hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00305
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ALDH6A1 | Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (MMSDH) (Malonate-semialdehyde dehydrogenase [acylating]) (EC 1.2.1.18) (EC 1.2.1.27) (Aldehyde dehydrogenase family 6 member A1) | UniProt NCBI |
| ALDH2 | Aldehyde dehydrogenase, mitochondrial (EC 1.2.1.3) (ALDH class 2) (ALDH-E2) (ALDHI) | UniProt NCBI |
| PEPD | Xaa-Pro dipeptidase (X-Pro dipeptidase) (EC 3.4.13.9) (Imidodipeptidase) (Peptidase D) (Proline dipeptidase) (Prolidase) | UniProt NCBI |
| ME2 | NAD-dependent malic enzyme, mitochondrial (NAD-ME) (EC 1.1.1.38) (Malic enzyme 2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00410 | 0.000869408386689 | 0.5 | ALDH6A1 ALDH2 | beta-Alanine metabolism |
| KEGG:00620 | 0.00147979776218 | 0.5 | ME2 ALDH2 | Pyruvate metabolism |
| KEGG:00280 | 0.00215723904775 | 0.5 | ALDH6A1 ALDH2 | Valine, leucine and isoleucine degradation |
| KEGG:01200 | 0.012776519361 | 0.5 | ALDH6A1 ME2 | Carbon metabolism |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ALDH2 | ALDH6A1 | 1.0 | 0.949 | bioplex (ALDH2) bioplex_WMM fraction |
| ALDH6A1 | PEPD | 0.877 | 0.811 | fraction |
| ALDH2 | ME2 | 0.816 | 0.773 | bioplex_WMM fraction |
| ALDH2 | PEPD | 0.709 | 0.728 | bioplex_WMM fraction treiber_WMM |
| ME2 | PEPD | 0.0 | 0.009 | bioplex_WMM fraction |
Images
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Complex HuMAP2_00305 has an average edge precision of 0.654 which is ranked 1629 out of all 6965 complexes.
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