hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_00301
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SMC1A | Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1-alpha) (SMC-1A) (Sb1.8) | UniProt NCBI |
| SMC3 | Structural maintenance of chromosomes protein 3 (SMC protein 3) (SMC-3) (Basement membrane-associated chondroitin proteoglycan) (Bamacan) (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) | UniProt NCBI |
| RAD21 | Double-strand-break repair protein rad21 homolog (hHR21) (Nuclear matrix protein 1) (NXP-1) (SCC1 homolog) [Cleaved into: 64-kDa C-terminal product (64-kDa carboxy-terminal product) (65-kDa carboxy-terminal product)] | UniProt NCBI |
| PDS5B | Sister chromatid cohesion protein PDS5 homolog B (Androgen-induced proliferation inhibitor) (Androgen-induced prostate proliferative shutoff-associated protein AS3) | UniProt NCBI |
| PDS5A | Sister chromatid cohesion protein PDS5 homolog A (Cell proliferation-inducing gene 54 protein) (Sister chromatid cohesion protein 112) (SCC-112) | UniProt NCBI |
| STAG1 | Cohesin subunit SA-1 (SCC3 homolog 1) (Stromal antigen 1) | UniProt NCBI |
| BANF1 | Barrier-to-autointegration factor (Breakpoint cluster region protein 1) [Cleaved into: Barrier-to-autointegration factor, N-terminally processed] | UniProt NCBI |
| STAG2 | Cohesin subunit SA-2 (SCC3 homolog 2) (Stromal antigen 2) | UniProt NCBI |
| SMC1B | Structural maintenance of chromosomes protein 1B (SMC protein 1B) (SMC-1-beta) (SMC-1B) | UniProt NCBI |
| CDCA5 | Sororin (Cell division cycle-associated protein 5) (p35) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-2468052 | 2.59035484958e-23 | 0.8 | STAG1 PDS5A PDS5B SMC1A RAD21 STAG2 CDCA5 SMC3 | Establishment of Sister Chromatid Cohesion |
| REAC:R-HSA-2470946 | 9.34691612057e-20 | 0.7 | STAG1 PDS5A PDS5B SMC1A RAD21 STAG2 SMC3 | Cohesin Loading onto Chromatin |
| CORUM:5432 | 1.03162501538e-18 | 0.6 | RAD21 PDS5A PDS5B SMC1A CDCA5 SMC3 | Sororin-cohesin complex |
| CORUM:1856 | 1.03162501538e-18 | 0.6 | RAD21 PDS5A PDS5B SMC1A CDCA5 SMC3 | Sororin-cohesin complex |
| REAC:R-HSA-68884 | 2.67133257002e-18 | 0.7 | STAG1 PDS5A PDS5B SMC1A RAD21 STAG2 SMC3 | Mitotic Telophase/Cytokinesis |
| GO:0008278 | 1.47386254028e-16 | 0.7 | SMC1B STAG1 STAG2 SMC1A RAD21 CDCA5 SMC3 | cohesin complex |
| GO:0007062 | 1.40959669731e-14 | 0.8 | STAG1 PDS5A PDS5B SMC1A RAD21 STAG2 CDCA5 SMC3 | sister chromatid cohesion |
| REAC:R-HSA-68882 | 1.60663073179e-14 | 0.9 | STAG1 BANF1 PDS5A PDS5B SMC1A RAD21 STAG2 CDCA5 SMC3 | Mitotic Anaphase |
| REAC:R-HSA-2555396 | 1.68554230379e-14 | 0.9 | STAG1 BANF1 PDS5A PDS5B SMC1A RAD21 STAG2 CDCA5 SMC3 | Mitotic Metaphase and Anaphase |
| REAC:R-HSA-2500257 | 1.30201852572e-13 | 0.8 | STAG1 PDS5A PDS5B SMC1A RAD21 STAG2 CDCA5 SMC3 | Resolution of Sister Chromatid Cohesion |
| REAC:R-HSA-69242 | 1.30649940142e-12 | 0.8 | STAG1 PDS5A PDS5B SMC1A RAD21 STAG2 CDCA5 SMC3 | S Phase |
| REAC:R-HSA-1640170 | 2.95031995123e-12 | 1.0 | SMC1B STAG1 BANF1 PDS5A PDS5B SMC1A RAD21 STAG2 CDCA5 SMC3 | Cell Cycle |
| REAC:R-HSA-2467813 | 4.10789123391e-12 | 0.8 | STAG1 PDS5A PDS5B SMC1A RAD21 STAG2 CDCA5 SMC3 | Separation of Sister Chromatids |
| REAC:R-HSA-68877 | 5.81725052283e-12 | 0.8 | STAG1 PDS5A PDS5B SMC1A RAD21 STAG2 CDCA5 SMC3 | Mitotic Prometaphase |
| CORUM:64 | 7.6236129225e-12 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Cohesin-SA2 complex |
| CORUM:163 | 7.6236129225e-12 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Cohesin-SA2 complex |
| CORUM:164 | 7.6236129225e-12 | 0.4 | STAG1 SMC1A SMC3 RAD21 | Cohesin-SA1 complex |
| CORUM:165 | 7.6236129225e-12 | 0.4 | STAG1 SMC1A SMC3 RAD21 | Cohesin-SA1 complex |
| CORUM:166 | 7.6236129225e-12 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Cohesin-SA2 complex |
| CORUM:63 | 7.6236129225e-12 | 0.4 | STAG1 SMC1A SMC3 RAD21 | Cohesin-SA1 complex |
| REAC:R-HSA-68886 | 7.94389111018e-12 | 0.9 | STAG1 BANF1 PDS5A PDS5B SMC1A RAD21 STAG2 CDCA5 SMC3 | M Phase |
| CORUM:282 | 1.33771192079e-11 | 0.5 | STAG1 SMC1A SMC3 RAD21 STAG2 | SNF2h-cohesin-NuRD complex |
| GO:0007059 | 4.85671678292e-11 | 0.9 | STAG1 BANF1 PDS5A PDS5B SMC1A RAD21 STAG2 CDCA5 SMC3 | chromosome segregation |
| GO:0000775 | 9.23698132849e-11 | 0.8 | STAG1 PDS5A PDS5B SMC1A RAD21 STAG2 CDCA5 SMC3 | chromosome, centromeric region |
| REAC:R-HSA-69278 | 1.36263077643e-10 | 0.9 | STAG1 BANF1 PDS5A PDS5B SMC1A RAD21 STAG2 CDCA5 SMC3 | Cell Cycle, Mitotic |
| GO:0000819 | 4.22432807565e-10 | 0.8 | STAG1 PDS5A PDS5B SMC1A RAD21 STAG2 CDCA5 SMC3 | sister chromatid segregation |
| REAC:R-HSA-1221632 | 5.74845329488e-10 | 0.6 | RAD21 STAG1 SMC1A SMC1B STAG2 SMC3 | Meiotic synapsis |
| KEGG:04110 | 2.37158875908e-09 | 0.6 | RAD21 STAG1 SMC1A SMC1B STAG2 SMC3 | Cell cycle |
| WP:WP179 | 2.50363462937e-09 | 0.6 | RAD21 STAG1 SMC1A SMC1B STAG2 SMC3 | Cell Cycle |
| GO:0098813 | 2.67190285596e-09 | 0.8 | STAG1 PDS5A PDS5B SMC1A RAD21 STAG2 CDCA5 SMC3 | nuclear chromosome segregation |
| WP:WP4240 | 6.38162336549e-09 | 0.4 | STAG1 SMC1A SMC3 RAD21 | Regulation of sister chromatid separation at the metaphase-anaphase transition |
| GO:0000793 | 7.05972874285e-09 | 0.7 | SMC1B STAG1 STAG2 SMC1A RAD21 CDCA5 SMC3 | condensed chromosome |
| REAC:R-HSA-1500620 | 7.54518943043e-09 | 0.6 | RAD21 STAG1 SMC1A SMC1B STAG2 SMC3 | Meiosis |
| REAC:R-HSA-1474165 | 1.45810632909e-08 | 0.6 | RAD21 STAG1 SMC1A SMC1B STAG2 SMC3 | Reproduction |
| GO:0098687 | 2.5084153078e-08 | 0.8 | STAG1 PDS5A PDS5B SMC1A RAD21 STAG2 CDCA5 SMC3 | chromosomal region |
| CORUM:6303 | 6.48475406063e-08 | 0.3 | RAD21 SMC3 SMC1A | DDX11-RAD21-SMC1A-SMC3 complex |
| GO:0000280 | 6.63450852196e-08 | 0.8 | STAG1 PDS5A PDS5B SMC1A RAD21 STAG2 CDCA5 SMC3 | nuclear division |
| REAC:R-HSA-3108214 | 1.10398002625e-07 | 0.5 | STAG1 SMC1A SMC3 RAD21 STAG2 | SUMOylation of DNA damage response and repair proteins |
| GO:0048285 | 1.65310476174e-07 | 0.8 | STAG1 PDS5A PDS5B SMC1A RAD21 STAG2 CDCA5 SMC3 | organelle fission |
| GO:0030893 | 1.79134017731e-07 | 0.4 | RAD21 SMC1B SMC3 SMC1A | meiotic cohesin complex |
| GO:0140014 | 1.00541320683e-06 | 0.7 | STAG1 PDS5A PDS5B SMC1A CDCA5 STAG2 SMC3 | mitotic nuclear division |
| REAC:R-HSA-9018519 | 3.59403491999e-06 | 0.5 | STAG1 SMC1A SMC3 RAD21 STAG2 | Estrogen-dependent gene expression |
| GO:0051276 | 6.44350061995e-06 | 0.9 | STAG1 BANF1 PDS5A PDS5B SMC1A RAD21 STAG2 CDCA5 SMC3 | chromosome organization |
| REAC:R-HSA-3108232 | 8.16014580173e-06 | 0.5 | STAG1 SMC1A SMC3 RAD21 STAG2 | SUMO E3 ligases SUMOylate target proteins |
| GO:0016363 | 9.31970314181e-06 | 0.5 | STAG1 SMC1A SMC3 RAD21 STAG2 | nuclear matrix |
| REAC:R-HSA-2990846 | 9.74975296949e-06 | 0.5 | STAG1 SMC1A SMC3 RAD21 STAG2 | SUMOylation |
| GO:1901673 | 1.56059663557e-05 | 0.4 | STAG1 SMC1A SMC3 STAG2 | regulation of mitotic spindle assembly |
| HP:0000667 | 1.89067113309e-05 | 0.3 | RAD21 SMC3 SMC1A | Phthisis bulbi |
| REAC:R-HSA-8939211 | 2.28877240149e-05 | 0.5 | STAG1 SMC1A SMC3 RAD21 STAG2 | ESR-mediated signaling |
| HP:0002580 | 2.59875606851e-05 | 0.3 | RAD21 SMC3 SMC1A | Volvulus |
| GO:0034399 | 2.8346200728e-05 | 0.5 | STAG1 SMC1A SMC3 RAD21 STAG2 | nuclear periphery |
| GO:0022402 | 2.84336717155e-05 | 0.9 | STAG1 BANF1 PDS5A PDS5B SMC1A RAD21 STAG2 CDCA5 SMC3 | cell cycle process |
| CORUM:5241 | 3.01890677263e-05 | 0.2 | SMC3 SMC1A | SMC1-SMC3 complex |
| GO:0007064 | 3.0493905917e-05 | 0.4 | PDS5B CDCA5 PDS5A SMC1A | mitotic sister chromatid cohesion |
| HP:0000294 | 3.09566207954e-05 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Low anterior hairline |
| HP:0010300 | 3.46378616618e-05 | 0.3 | RAD21 SMC3 SMC1A | Abnormally low-pitched voice |
| HP:0000534 | 4.2547232005e-05 | 0.6 | STAG1 BANF1 SMC1A RAD21 STAG2 SMC3 | Abnormal eyebrow morphology |
| HP:0007665 | 4.50133402557e-05 | 0.3 | RAD21 SMC3 SMC1A | Curly eyelashes |
| GO:0090169 | 5.40876759136e-05 | 0.4 | STAG1 SMC1A SMC3 STAG2 | regulation of spindle assembly |
| GO:1903047 | 5.54626397565e-05 | 0.8 | STAG1 PDS5A BANF1 PDS5B SMC1A CDCA5 STAG2 SMC3 | mitotic cell cycle process |
| REAC:R-HSA-9006931 | 5.58500358001e-05 | 0.5 | STAG1 SMC1A SMC3 RAD21 STAG2 | Signaling by Nuclear Receptors |
| HP:0000776 | 5.92293908645e-05 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Congenital diaphragmatic hernia |
| GO:0097431 | 6.43693156641e-05 | 0.4 | STAG1 SMC1A SMC3 STAG2 | mitotic spindle pole |
| GO:0044427 | 7.653029207e-05 | 0.9 | SMC1B STAG1 PDS5A PDS5B SMC1A RAD21 STAG2 CDCA5 SMC3 | chromosomal part |
| HP:0010034 | 8.80447884859e-05 | 0.3 | RAD21 SMC3 SMC1A | Short 1st metacarpal |
| GO:0005694 | 0.000105741912425 | 0.9 | SMC1B STAG1 PDS5A PDS5B SMC1A RAD21 STAG2 CDCA5 SMC3 | chromosome |
| HP:0000775 | 0.000120494500608 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Abnormality of the diaphragm |
| HP:0000692 | 0.000123603612772 | 0.5 | STAG1 SMC1A SMC3 RAD21 BANF1 | Misalignment of teeth |
| GO:0007049 | 0.000132147341073 | 0.9 | STAG1 BANF1 PDS5A PDS5B SMC1A RAD21 STAG2 CDCA5 SMC3 | cell cycle |
| HP:0000599 | 0.000176374940201 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Abnormality of the frontal hairline |
| GO:0000278 | 0.000186820011075 | 0.8 | STAG1 PDS5A BANF1 PDS5B SMC1A CDCA5 STAG2 SMC3 | mitotic cell cycle |
| HP:0000319 | 0.000201644612458 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Smooth philtrum |
| HP:0010026 | 0.000208737851018 | 0.3 | RAD21 SMC3 SMC1A | Aplasia/Hypoplasia of the 1st metacarpal |
| GO:0060236 | 0.000235299011022 | 0.4 | STAG1 SMC1A SMC3 STAG2 | regulation of mitotic spindle organization |
| HP:0010009 | 0.000241611199792 | 0.3 | RAD21 SMC3 SMC1A | Abnormality of the 1st metacarpal |
| HP:0009660 | 0.000241611199792 | 0.3 | RAD21 SMC3 SMC1A | Short phalanx of the thumb |
| HP:0008850 | 0.000277754863218 | 0.3 | RAD21 SMC3 SMC1A | Severe postnatal growth retardation |
| GO:0090224 | 0.000334769693204 | 0.4 | STAG1 SMC1A SMC3 STAG2 | regulation of spindle organization |
| HP:0012165 | 0.000360466136352 | 0.3 | RAD21 SMC3 SMC1A | Oligodactyly |
| HP:0002557 | 0.000360466136352 | 0.3 | RAD21 SMC3 SMC1A | Hypoplastic nipples |
| HP:0010880 | 0.000407339699917 | 0.3 | RAD21 SMC3 SMC1A | Increased nuchal translucency |
| HP:0002553 | 0.000495210583411 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Highly arched eyebrow |
| HP:0009658 | 0.000571863230327 | 0.3 | RAD21 SMC3 SMC1A | Aplasia/Hypoplasia of the phalanges of the thumb |
| GO:0007088 | 0.000616180535985 | 0.5 | CDCA5 STAG1 SMC1A SMC3 STAG2 | regulation of mitotic nuclear division |
| HP:0009623 | 0.000702986193736 | 0.3 | RAD21 SMC3 SMC1A | Proximal placement of thumb |
| HP:0000059 | 0.000702986193736 | 0.3 | RAD21 SMC3 SMC1A | Hypoplastic labia majora |
| GO:0051783 | 0.00082874774691 | 0.5 | CDCA5 STAG1 SMC1A SMC3 STAG2 | regulation of nuclear division |
| HP:0009603 | 0.000934864900096 | 0.3 | RAD21 SMC3 SMC1A | Deviation of the thumb |
| HP:0012881 | 0.00102214764966 | 0.3 | RAD21 SMC3 SMC1A | Abnormality of the labia majora |
| CORUM:0000000 | 0.00104233586959 | 0.9 | STAG1 BANF1 PDS5A PDS5B SMC1A RAD21 STAG2 CDCA5 SMC3 | CORUM root |
| HP:0001956 | 0.00111467665235 | 0.3 | RAD21 SMC3 SMC1A | Truncal obesity |
| HP:0009553 | 0.0011206552102 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Abnormality of the hairline |
| GO:0090307 | 0.00136562237441 | 0.4 | STAG1 SMC1A SMC3 STAG2 | mitotic spindle assembly |
| HP:0006709 | 0.00142524481807 | 0.3 | RAD21 SMC3 SMC1A | Aplasia/Hypoplasia of the nipples |
| HPA:014010_12 | 0.00147597688315 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | endometrium 2; cells in endometrial stroma[Supported,Medium] |
| HP:0000413 | 0.00154026138941 | 0.3 | RAD21 SMC3 SMC1A | Atresia of the external auditory canal |
| HP:0011361 | 0.00155290078924 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Congenital abnormal hair pattern |
| HP:0001387 | 0.00155290078924 | 0.4 | RAD21 SMC1A SMC3 BANF1 | Joint stiffness |
| HP:0000498 | 0.00178843326976 | 0.3 | RAD21 SMC3 SMC1A | Blepharitis |
| KEGG:04114 | 0.00200492773446 | 0.3 | SMC1B SMC3 SMC1A | Oocyte meiosis |
| HP:0000066 | 0.00206178499151 | 0.3 | RAD21 SMC3 SMC1A | Labial hypoplasia |
| HP:0010720 | 0.00230837146613 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Abnormal hair pattern |
| HP:0012815 | 0.00236150736559 | 0.3 | RAD21 SMC3 SMC1A | Hypoplastic female external genitalia |
| HPA:035020_13 | 0.00242705892958 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | placenta; trophoblastic cells[Supported,High] |
| HPA:006010_12 | 0.00247322655317 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | caudate; glial cells[Supported,Medium] |
| HP:0002973 | 0.00253361522712 | 0.4 | RAD21 SMC1A SMC3 BANF1 | Abnormality of the forearm |
| HPA:031020_12 | 0.00254377170622 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | ovary; ovarian stroma cells[Supported,Medium] |
| HP:0000219 | 0.00277479012861 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Thin upper lip vermilion |
| HP:0000499 | 0.00277479012861 | 0.4 | RAD21 SMC1A SMC3 BANF1 | Abnormal eyelash morphology |
| HPA:008020_12 | 0.00397154956368 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | cerebral cortex; glial cells[Supported,Medium] |
| HPA:004010_11 | 0.00400541864789 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | breast; adipocytes[Supported,Low] |
| HPA:032020_13 | 0.00410948066912 | 0.4 | STAG1 SMC1A RAD21 STAG2 | pancreas; islets of Langerhans[Supported,High] |
| HP:0001595 | 0.00444473881144 | 0.6 | STAG1 BANF1 SMC1A RAD21 STAG2 SMC3 | Abnormal hair morphology |
| HPA:007020_12 | 0.00446673919877 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | cerebellum; cells in granular layer[Supported,Medium] |
| HP:0007018 | 0.00459742021001 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Attention deficit hyperactivity disorder |
| HP:0000687 | 0.00477987740585 | 0.3 | RAD21 SMC3 SMC1A | Widely spaced teeth |
| HPA:024010_12 | 0.00488881395338 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | kidney; cells in glomeruli[Supported,Medium] |
| HP:0002974 | 0.00503416384107 | 0.3 | RAD21 SMC3 SMC1A | Radioulnar synostosis |
| HP:0007598 | 0.00503416384107 | 0.3 | RAD21 SMC3 SMC1A | Bilateral single transverse palmar creases |
| HP:0000372 | 0.00503416384107 | 0.3 | RAD21 SMC3 SMC1A | Abnormality of the auditory canal |
| HP:0000965 | 0.00529724841043 | 0.3 | RAD21 SMC3 SMC1A | Cutis marmorata |
| HPA:027020_12 | 0.00555797820701 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | lung; pneumocytes[Supported,Medium] |
| HP:0000058 | 0.00556927643388 | 0.3 | RAD21 SMC3 SMC1A | Abnormality of the labia |
| HP:0009778 | 0.00585039301888 | 0.3 | RAD21 SMC3 SMC1A | Short thumb |
| HPA:002020_02 | 0.00599209101903 | 0.6 | STAG1 PDS5B SMC1A RAD21 STAG2 SMC3 | appendix; lymphoid tissue[Uncertain,Medium] |
| HPA:041010_12 | 0.00601136385049 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | skeletal muscle; myocytes[Supported,Medium] |
| HPA:011010_12 | 0.00620063401085 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | colon; endothelial cells[Supported,Medium] |
| HPA:007030_12 | 0.00620063401085 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | cerebellum; cells in molecular layer[Supported,Medium] |
| HPA:048010_11 | 0.00644376153343 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | soft tissue 2; adipocytes[Supported,Low] |
| HPA:032020_12 | 0.0064932717269 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | pancreas; islets of Langerhans[Supported,Medium] |
| HPA:043010_12 | 0.00654307980398 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | skin 1; Langerhans[Supported,Medium] |
| HPA:004010_01 | 0.00657567179967 | 0.6 | STAG1 PDS5B SMC1A RAD21 STAG2 SMC3 | breast; adipocytes[Uncertain,Low] |
| HP:0100037 | 0.00669360807697 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Abnormality of the scalp hair |
| HPA:002020_12 | 0.00669430422156 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | appendix; lymphoid tissue[Supported,Medium] |
| HP:0001965 | 0.00731276958398 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Abnormality of the scalp |
| HP:0004209 | 0.0075719372093 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Clinodactyly of the 5th finger |
| HP:0009179 | 0.00783784431049 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Deviation of the 5th finger |
| HP:0000739 | 0.00783784431049 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Anxiety |
| HPA:009020_12 | 0.00794692993305 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | cervix, uterine; squamous epithelial cells[Supported,Medium] |
| HP:0000722 | 0.0080848333203 | 0.3 | RAD21 SMC3 SMC1A | Obsessive-compulsive behavior |
| HP:0003042 | 0.0080848333203 | 0.3 | RAD21 SMC3 SMC1A | Elbow dislocation |
| HPA:022020_12 | 0.00824203602841 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | hippocampus; neuronal cells[Supported,Medium] |
| HPA:014010_11 | 0.00824203602841 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | endometrium 2; cells in endometrial stroma[Supported,Low] |
| HP:0100852 | 0.0082495866387 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Abnormal fear/anxiety-related behavior |
| HP:0000233 | 0.00853283404517 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Thin vermilion border |
| HPA:004030_12 | 0.00866953324677 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | breast; myoepithelial cells[Supported,Medium] |
| HPA:033010_12 | 0.00873199507374 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | parathyroid gland; glandular cells[Supported,Medium] |
| HP:0030141 | 0.00881326532308 | 0.3 | RAD21 SMC3 SMC1A | Abnormality of the posterior hairline |
| HP:0002162 | 0.00881326532308 | 0.3 | RAD21 SMC3 SMC1A | Low posterior hairline |
| HP:0002020 | 0.0088232162911 | 0.4 | STAG1 SMC1A SMC3 RAD21 | Gastroesophageal reflux |
| HP:0011138 | 0.00911168875213 | 0.6 | STAG1 BANF1 SMC1A RAD21 STAG2 SMC3 | Abnormality of skin adnexa morphology |
| HPA:043040_12 | 0.00911420639738 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | skin 1; melanocytes[Supported,Medium] |
| HP:0000527 | 0.00919320180908 | 0.3 | RAD21 SMC3 SMC1A | Long eyelashes |
| WP:WP3995 | 0.00948491249007 | 0.2 | RAD21 SMC3 | Prion disease pathway |
| HP:0200055 | 0.00958380906364 | 0.3 | RAD21 SMC3 SMC1A | Small hand |
| HP:0000347 | 0.00965508242263 | 0.5 | STAG2 SMC1A SMC3 RAD21 BANF1 | Micrognathia |
| HPA:009010_12 | 0.00971195520636 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | cervix, uterine; glandular cells[Supported,Medium] |
| HPA:058010_13 | 0.00980734259497 | 0.4 | STAG1 SMC1A RAD21 PDS5B | vagina; squamous epithelial cells[Supported,High] |
| HP:0009118 | 0.00991873890199 | 0.5 | STAG2 SMC1A SMC3 RAD21 BANF1 | Aplasia/Hypoplasia of the mandible |
| GO:0005654 | 0.00998195755149 | 1.0 | SMC1B STAG1 BANF1 PDS5A PDS5B SMC1A RAD21 STAG2 CDCA5 SMC3 | nucleoplasm |
| HPA:022010_11 | 0.0101271999314 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | hippocampus; glial cells[Supported,Low] |
| HPA:048030_11 | 0.0102686585575 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | soft tissue 2; fibroblasts[Supported,Low] |
| HP:0009116 | 0.010743846845 | 0.5 | STAG2 SMC1A SMC3 RAD21 BANF1 | Aplasia/Hypoplasia involving bones of the skull |
| HP:0002566 | 0.010821080098 | 0.3 | RAD21 SMC3 SMC1A | Intestinal malrotation |
| HP:0040019 | 0.0108926099659 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Finger clinodactyly |
| HPA:047030_11 | 0.0110745615312 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | soft tissue 1; fibroblasts[Supported,Low] |
| HP:0030310 | 0.0112557940356 | 0.3 | RAD21 SMC3 SMC1A | Upper extremity joint dislocation |
| HPA:058010_12 | 0.0113795728511 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | vagina; squamous epithelial cells[Supported,Medium] |
| HPA:027010_12 | 0.0114568423932 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | lung; macrophages[Supported,Medium] |
| HPA:004020_13 | 0.0115536536592 | 0.4 | STAG1 SMC1A RAD21 PDS5B | breast; glandular cells[Supported,High] |
| HP:0011339 | 0.0115959529737 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Abnormality of upper lip vermillion |
| HPA:008010_11 | 0.0116126123506 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | cerebral cortex; endothelial cells[Supported,Low] |
| HPA:056020_12 | 0.0119291192956 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | tonsil; non-germinal center cells[Supported,Medium] |
| HP:0000343 | 0.0121450792942 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Long philtrum |
| HPA:043030_12 | 0.0121708949015 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | skin 1; keratinocytes[Supported,Medium] |
| HP:0007360 | 0.0125216870835 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Aplasia/Hypoplasia of the cerebellum |
| HPA:031020_11 | 0.0125823524493 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | ovary; ovarian stroma cells[Supported,Low] |
| HP:0030669 | 0.0126690181104 | 0.6 | STAG1 BANF1 SMC1A RAD21 STAG2 SMC3 | Abnormal ocular adnexa morphology |
| HP:0000736 | 0.0127131941594 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Short attention span |
| GO:0051225 | 0.0127317909148 | 0.4 | STAG1 SMC1A SMC3 STAG2 | spindle assembly |
| HPA:006010_11 | 0.0131765734396 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | caudate; glial cells[Supported,Low] |
| HPA:031010_12 | 0.0136676763663 | 0.4 | PDS5B SMC1A RAD21 STAG2 | ovary; follicle cells[Supported,Medium] |
| HP:0032039 | 0.0138493644561 | 0.6 | STAG1 BANF1 SMC1A RAD21 STAG2 SMC3 | Abnormality of the ocular adnexa |
| HPA:036010_12 | 0.0142460571805 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | prostate; glandular cells[Supported,Medium] |
| HPA:014020_12 | 0.0142460571805 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | endometrium 2; glandular cells[Supported,Medium] |
| HPA:056030_12 | 0.0142460571805 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | tonsil; squamous epithelial cells[Supported,Medium] |
| HPA:008010_13 | 0.0143688578318 | 0.3 | STAG1 RAD21 PDS5B | cerebral cortex; endothelial cells[Supported,High] |
| HPA:030010_12 | 0.0144307058064 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | oral mucosa; squamous epithelial cells[Supported,Medium] |
| HPA:013010_11 | 0.0147111784574 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | endometrium 1; cells in endometrial stroma[Supported,Low] |
| HPA:043010_02 | 0.0147386491404 | 0.6 | STAG1 PDS5B SMC1A RAD21 STAG2 SMC3 | skin 1; Langerhans[Uncertain,Medium] |
| HPA:008030_12 | 0.0148056092875 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | cerebral cortex; neuronal cells[Supported,Medium] |
| HP:0000315 | 0.0152832282365 | 0.6 | STAG1 BANF1 SMC1A RAD21 STAG2 SMC3 | Abnormality of the orbital region |
| HPA:039010_12 | 0.015479957195 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | salivary gland; glandular cells[Supported,Medium] |
| HPA:056030_13 | 0.0155532158161 | 0.4 | STAG1 SMC1A RAD21 PDS5B | tonsil; squamous epithelial cells[Supported,High] |
| HP:0002714 | 0.0156973266687 | 0.3 | RAD21 SMC3 SMC1A | Downturned corners of mouth |
| HP:0010049 | 0.0156973266687 | 0.3 | RAD21 SMC3 SMC1A | Short metacarpal |
| HP:0000786 | 0.0156973266687 | 0.3 | RAD21 SMC3 SMC1A | Primary amenorrhea |
| GO:0072686 | 0.0158370595379 | 0.4 | STAG1 SMC1A SMC3 STAG2 | mitotic spindle |
| HPA:007020_11 | 0.0158759233618 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | cerebellum; cells in granular layer[Supported,Low] |
| HPA:032020_03 | 0.0158850988027 | 0.4 | STAG1 SMC1A RAD21 STAG2 | pancreas; islets of Langerhans[Uncertain,High] |
| HPA:043010_11 | 0.016076848457 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | skin 1; Langerhans[Supported,Low] |
| HPA:008020_11 | 0.0161780525291 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | cerebral cortex; glial cells[Supported,Low] |
| HPA:013020_12 | 0.0169004845213 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | endometrium 1; glandular cells[Supported,Medium] |
| HPA:014010_02 | 0.0172176960007 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | endometrium 2; cells in endometrial stroma[Uncertain,Medium] |
| HP:0001376 | 0.0172571136557 | 0.4 | RAD21 SMC1A SMC3 BANF1 | Limitation of joint mobility |
| GO:0007052 | 0.0179524301545 | 0.4 | STAG1 SMC1A SMC3 STAG2 | mitotic spindle organization |
| HPA:053010_12 | 0.0179759331361 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | testis; Leydig cells[Supported,Medium] |
| HP:0000574 | 0.0179940984144 | 0.3 | RAD21 SMC3 SMC1A | Thick eyebrow |
| HP:0009601 | 0.0179940984144 | 0.3 | RAD21 SMC3 SMC1A | Aplasia/Hypoplasia of the thumb |
| HP:0009122 | 0.0185777465808 | 0.5 | STAG2 SMC1A SMC3 RAD21 BANF1 | Aplasia/hypoplasia affecting bones of the axial skeleton |
| HP:0100238 | 0.0186009560916 | 0.3 | RAD21 SMC3 SMC1A | Synostosis involving bones of the upper limbs |
| HPA:040010_12 | 0.0186463636539 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | seminal vesicle; glandular cells[Supported,Medium] |
| HPA:002020_11 | 0.0187599722758 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | appendix; lymphoid tissue[Supported,Low] |
| HPA:024010_11 | 0.0187599722758 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | kidney; cells in glomeruli[Supported,Low] |
| HPA:007030_11 | 0.0191040403666 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | cerebellum; cells in molecular layer[Supported,Low] |
| HPA:006020_11 | 0.0192198165307 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | caudate; neuronal cells[Supported,Low] |
| HPA:016010_12 | 0.0192198165307 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | esophagus; squamous epithelial cells[Supported,Medium] |
| HP:0001385 | 0.0192211576021 | 0.3 | RAD21 SMC3 SMC1A | Hip dysplasia |
| HPA:032020_11 | 0.0193361391332 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | pancreas; islets of Langerhans[Supported,Low] |
| HPA:044010_12 | 0.019453010002 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | skin 2; epidermal cells[Supported,Medium] |
| HP:0000453 | 0.0198548415518 | 0.3 | RAD21 SMC3 SMC1A | Choanal atresia |
| HP:0000664 | 0.0198548415518 | 0.3 | RAD21 SMC3 SMC1A | Synophrys |
| HPA:009020_11 | 0.0201658516121 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | cervix, uterine; squamous epithelial cells[Supported,Low] |
| HP:0002360 | 0.0203374120668 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Sleep disturbance |
| HPA:004020_12 | 0.0204079350423 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | breast; glandular cells[Supported,Medium] |
| HP:0002983 | 0.0205021463394 | 0.3 | RAD21 SMC3 SMC1A | Micromelia |
| HPA:011010_11 | 0.0205298231385 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | colon; endothelial cells[Supported,Low] |
| HPA:009010_11 | 0.0206522779712 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | cervix, uterine; glandular cells[Supported,Low] |
| HPA:041010_11 | 0.0210230615647 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | skeletal muscle; myocytes[Supported,Low] |
| HP:0000003 | 0.0211632101569 | 0.3 | RAD21 SMC3 SMC1A | Multicystic kidney dysplasia |
| HP:0005914 | 0.0211632101569 | 0.3 | RAD21 SMC3 SMC1A | Aplasia/Hypoplasia involving the metacarpal bones |
| HPA:009020_02 | 0.0211724030719 | 0.6 | STAG1 PDS5B SMC1A RAD21 STAG2 SMC3 | cervix, uterine; squamous epithelial cells[Uncertain,Medium] |
| HPA:004010_12 | 0.0215122205303 | 0.4 | STAG1 STAG2 RAD21 PDS5B | breast; adipocytes[Supported,Medium] |
| HPA:046010_11 | 0.0215254875973 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | smooth muscle; smooth muscle cells[Supported,Low] |
| HPA:004010_13 | 0.0215757878406 | 0.3 | STAG1 RAD21 PDS5B | breast; adipocytes[Supported,High] |
| HPA:015010_12 | 0.0219084090277 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | epididymis; glandular cells[Supported,Medium] |
| HPA:050010_11 | 0.0220372218764 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | spleen; cells in red pulp[Supported,Low] |
| HPA:055010_12 | 0.0220372218764 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | thyroid gland; glandular cells[Supported,Medium] |
| HPA:004030_11 | 0.0221666240815 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | breast; myoepithelial cells[Supported,Low] |
| HPA:032010_12 | 0.0222966175504 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | pancreas; exocrine glandular cells[Supported,Medium] |
| HPA:043040_11 | 0.0224272041942 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | skin 1; melanocytes[Supported,Low] |
| HPA:001040_12 | 0.0224272041942 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | adrenal gland; glandular cells[Supported,Medium] |
| HPA:027020_11 | 0.0224272041942 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | lung; pneumocytes[Supported,Low] |
| HP:0001773 | 0.0225271666167 | 0.3 | RAD21 SMC3 SMC1A | Short foot |
| HPA:002010_12 | 0.0228225423354 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | appendix; glandular cells[Supported,Medium] |
| HPA:035020_12 | 0.0228225423354 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | placenta; trophoblastic cells[Supported,Medium] |
| HPA:007010_11 | 0.0232232881754 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | cerebellum; Purkinje cells[Supported,Low] |
| HP:0000415 | 0.0232303346105 | 0.3 | RAD21 SMC3 SMC1A | Abnormality of the choanae |
| HP:0002219 | 0.0232303346105 | 0.3 | RAD21 SMC3 SMC1A | Facial hypertrichosis |
| HPA:033010_11 | 0.0233580808393 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | parathyroid gland; glandular cells[Supported,Low] |
| HPA:022020_11 | 0.0237661181236 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | hippocampus; neuronal cells[Supported,Low] |
| HP:0002230 | 0.0239478123375 | 0.3 | RAD21 SMC3 SMC1A | Generalized hirsutism |
| HPA:011010_02 | 0.0255057750446 | 0.6 | STAG1 PDS5B SMC1A RAD21 STAG2 SMC3 | colon; endothelial cells[Uncertain,Medium] |
| HPA:015010_13 | 0.0257567964145 | 0.4 | STAG1 STAG2 RAD21 PDS5B | epididymis; glandular cells[Supported,High] |
| HPA:021010_11 | 0.02663024958 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | heart muscle; myocytes[Supported,Low] |
| HPA:043040_02 | 0.0268526038007 | 0.6 | STAG1 PDS5B SMC1A RAD21 STAG2 SMC3 | skin 1; melanocytes[Uncertain,Medium] |
| HP:0000164 | 0.0270512166239 | 0.5 | STAG1 SMC1A SMC3 RAD21 BANF1 | Abnormality of the dentition |
| HP:0004097 | 0.0273504190316 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Deviation of finger |
| HPA:028020_11 | 0.0273865401789 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | lymph node; non-germinal center cells[Supported,Low] |
| HPA:052010_12 | 0.0276936921059 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | stomach 2; glandular cells[Supported,Medium] |
| HPA:011020_12 | 0.0276936921059 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | colon; glandular cells[Supported,Medium] |
| HPA:057010_12 | 0.0276936921059 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | urinary bladder; urothelial cells[Supported,Medium] |
| HPA:005010_12 | 0.0276936921059 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | bronchus; respiratory epithelial cells[Supported,Medium] |
| HPA:056030_11 | 0.0278482695801 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | tonsil; squamous epithelial cells[Supported,Low] |
| HPA:018010_12 | 0.0278482695801 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | fallopian tube; glandular cells[Supported,Medium] |
| HP:0004207 | 0.0283812039464 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Abnormal 5th finger morphology |
| HPA:051010_12 | 0.0286312539994 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | stomach 1; glandular cells[Supported,Medium] |
| HPA:058010_11 | 0.0286312539994 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | vagina; squamous epithelial cells[Supported,Low] |
| HPA:024020_12 | 0.0289491981238 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | kidney; cells in tubules[Supported,Medium] |
| HPA:048010_12 | 0.028993841744 | 0.4 | STAG1 STAG2 RAD21 PDS5B | soft tissue 2; adipocytes[Supported,Medium] |
| HP:0000277 | 0.0292668922809 | 0.5 | STAG2 SMC1A SMC3 RAD21 BANF1 | Abnormality of the mandible |
| HPA:045010_12 | 0.0294312556459 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | small intestine; glandular cells[Supported,Medium] |
| HPA:008030_11 | 0.0294312556459 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | cerebral cortex; neuronal cells[Supported,Low] |
| GO:0000922 | 0.0296393347717 | 0.4 | STAG1 SMC1A SMC3 STAG2 | spindle pole |
| HPA:043030_11 | 0.0297560791171 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | skin 1; keratinocytes[Supported,Low] |
| HPA:035020_03 | 0.0299195326417 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | placenta; trophoblastic cells[Uncertain,High] |
| HPA:056020_11 | 0.0299195326417 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | tonsil; non-germinal center cells[Supported,Low] |
| HPA:004030_02 | 0.0299497235493 | 0.6 | STAG1 PDS5B SMC1A RAD21 STAG2 SMC3 | breast; myoepithelial cells[Uncertain,Medium] |
| HPA:037010_12 | 0.0300836834791 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | rectum; glandular cells[Supported,Medium] |
| HP:0000752 | 0.0301623718522 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Hyperactivity |
| HP:0010938 | 0.0305339103252 | 0.5 | STAG2 SMC1A SMC3 RAD21 BANF1 | Abnormality of the external nose |
| HPA:030010_11 | 0.0307473018966 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | oral mucosa; squamous epithelial cells[Supported,Low] |
| HP:0001622 | 0.0310716135242 | 0.3 | RAD21 SMC3 SMC1A | Premature birth |
| HPA:014020_11 | 0.0312524404652 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | endometrium 2; glandular cells[Supported,Low] |
| HPA:019010_12 | 0.0312524404652 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | gallbladder; glandular cells[Supported,Medium] |
| HPA:012010_12 | 0.0312524404652 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | duodenum; glandular cells[Supported,Medium] |
| HP:0009484 | 0.031269787984 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Deviation of the hand or of fingers of the hand |
| HP:0001608 | 0.031269787984 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Abnormality of the voice |
| HP:0040070 | 0.031269787984 | 0.4 | RAD21 SMC1A SMC3 BANF1 | Abnormal upper limb bone morphology |
| HP:0000366 | 0.0314142681298 | 0.6 | STAG1 BANF1 SMC1A RAD21 STAG2 SMC3 | Abnormality of the nose |
| HPA:027010_11 | 0.0315927668105 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | lung; macrophages[Supported,Low] |
| HPA:036010_11 | 0.0319359668097 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | prostate; glandular cells[Supported,Low] |
| HPA:031020_02 | 0.0319359668097 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | ovary; ovarian stroma cells[Uncertain,Medium] |
| HPA:039010_11 | 0.0326310560094 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | salivary gland; glandular cells[Supported,Low] |
| HPA:040010_11 | 0.0329829794679 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | seminal vesicle; glandular cells[Supported,Low] |
| HPA:031010_11 | 0.0330875671623 | 0.4 | PDS5B SMC1A RAD21 STAG2 | ovary; follicle cells[Supported,Low] |
| HPA:001040_03 | 0.0335163866185 | 0.5 | STAG1 SMC1A SMC3 RAD21 PDS5B | adrenal gland; glandular cells[Uncertain,High] |
| HPA:013020_11 | 0.0335163866185 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | endometrium 1; glandular cells[Supported,Low] |
| HP:0000482 | 0.0337234250151 | 0.3 | RAD21 SMC3 SMC1A | Microcornea |
| HP:0002021 | 0.0337234250151 | 0.3 | RAD21 SMC3 SMC1A | Pyloric stenosis |
| HPA:055010_11 | 0.0342379946156 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | thyroid gland; glandular cells[Supported,Low] |
| HPA:004020_11 | 0.0342379946156 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | breast; glandular cells[Supported,Low] |
| HPA:016010_11 | 0.0344202679535 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | esophagus; squamous epithelial cells[Supported,Low] |
| HPA:044010_11 | 0.0346032941835 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | skin 2; epidermal cells[Supported,Low] |
| HPA:055010_13 | 0.0348376597882 | 0.4 | STAG1 SMC1A RAD21 PDS5B | thyroid gland; glandular cells[Supported,High] |
| HPA:043030_02 | 0.0352641435969 | 0.6 | STAG1 PDS5B SMC1A RAD21 STAG2 SMC3 | skin 1; keratinocytes[Uncertain,Medium] |
| HPA:002010_11 | 0.0353429717627 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | appendix; glandular cells[Supported,Low] |
| HPA:032010_11 | 0.035905742692 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | pancreas; exocrine glandular cells[Supported,Low] |
| HPA:001040_11 | 0.036475447815 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | adrenal gland; glandular cells[Supported,Low] |
| HP:0000055 | 0.0365199266312 | 0.3 | RAD21 SMC3 SMC1A | Abnormality of female external genitalia |
| HP:0004400 | 0.0365199266312 | 0.3 | RAD21 SMC3 SMC1A | Abnormality of the pylorus |
| HP:0002683 | 0.0367767358853 | 0.5 | STAG2 SMC1A SMC3 RAD21 BANF1 | Abnormality of the calvaria |
| WP:WP3959 | 0.0369034425738 | 0.2 | SMC3 SMC1A | DNA IR-Double Strand Breaks (DSBs) and cellular response via ATM |
| HPA:035020_11 | 0.0372459445976 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | placenta; trophoblastic cells[Supported,Low] |
| HP:0030791 | 0.0372760216168 | 0.5 | STAG2 SMC1A SMC3 RAD21 BANF1 | Abnormal jaw morphology |
| HPA:053010_11 | 0.0374405282662 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | testis; Leydig cells[Supported,Low] |
| HPA:018010_11 | 0.0374405282662 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | fallopian tube; glandular cells[Supported,Low] |
| HP:0001508 | 0.0380348731164 | 0.5 | STAG2 SMC1A SMC3 RAD21 BANF1 | Failure to thrive |
| HPA:015010_11 | 0.0382267679178 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | epididymis; glandular cells[Supported,Low] |
| HP:0000954 | 0.0384664357231 | 0.3 | RAD21 SMC3 SMC1A | Single transverse palmar crease |
| HP:0000141 | 0.0384664357231 | 0.3 | RAD21 SMC3 SMC1A | Amenorrhea |
| HP:0000422 | 0.0388057518597 | 0.5 | STAG1 SMC1A SMC3 RAD21 STAG2 | Abnormality of the nasal bridge |
| HPA:006010_02 | 0.038824810785 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | caudate; glial cells[Uncertain,Medium] |
| HPA:011020_11 | 0.038824810785 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | colon; glandular cells[Supported,Low] |
| HPA:041010_02 | 0.0388311147951 | 0.6 | STAG1 PDS5B SMC1A RAD21 STAG2 SMC3 | skeletal muscle; myocytes[Uncertain,Medium] |
| GO:1902850 | 0.0391967347834 | 0.4 | STAG1 SMC1A SMC3 STAG2 | microtubule cytoskeleton organization involved in mitosis |
| HPA:057010_11 | 0.0394300897283 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | urinary bladder; urothelial cells[Supported,Low] |
| HPA:019010_11 | 0.0394300897283 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | gallbladder; glandular cells[Supported,Low] |
| HP:0000076 | 0.0394647443381 | 0.3 | RAD21 SMC3 SMC1A | Vesicoureteral reflux |
| HPA:057010_13 | 0.0395078550689 | 0.4 | PDS5B SMC1A RAD21 STAG2 | urinary bladder; urothelial cells[Supported,High] |
| HPA:001040_13 | 0.0395078550689 | 0.4 | STAG1 SMC1A RAD21 PDS5B | adrenal gland; glandular cells[Supported,High] |
| HPA:008010_12 | 0.0395078550689 | 0.4 | STAG1 SMC1A RAD21 PDS5B | cerebral cortex; endothelial cells[Supported,Medium] |
| HPA:005010_11 | 0.0396334679653 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | bronchus; respiratory epithelial cells[Supported,Low] |
| HPA:037010_11 | 0.0398376592841 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | rectum; glandular cells[Supported,Low] |
| GO:0010564 | 0.0400302955011 | 0.6 | STAG1 STAG2 SMC1A RAD21 CDCA5 SMC3 | regulation of cell cycle process |
| HPA:058010_02 | 0.0405729569439 | 0.6 | STAG1 PDS5B SMC1A RAD21 STAG2 SMC3 | vagina; squamous epithelial cells[Uncertain,Medium] |
| HPA:051010_11 | 0.0406626009815 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | stomach 1; glandular cells[Supported,Low] |
| HP:0002997 | 0.0415121371171 | 0.3 | RAD21 SMC3 SMC1A | Abnormality of the ulna |
| HP:0030084 | 0.041698812194 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Clinodactyly |
| HPA:052010_11 | 0.0423522079783 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | stomach 2; glandular cells[Supported,Low] |
| HPA:012010_11 | 0.0425671778734 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | duodenum; glandular cells[Supported,Low] |
| HPA:045010_11 | 0.0429996558327 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | small intestine; glandular cells[Supported,Low] |
| HPA:022010_12 | 0.044264016055 | 0.4 | PDS5B SMC1A RAD21 STAG2 | hippocampus; glial cells[Supported,Medium] |
| HP:0005280 | 0.0450278518397 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Depressed nasal bridge |
| HP:0000729 | 0.0450278518397 | 0.4 | STAG2 SMC1A SMC3 RAD21 | Autistic behavior |
| HPA:024020_11 | 0.0456665738307 | 0.5 | STAG1 SMC1A STAG2 RAD21 PDS5B | kidney; cells in tubules[Supported,Low] |
| HP:0005916 | 0.0458137496085 | 0.3 | RAD21 SMC3 SMC1A | Abnormal metacarpal morphology |
| HPA:005010_13 | 0.0460595555119 | 0.4 | STAG1 SMC1A RAD21 PDS5B | bronchus; respiratory epithelial cells[Supported,High] |
| HPA:048030_13 | 0.0467028249773 | 0.3 | STAG1 RAD21 PDS5B | soft tissue 2; fibroblasts[Supported,High] |
| HPA:058010_03 | 0.0475337334079 | 0.4 | STAG1 SMC1A RAD21 PDS5B | vagina; squamous epithelial cells[Uncertain,High] |
| CORUM:1989 | 0.0499561984052 | 0.1 | BANF1 | BANF1 homodimer protein |
| CORUM:6148 | 0.0499561984052 | 0.1 | BANF1 | BAFL-BAF complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SMC3 | SMC1A | 1.0 | 0.949 | hein_WMM bioplex_WMM boldt youn_WMM hein (SMC1A,SMC3) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| PDS5B | PDS5A | 1.0 | 0.949 | hein_WMM bioplex_WMM youn_WMM Malo gupta_WMM fraction treiber_WMM |
| SMC3 | SMC1B | 0.998 | 0.938 | bioplex_WMM Malo fraction |
| PDS5B | SMC1A | 0.998 | 0.937 | hein_WMM bioplex_WMM youn_WMM hein (SMC1A) Malo gupta_WMM fraction treiber_WMM |
| RAD21 | SMC1B | 0.998 | 0.937 | bioplex (RAD21) bioplex_WMM Malo fraction |
| STAG2 | SMC1B | 0.998 | 0.937 | bioplex_WMM Malo fraction |
| STAG1 | SMC1B | 0.997 | 0.935 | bioplex_WMM Malo fraction |
| PDS5A | SMC1A | 0.996 | 0.928 | hein_WMM bioplex_WMM youn_WMM hein (SMC1A) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| STAG2 | PDS5A | 0.996 | 0.927 | hein_WMM bioplex_WMM boldt youn_WMM Malo fraction boldt_WMM |
| RAD21 | SMC1A | 0.995 | 0.924 | hein_WMM bioplex (RAD21) bioplex_WMM youn_WMM hein (RAD21,SMC1A) Malo gupta_WMM fraction boldt_WMM |
| STAG1 | RAD21 | 0.994 | 0.923 | hein_WMM bioplex (RAD21) bioplex_WMM hein (RAD21) Malo fraction |
| SMC3 | PDS5A | 0.993 | 0.918 | hein_WMM bioplex_WMM boldt youn_WMM hein (SMC3) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| SMC3 | RAD21 | 0.989 | 0.905 | hein_WMM bioplex (RAD21) bioplex_WMM youn_WMM hein (RAD21,SMC3) Malo gupta_WMM fraction boldt_WMM |
| STAG1 | PDS5B | 0.988 | 0.902 | hein_WMM bioplex_WMM Malo fraction |
| RAD21 | CDCA5 | 0.988 | 0.902 | hein_WMM bioplex (CDCA5) bioplex_WMM youn_WMM hein (CDCA5,RAD21) |
| SMC3 | PDS5B | 0.988 | 0.901 | hein_WMM bioplex_WMM youn_WMM hein (SMC3) Malo gupta_WMM fraction treiber_WMM |
| STAG2 | RAD21 | 0.98 | 0.896 | hein_WMM bioplex (RAD21) bioplex_WMM youn_WMM hein (RAD21) Malo fraction boldt_WMM |
| STAG2 | SMC1A | 0.754 | 0.748 | hein_WMM bioplex_WMM boldt youn_WMM hein (SMC1A) Malo gupta_WMM fraction boldt_WMM |
| STAG1 | SMC1A | 0.714 | 0.727 | hein_WMM bioplex_WMM hein (SMC1A) Malo fraction |
| PDS5B | RAD21 | 0.637 | 0.685 | hein_WMM bioplex (RAD21) bioplex_WMM youn_WMM hein (RAD21) gupta_WMM |
| SMC3 | STAG2 | 0.6 | 0.671 | hein_WMM bioplex_WMM boldt youn_WMM hein (SMC3) Malo gupta_WMM fraction boldt_WMM |
| STAG2 | CDCA5 | 0.591 | 0.664 | hein_WMM bioplex (CDCA5) bioplex_WMM youn_WMM hein (CDCA5) |
| SMC3 | CDCA5 | 0.354 | 0.539 | hein_WMM bioplex (CDCA5) bioplex_WMM youn_WMM hein (CDCA5,SMC3) |
| SMC1A | CDCA5 | 0.247 | 0.471 | hein_WMM bioplex (CDCA5) bioplex_WMM youn_WMM hein (CDCA5,SMC1A) |
| SMC3 | BANF1 | 0.156 | 0.415 | bioplex_WMM gupta_WMM fraction |
| RAD21 | PDS5A | 0.143 | 0.405 | hein_WMM bioplex (RAD21) bioplex_WMM youn_WMM hein (RAD21) gupta_WMM |
| STAG1 | SMC3 | 0.089 | 0.352 | hein_WMM bioplex_WMM hein (SMC3) Malo fraction |
| STAG1 | CDCA5 | 0.023 | 0.211 | hein_WMM hein (CDCA5) |
| STAG1 | STAG2 | 0.021 | 0.188 | hein_WMM bioplex_WMM WMM_only |
| CDCA5 | SMC1B | 0.02 | 0.188 | bioplex (CDCA5) bioplex_WMM |
| PDS5B | CDCA5 | 0.013 | 0.155 | hein_WMM youn_WMM hein (CDCA5) |
| PDS5B | STAG2 | 0.01 | 0.137 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| STAG1 | PDS5A | 0.01 | 0.097 | hein_WMM bioplex_WMM WMM_only |
| SMC1A | SMC1B | 0.009 | 0.103 | bioplex_WMM WMM_only |
| PDS5A | SMC1B | 0.007 | 0.006 | bioplex_WMM WMM_only |
| PDS5B | SMC1B | 0.007 | 0.008 | bioplex_WMM WMM_only |
| PDS5A | CDCA5 | 0.007 | 0.009 | hein_WMM youn_WMM hein (CDCA5) |
| BANF1 | RAD21 | 0.006 | 0.002 | bioplex_WMM fraction |
| BANF1 | SMC1A | 0.004 | 0.014 | bioplex_WMM gupta_WMM fraction boldt_WMM |
Images
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Complex HuMAP2_00301 has an average edge precision of 0.577 which is ranked 2048 out of all 6965 complexes.
Related Complexes