hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00298
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| REEP6 | Receptor expression-enhancing protein 6 (Polyposis locus protein 1-like 1) | UniProt NCBI |
| IL2RG | Cytokine receptor common subunit gamma (Interleukin-2 receptor subunit gamma) (IL-2 receptor subunit gamma) (IL-2R subunit gamma) (IL-2RG) (gammaC) (p64) (CD antigen CD132) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0005428 | 0.0497341708567 | 0.5 | IL2RG | Severe recurrent varicella |
| HP:0007274 | 0.0497341708567 | 0.5 | IL2RG | Recurrent bacterial meningitis |
| HP:0031396 | 0.0497341708567 | 0.5 | IL2RG | Abnormal proportion of naive T cells |
| HP:0031397 | 0.0497341708567 | 0.5 | IL2RG | Reduced proportion of naive T cells |
| HP:0031545 | 0.0497341708567 | 0.5 | IL2RG | Abnormally low T cell receptor excision circle level |
| CORUM:1515 | 0.0499173803268 | 0.5 | IL2RG | IL4-IL4R-IL2RG complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| REEP6 | IL2RG | 0.079 | 0.352 | bioplex (IL2RG) bioplex_WMM |
Images
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Complex HuMAP2_00298 has an average edge precision of 0.352 which is ranked 3909 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| REEP6 | HuMAP2_00298 HuMAP2_00889 HuMAP2_04316 |
| IL2RG | HuMAP2_00298 HuMAP2_04316 |