hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00248
Confidence: Medium High  
ProteinsGenename | Protein Name | Links |
---|---|---|
RAP1B | Ras-related protein Rap-1b (GTP-binding protein smg p21B) | UniProt   NCBI |
FAM71F2 | Protein FAM71F2 (Protein FAM137B) | UniProt   NCBI |
RAB7A | Ras-related protein Rab-7a | UniProt   NCBI |
RAB2A | Ras-related protein Rab-2A | UniProt   NCBI |
RAB2B | Ras-related protein Rab-2B | UniProt   NCBI |
RAB14 | Ras-related protein Rab-14 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  REAC:R-HSA-8873719 | 6.65127602182e-07 | 0.666666666667 | RAB14 RAB2B RAB2A RAB7A | RAB geranylgeranylation |
  GO:0019003 | 0.000216594058417 | 0.666666666667 | RAB14 RAB7A RAB2A RAP1B | GDP binding |
  GO:0003924 | 0.000349438575339 | 0.833333333333 | RAB2A RAB14 RAB2B RAB7A RAP1B | GTPase activity |
  GO:0032482 | 0.000352998651013 | 0.666666666667 | RAB14 RAB2B RAB2A RAB7A | Rab protein signal transduction |
  GO:0007265 | 0.000884985147402 | 0.833333333333 | RAB2A RAB14 RAB2B RAB7A RAP1B | Ras protein signal transduction |
  GO:0007264 | 0.00390084589509 | 0.833333333333 | RAB2A RAB14 RAB2B RAB7A RAP1B | small GTPase mediated signal transduction |
  GO:0005525 | 0.0123596040412 | 0.666666666667 | RAB14 RAB7A RAB2A RAP1B | GTP binding |
  GO:0032550 | 0.0165870922979 | 0.666666666667 | RAB14 RAB7A RAB2A RAP1B | purine ribonucleoside binding |
  GO:0032549 | 0.0165870922979 | 0.666666666667 | RAB14 RAB7A RAB2A RAP1B | ribonucleoside binding |
  GO:0001883 | 0.0169518190899 | 0.666666666667 | RAB14 RAB7A RAB2A RAP1B | purine nucleoside binding |
  GO:0001882 | 0.0180820254396 | 0.666666666667 | RAB14 RAB7A RAB2A RAP1B | nucleoside binding |
  GO:0032561 | 0.0209376514335 | 0.666666666667 | RAB14 RAB7A RAB2A RAP1B | guanyl ribonucleotide binding |
  GO:0019001 | 0.0213715329849 | 0.666666666667 | RAB14 RAB7A RAB2A RAP1B | guanyl nucleotide binding |
  GO:0017111 | 0.0247060250122 | 0.833333333333 | RAB2A RAB14 RAB2B RAB7A RAP1B | nucleoside-triphosphatase activity |
  GO:0016462 | 0.0345207756284 | 0.833333333333 | RAB2A RAB14 RAB2B RAB7A RAP1B | pyrophosphatase activity |
  GO:0016818 | 0.0350826142785 | 0.833333333333 | RAB2A RAB14 RAB2B RAB7A RAP1B | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
  GO:0016817 | 0.0350826142785 | 0.833333333333 | RAB2A RAB14 RAB2B RAB7A RAP1B | hydrolase activity, acting on acid anhydrides |
  KEGG:04152 | 0.0381607333212 | 0.333333333333 | RAB14 RAB2A | AMPK signaling pathway |
Edges
Protein 1 | Protein 2 | Score | Precision | Evidence |
---|---|---|---|---|
 RAB2B |  RAB2A | 0.618 | 0.674           | bioplex (RAB2B)     bioplex_WMM     youn_WMM     gupta_WMM     |
 RAB7A |  RAB2A | 0.135 | 0.407           | hein_WMM     bioplex_WMM     Guru     boldt     hein (RAB2A)     gupta_WMM     fraction     boldt_WMM     treiber_WMM     |
 RAP1B |  RAB7A | 0.11 | 0.379           | hein_WMM     bioplex_WMM     Guru     boldt     gupta_WMM     fraction     boldt_WMM     |
 RAB14 |  RAB7A | 0.065 | 0.347           | hein_WMM     bioplex_WMM     boldt     gupta_WMM     boldt_WMM     treiber_WMM     |
 RAB2B |  FAM71F2 | 0.058 | 0.323           | bioplex (FAM71F2)     bioplex_WMM     |
 RAB2B |  RAB14 | 0.046 | 0.293           | bioplex (RAB2B)     bioplex_WMM     youn_WMM     gupta_WMM     |
 RAB14 |  RAB2A | 0.013 | 0.149           | bioplex_WMM     boldt     youn_WMM     gupta_WMM     boldt_WMM     treiber_WMM     |
 FAM71F2 |  RAB2A | 0.012 | 0.147           | bioplex (FAM71F2)     bioplex_WMM     |
 RAB14 |  RAP1B | 0.01 | 0.103           | hein_WMM     bioplex_WMM     boldt     gupta_WMM     boldt_WMM     |
 RAB2B |  RAB7A | 0.009 | 0.097           | bioplex (RAB2B)     bioplex_WMM     gupta_WMM     |
 RAB2B |  RAP1B | 0.007 | 0.002           | bioplex (RAB2B)     bioplex_WMM     |
 RAP1B |  RAB2A | 0.006 | 0.009           | bioplex_WMM     Guru     boldt     gupta_WMM     fraction     boldt_WMM     |
Images
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Complex HuMAP2_00248 has an average edge precision of 0.244 which is ranked 5468 out of all 6965 complexes.
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