hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00215
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RPL10 | 60S ribosomal protein L10 (Laminin receptor homolog) (Large ribosomal subunit protein uL16) (Protein QM) (Ribosomal protein L10) (Tumor suppressor QM) | UniProt NCBI |
| SLC25A5 | ADP/ATP translocase 2 (ADP,ATP carrier protein 2) (ADP,ATP carrier protein, fibroblast isoform) (Adenine nucleotide translocator 2) (ANT 2) (Solute carrier family 25 member 5) [Cleaved into: ADP/ATP translocase 2, N-terminally processed] | UniProt NCBI |
| RPS17 | 40S ribosomal protein S17 (Small ribosomal subunit protein eS17) | UniProt NCBI |
| RPL29 | 60S ribosomal protein L29 (Cell surface heparin-binding protein HIP) (Large ribosomal subunit protein eL29) | UniProt NCBI |
| AAMP | Angio-associated migratory cell protein | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:3055 | 7.67298453472e-07 | 0.8 | RPL29 RPS17 SLC25A5 RPL10 | Nop56p-associated pre-rRNA complex |
| WP:WP477 | 7.07040269841e-05 | 0.6 | RPL29 RPS17 RPL10 | Cytoplasmic Ribosomal Proteins |
| CORUM:306 | 0.000106056122258 | 0.6 | RPL29 RPS17 RPL10 | Ribosome, cytoplasmic |
| REAC:R-HSA-5663205 | 0.000241108816086 | 0.8 | RPL29 RPS17 SLC25A5 RPL10 | Infectious disease |
| REAC:R-HSA-192823 | 0.000295836172608 | 0.6 | RPL29 RPS17 RPL10 | Viral mRNA Translation |
| REAC:R-HSA-156902 | 0.000295836172608 | 0.6 | RPL29 RPS17 RPL10 | Peptide chain elongation |
| KEGG:03010 | 0.000305495250573 | 0.6 | RPL29 RPS17 RPL10 | Ribosome |
| REAC:R-HSA-72764 | 0.000338412904811 | 0.6 | RPL29 RPS17 RPL10 | Eukaryotic Translation Termination |
| REAC:R-HSA-2408557 | 0.000338412904811 | 0.6 | RPL29 RPS17 RPL10 | Selenocysteine synthesis |
| REAC:R-HSA-156842 | 0.000338412904811 | 0.6 | RPL29 RPS17 RPL10 | Eukaryotic Translation Elongation |
| REAC:R-HSA-975956 | 0.000361148609859 | 0.6 | RPL29 RPS17 RPL10 | Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) |
| REAC:R-HSA-72689 | 0.000435396498961 | 0.6 | RPL29 RPS17 RPL10 | Formation of a pool of free 40S subunits |
| REAC:R-HSA-156827 | 0.000580533129267 | 0.6 | RPL29 RPS17 RPL10 | L13a-mediated translational silencing of Ceruloplasmin expression |
| REAC:R-HSA-72706 | 0.000596598643168 | 0.6 | RPL29 RPS17 RPL10 | GTP hydrolysis and joining of the 60S ribosomal subunit |
| REAC:R-HSA-1799339 | 0.000596598643168 | 0.6 | RPL29 RPS17 RPL10 | SRP-dependent cotranslational protein targeting to membrane |
| REAC:R-HSA-927802 | 0.00062960997049 | 0.6 | RPL29 RPS17 RPL10 | Nonsense-Mediated Decay (NMD) |
| REAC:R-HSA-975957 | 0.00062960997049 | 0.6 | RPL29 RPS17 RPL10 | Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) |
| REAC:R-HSA-2408522 | 0.000646560981801 | 0.6 | RPL29 RPS17 RPL10 | Selenoamino acid metabolism |
| REAC:R-HSA-72737 | 0.000717394603045 | 0.6 | RPL29 RPS17 RPL10 | Cap-dependent Translation Initiation |
| REAC:R-HSA-72613 | 0.000717394603045 | 0.6 | RPL29 RPS17 RPL10 | Eukaryotic Translation Initiation |
| REAC:R-HSA-168273 | 0.000960389260783 | 0.6 | RPL29 RPS17 RPL10 | Influenza Viral RNA Transcription and Replication |
| REAC:R-HSA-168255 | 0.00114945154681 | 0.6 | RPL29 RPS17 RPL10 | Influenza Life Cycle |
| REAC:R-HSA-168254 | 0.00141854667829 | 0.6 | RPL29 RPS17 RPL10 | Influenza Infection |
| REAC:R-HSA-9010553 | 0.00207569805025 | 0.6 | RPL29 RPS17 RPL10 | Regulation of expression of SLITs and ROBOs |
| REAC:R-HSA-6791226 | 0.00259573944873 | 0.6 | RPL29 RPS17 RPL10 | Major pathway of rRNA processing in the nucleolus and cytosol |
| REAC:R-HSA-8868773 | 0.00304975168622 | 0.6 | RPL29 RPS17 RPL10 | rRNA processing in the nucleus and cytosol |
| REAC:R-HSA-72312 | 0.00355347569673 | 0.6 | RPL29 RPS17 RPL10 | rRNA processing |
| REAC:R-HSA-376176 | 0.00422709568106 | 0.6 | RPL29 RPS17 RPL10 | Signaling by ROBO receptors |
| CORUM:308 | 0.00690254383634 | 0.4 | RPL29 RPL10 | 60S ribosomal subunit, cytoplasmic |
| REAC:R-HSA-72766 | 0.0106248808855 | 0.6 | RPL29 RPS17 RPL10 | Translation |
| REAC:R-HSA-1643685 | 0.0116415059931 | 0.8 | RPL29 RPS17 SLC25A5 RPL10 | Disease |
| REAC:R-HSA-71291 | 0.0184395275066 | 0.6 | RPL29 RPS17 RPL10 | Metabolism of amino acids and derivatives |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RPL10 | RPS17 | 0.848 | 0.79 | hein_WMM bioplex_WMM boldt hein (RPL10) gupta_WMM boldt_WMM treiber_WMM |
| AAMP | RPL10 | 0.79 | 0.758 | hein_WMM bioplex (AAMP) bioplex_WMM boldt hein (RPL10) boldt_WMM |
| RPL29 | RPL10 | 0.61 | 0.674 | hein_WMM bioplex_WMM boldt hein (RPL10) gupta_WMM boldt_WMM treiber_WMM |
| SLC25A5 | RPL10 | 0.522 | 0.634 | bioplex (SLC25A5) bioplex_WMM boldt fraction boldt_WMM treiber_WMM |
| RPL29 | RPS17 | 0.014 | 0.144 | hein_WMM bioplex_WMM boldt gupta_WMM boldt_WMM treiber_WMM |
| SLC25A5 | AAMP | 0.008 | 0.011 | bioplex (AAMP) bioplex_WMM boldt boldt_WMM |
| AAMP | RPS17 | 0.007 | 0.011 | hein_WMM bioplex_WMM WMM_only |
| RPL29 | SLC25A5 | 0.007 | 0.007 | boldt boldt_WMM treiber_WMM |
| SLC25A5 | RPS17 | 0.006 | 0.008 | bioplex (SLC25A5) bioplex_WMM boldt boldt_WMM treiber_WMM |
| RPL29 | AAMP | 0.0 | 0.0 | hein_WMM bioplex (AAMP) bioplex_WMM fraction |
Images
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Complex HuMAP2_00215 has an average edge precision of 0.304 which is ranked 4527 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RPL10 | HuMAP2_00215 HuMAP2_00608 HuMAP2_01734 HuMAP2_02207 HuMAP2_04712 HuMAP2_05622 |
| SLC25A5 | HuMAP2_00215 HuMAP2_01502 HuMAP2_03081 HuMAP2_03991 HuMAP2_04721 HuMAP2_04908 HuMAP2_05807 HuMAP2_05840 |
| RPS17 | HuMAP2_00215 HuMAP2_00608 HuMAP2_00945 |
| RPL29 | HuMAP2_00215 HuMAP2_02207 |
| AAMP | HuMAP2_00215 HuMAP2_00834 HuMAP2_01734 HuMAP2_04712 HuMAP2_04980 |