMAP2_00108 HuMAP2_00194 HuMAP2_02436 HuMAP2_04945
NOMO2	HuMAP2_00194

hu.MAP 2.0: Complex View

Search for a protein

Complex: HuMAP2_00194