hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00280
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ERO1A | ERO1-like protein alpha (ERO1-L) (ERO1-L-alpha) (EC 1.8.4.-) (Endoplasmic oxidoreductin-1-like protein) (Endoplasmic reticulum oxidoreductase alpha) (Oxidoreductin-1-L-alpha) | UniProt NCBI |
| ERO1B | ERO1-like protein beta (ERO1-L-beta) (EC 1.8.4.-) (Endoplasmic reticulum oxidoreductase beta) (Endoplasmic reticulum oxidoreductin-1-like protein B) (Oxidoreductin-1-L-beta) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-264876 | 0.000462554875615 | 1.0 | ERO1A ERO1B | Insulin processing |
| KEGG:04141 | 0.00178666132548 | 1.0 | ERO1A ERO1B | Protein processing in endoplasmic reticulum |
| REAC:R-HSA-2980736 | 0.00393171644273 | 1.0 | ERO1A ERO1B | Peptide hormone metabolism |
| GO:0015035 | 0.020287053512 | 1.0 | ERO1A ERO1B | protein disulfide oxidoreductase activity |
| GO:0034975 | 0.020287053512 | 1.0 | ERO1A ERO1B | protein folding in endoplasmic reticulum |
| GO:0003756 | 0.0410249304355 | 1.0 | ERO1A ERO1B | protein disulfide isomerase activity |
| GO:0016864 | 0.0410249304355 | 1.0 | ERO1A ERO1B | intramolecular oxidoreductase activity, transposing S-S bonds |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ERO1B | ERO1A | 0.769 | 0.749 | bioplex (ERO1B) bioplex_WMM gupta_WMM |
Images
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Complex HuMAP2_00280 has an average edge precision of 0.749 which is ranked 1157 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ERO1A | HuMAP2_00280 HuMAP2_00382 HuMAP2_02165 HuMAP2_02991 HuMAP2_06451 |
| ERO1B | HuMAP2_00147 HuMAP2_00280 HuMAP2_04379 HuMAP2_05789 |