hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00235
Confidence: Medium High  
ProteinsGenename | Protein Name | Links |
---|---|---|
SRP68 | Signal recognition particle subunit SRP68 (SRP68) (Signal recognition particle 68 kDa protein) | UniProt   NCBI |
SRP72 | Signal recognition particle subunit SRP72 (SRP72) (Signal recognition particle 72 kDa protein) | UniProt   NCBI |
SRP14 | Signal recognition particle 14 kDa protein (SRP14) (18 kDa Alu RNA-binding protein) | UniProt   NCBI |
SRP9 | Signal recognition particle 9 kDa protein (SRP9) | UniProt   NCBI |
SRP54 | Signal recognition particle 54 kDa protein (SRP54) | UniProt   NCBI |
SRP19 | Signal recognition particle 19 kDa protein (SRP19) | UniProt   NCBI |
DNAJC9 | DnaJ homolog subfamily C member 9 (HDJC9) (DnaJ protein SB73) | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  GO:0005786 | 2.31084003444e-17 | 0.857142857143 | SRP68 SRP72 SRP14 SRP19 SRP9 SRP54 | signal recognition particle, endoplasmic reticulum targeting |
  GO:0048500 | 6.46960706472e-16 | 0.857142857143 | SRP68 SRP72 SRP14 SRP19 SRP9 SRP54 | signal recognition particle |
  KEGG:03060 | 2.44280981951e-15 | 0.857142857143 | SRP68 SRP72 SRP14 SRP19 SRP9 SRP54 | Protein export |
  GO:0008312 | 1.03206737618e-12 | 0.714285714286 | SRP68 SRP19 SRP14 SRP54 SRP72 | 7S RNA binding |
  REAC:R-HSA-1799339 | 1.73935576651e-10 | 0.857142857143 | SRP68 SRP72 SRP14 SRP19 SRP9 SRP54 | SRP-dependent cotranslational protein targeting to membrane |
  GO:0006614 | 1.43180479835e-08 | 0.857142857143 | SRP68 SRP72 SRP14 SRP19 SRP9 SRP54 | SRP-dependent cotranslational protein targeting to membrane |
  GO:0006613 | 2.13116011423e-08 | 0.857142857143 | SRP68 SRP72 SRP14 SRP19 SRP9 SRP54 | cotranslational protein targeting to membrane |
  GO:0045047 | 3.48664239809e-08 | 0.857142857143 | SRP68 SRP72 SRP14 SRP19 SRP9 SRP54 | protein targeting to ER |
  GO:0072599 | 4.39595027341e-08 | 0.857142857143 | SRP68 SRP72 SRP14 SRP19 SRP9 SRP54 | establishment of protein localization to endoplasmic reticulum |
  REAC:R-HSA-72766 | 5.96194030087e-08 | 0.857142857143 | SRP68 SRP72 SRP14 SRP19 SRP9 SRP54 | Translation |
  GO:0070972 | 1.43380219169e-07 | 0.857142857143 | SRP68 SRP72 SRP14 SRP19 SRP9 SRP54 | protein localization to endoplasmic reticulum |
  GO:0006612 | 5.64102731202e-07 | 0.857142857143 | SRP68 SRP72 SRP14 SRP19 SRP9 SRP54 | protein targeting to membrane |
  GO:0043021 | 7.92335684701e-06 | 0.714285714286 | SRP68 SRP19 SRP9 SRP54 SRP72 | ribonucleoprotein complex binding |
  GO:0090150 | 1.1322463778e-05 | 0.857142857143 | SRP68 SRP72 SRP14 SRP19 SRP9 SRP54 | establishment of protein localization to membrane |
  GO:0005047 | 1.27120391093e-05 | 0.428571428571 | SRP68 SRP9 SRP72 | signal recognition particle binding |
  GO:0006605 | 6.56328466887e-05 | 0.857142857143 | SRP68 SRP72 SRP14 SRP19 SRP9 SRP54 | protein targeting |
  GO:0072594 | 0.000334520650493 | 0.857142857143 | SRP68 SRP72 SRP14 SRP19 SRP9 SRP54 | establishment of protein localization to organelle |
  GO:0072657 | 0.000445099387973 | 0.857142857143 | SRP68 SRP72 SRP14 SRP19 SRP9 SRP54 | protein localization to membrane |
  REAC:R-HSA-392499 | 0.00334345902737 | 0.857142857143 | SRP68 SRP72 SRP14 SRP19 SRP9 SRP54 | Metabolism of proteins |
  GO:1990904 | 0.00548837347327 | 0.857142857143 | SRP68 SRP72 SRP14 SRP19 SRP9 SRP54 | ribonucleoprotein complex |
  GO:0033365 | 0.00607930828463 | 0.857142857143 | SRP68 SRP72 SRP14 SRP19 SRP9 SRP54 | protein localization to organelle |
  GO:0006617 | 0.00946729163895 | 0.285714285714 | SRP19 SRP54 | SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition |
  GO:0006886 | 0.0180209467821 | 0.857142857143 | SRP68 SRP72 SRP14 SRP19 SRP9 SRP54 | intracellular protein transport |
  GO:0042493 | 0.0189496806789 | 0.714285714286 | SRP68 SRP19 SRP14 SRP54 SRP72 | response to drug |
  HP:0001915 | 0.0218481766952 | 0.285714285714 | SRP72 SRP54 | Aplastic anemia |
  GO:0043022 | 0.0288395886243 | 0.428571428571 | SRP68 SRP19 SRP72 | ribosome binding |
Edges
Protein 1 | Protein 2 | Score | Precision | Evidence |
---|---|---|---|---|
 SRP72 |  SRP68 | 1.0 | 0.949           | hein_WMM     bioplex (SRP68)     bioplex_WMM     Guru     boldt     youn_WMM     hein (SRP72)     Malo     gupta_WMM     fraction     boldt_WMM     treiber_WMM     |
 SRP54 |  SRP19 | 0.998 | 0.941           | hein_WMM     bioplex_WMM     youn_WMM     Malo     gupta_WMM     fraction     |
 SRP72 |  SRP14 | 0.997 | 0.933           | hein_WMM     bioplex_WMM     boldt     youn_WMM     Malo     gupta_WMM     fraction     boldt_WMM     |
 SRP14 |  SRP9 | 0.981 | 0.897           | bioplex (SRP9)     bioplex_WMM     boldt     youn_WMM     gupta_WMM     fraction     boldt_WMM     treiber_WMM     |
 SRP68 |  SRP14 | 0.914 | 0.839           | bioplex (SRP68)     bioplex_WMM     boldt     youn_WMM     Malo     gupta_WMM     fraction     boldt_WMM     |
 SRP68 |  SRP54 | 0.878 | 0.812           | hein_WMM     bioplex (SRP68)     bioplex_WMM     youn_WMM     gupta_WMM     treiber_WMM     |
 SRP68 |  SRP19 | 0.422 | 0.573           | hein_WMM     bioplex (SRP68)     bioplex_WMM     youn_WMM     gupta_WMM     |
 SRP72 |  DNAJC9 | 0.241 | 0.468           | hein_WMM     bioplex_WMM     hein (SRP72)     gupta_WMM     fraction     |
 SRP9 |  SRP54 | 0.223 | 0.467           | bioplex (SRP9)     bioplex_WMM     youn_WMM     gupta_WMM     fraction     |
 SRP72 |  SRP19 | 0.114 | 0.385           | hein_WMM     bioplex_WMM     youn_WMM     hein (SRP72)     gupta_WMM     |
 SRP72 |  SRP9 | 0.098 | 0.358           | bioplex (SRP9)     bioplex_WMM     youn_WMM     gupta_WMM     |
 SRP9 |  SRP19 | 0.06 | 0.333           | bioplex (SRP9)     bioplex_WMM     youn_WMM     gupta_WMM     |
 SRP68 |  DNAJC9 | 0.03 | 0.23           | hein_WMM     bioplex (SRP68)     bioplex_WMM     boldt     youn_WMM     gupta_WMM     boldt_WMM     |
 SRP14 |  SRP19 | 0.009 | 0.109           | bioplex_WMM     youn_WMM     gupta_WMM     WMM_only     treiber_WMM     |
 SRP14 |  SRP54 | 0.009 | 0.102           | bioplex_WMM     youn_WMM     gupta_WMM     WMM_only     |
 SRP54 |  DNAJC9 | 0.008 | 0.096           | hein_WMM     bioplex_WMM     youn_WMM     gupta_WMM     WMM_only     treiber_WMM     |
 SRP14 |  DNAJC9 | 0.007 | 0.003           | bioplex_WMM     youn_WMM     gupta_WMM     WMM_only     treiber_WMM     |
 SRP9 |  DNAJC9 | 0.006 | 0.003           | bioplex (SRP9)     bioplex_WMM     gupta_WMM     treiber_WMM     |
 SRP72 |  SRP54 | 0.005 | 0.011           | hein_WMM     bioplex_WMM     youn_WMM     hein (SRP72)     gupta_WMM     treiber_WMM     |
 SRP68 |  SRP9 | 0.0 | 0.014           | bioplex (SRP68,SRP9)     bioplex_WMM     youn_WMM     gupta_WMM     fraction     |
 SRP19 |  DNAJC9 | 0.0 | 0.01           | hein_WMM     bioplex_WMM     gupta_WMM     fraction     treiber_WMM     |
Images
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Complex HuMAP2_00235 has an average edge precision of 0.406 which is ranked 3248 out of all 6965 complexes.
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