hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00287
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DHRS7 | Dehydrogenase/reductase SDR family member 7 (EC 1.1.-.-) (Retinal short-chain dehydrogenase/reductase 4) (retSDR4) (Short chain dehydrogenase/reductase family 34C member 1) | UniProt NCBI |
| ESYT1 | Extended synaptotagmin-1 (E-Syt1) (Membrane-bound C2 domain-containing protein) | UniProt NCBI |
| TEX264 | Testis-expressed protein 264 (Putative secreted protein Zsig11) | UniProt NCBI |
| TBL2 | Transducin beta-like protein 2 (WS beta-transducin repeats protein) (WS-betaTRP) (Williams-Beuren syndrome chromosomal region 13 protein) | UniProt NCBI |
| CYP51A1 | Lanosterol 14-alpha demethylase (LDM) (EC 1.14.14.154) (CYPLI) (Cytochrome P450 51A1) (Cytochrome P450-14DM) (Cytochrome P45014DM) (Cytochrome P450LI) (Sterol 14-alpha demethylase) | UniProt NCBI |
| ANO6 | Anoctamin-6 (Small-conductance calcium-activated nonselective cation channel) (SCAN channel) (Transmembrane protein 16F) | UniProt NCBI |
| PREB | Prolactin regulatory element-binding protein (Mammalian guanine nucleotide exchange factor mSec12) | UniProt NCBI |
| PDE3B | cGMP-inhibited 3',5'-cyclic phosphodiesterase B (EC 3.1.4.17) (CGIPDE1) (CGIP1) (Cyclic GMP-inhibited phosphodiesterase B) (CGI-PDE B) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7313 | 0.0497224828424 | 0.125 | ESYT1 | ESYT1-ESYT2 complex |
| CORUM:7314 | 0.0497224828424 | 0.125 | ESYT1 | ESYT1-ESYT3 complex |
| CORUM:7477 | 0.0497224828424 | 0.125 | PREB | TANGO1L-cTAGE5-SEC12 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TEX264 | PREB | 0.555 | 0.647 | bioplex (TEX264) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| TEX264 | ESYT1 | 0.148 | 0.409 | bioplex (TEX264) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| TEX264 | PDE3B | 0.035 | 0.266 | bioplex (TEX264) bioplex_WMM youn_WMM |
| DHRS7 | TEX264 | 0.033 | 0.252 | bioplex_WMM youn_WMM gupta_WMM WMM_only boldt_WMM |
| TEX264 | TBL2 | 0.031 | 0.238 | bioplex (TEX264) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| DHRS7 | CYP51A1 | 0.027 | 0.229 | bioplex_WMM youn_WMM gupta_WMM WMM_only boldt_WMM |
| ANO6 | PREB | 0.021 | 0.191 | bioplex (ANO6) bioplex_WMM youn_WMM gupta_WMM |
| CYP51A1 | ESYT1 | 0.021 | 0.187 | bioplex (CYP51A1) bioplex_WMM youn_WMM gupta_WMM boldt_WMM |
| DHRS7 | PREB | 0.018 | 0.178 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| DHRS7 | ESYT1 | 0.011 | 0.142 | bioplex_WMM youn_WMM gupta_WMM WMM_only boldt_WMM |
| DHRS7 | TBL2 | 0.009 | 0.09 | bioplex_WMM youn_WMM gupta_WMM WMM_only boldt_WMM |
| TEX264 | ANO6 | 0.009 | 0.097 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| DHRS7 | ANO6 | 0.008 | 0.094 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| TBL2 | PREB | 0.007 | 0.008 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| TBL2 | ANO6 | 0.007 | 0.007 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| ESYT1 | ANO6 | 0.007 | 0.004 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| CYP51A1 | ANO6 | 0.007 | 0.001 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| PDE3B | ANO6 | 0.007 | 0.003 | bioplex_WMM youn_WMM WMM_only |
| TBL2 | ESYT1 | 0.007 | 0.004 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| DHRS7 | PDE3B | 0.006 | 0.008 | bioplex_WMM youn_WMM WMM_only |
| TBL2 | CYP51A1 | 0.006 | 0.008 | bioplex_WMM youn_WMM gupta_WMM WMM_only boldt_WMM |
| TBL2 | PDE3B | 0.004 | 0.011 | bioplex_WMM youn_WMM WMM_only |
| PDE3B | CYP51A1 | 0.004 | 0.011 | bioplex_WMM youn_WMM WMM_only |
| PDE3B | ESYT1 | 0.004 | 0.008 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| ESYT1 | PREB | 0.003 | 0.018 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| CYP51A1 | PREB | 0.003 | 0.012 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| PDE3B | PREB | 0.003 | 0.009 | bioplex_WMM youn_WMM WMM_only |
| TEX264 | CYP51A1 | 0.0 | 0.011 | bioplex (TEX264) bioplex_WMM youn_WMM gupta_WMM boldt_WMM |
Images
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Complex HuMAP2_00287 has an average edge precision of 0.112 which is ranked 6900 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DHRS7 | HuMAP2_00287 HuMAP2_01487 HuMAP2_01699 HuMAP2_06362 |
| ESYT1 | HuMAP2_00287 HuMAP2_00907 HuMAP2_01322 HuMAP2_06362 |
| TEX264 | HuMAP2_00287 HuMAP2_00907 HuMAP2_04372 HuMAP2_06362 |
| TBL2 | HuMAP2_00287 HuMAP2_01734 HuMAP2_02727 |
| CYP51A1 | HuMAP2_00287 HuMAP2_04140 HuMAP2_06362 |
| ANO6 | HuMAP2_00287 HuMAP2_03233 |
| PREB | HuMAP2_00287 HuMAP2_00907 HuMAP2_03233 HuMAP2_04372 HuMAP2_06362 |
| PDE3B | HuMAP2_00287 HuMAP2_06362 |