hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00307
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MGME1 | Mitochondrial genome maintenance exonuclease 1 (EC 3.1.-.-) | UniProt NCBI |
| PALLD | Palladin (SIH002) (Sarcoma antigen NY-SAR-77) | UniProt NCBI |
| IMPA2 | Inositol monophosphatase 2 (IMP 2) (IMPase 2) (EC 3.1.3.25) (Inositol-1(or 4)-monophosphatase 2) (Myo-inositol monophosphatase A2) | UniProt NCBI |
| GRPEL1 | GrpE protein homolog 1, mitochondrial (HMGE) (Mt-GrpE#1) | UniProt NCBI |
| TRIM45 | Tripartite motif-containing protein 45 (RING finger protein 99) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0004396 | 0.0162585949147 | 0.4 | PALLD MGME1 | Poor appetite |
| CORUM:7123 | 0.0499494897235 | 0.2 | GRPEL1 | GRPEL1-GRPEL2 complex |
| CORUM:7124 | 0.0499494897235 | 0.2 | GRPEL1 | HSPA9-GRPEL1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MGME1 | TRIM45 | 0.629 | 0.681 | bioplex (MGME1) bioplex_WMM |
| MGME1 | GRPEL1 | 0.243 | 0.468 | bioplex (MGME1) bioplex_WMM youn_WMM fraction |
| PALLD | GRPEL1 | 0.067 | 0.351 | hein_WMM bioplex (GRPEL1) bioplex_WMM youn_WMM gupta_WMM fraction |
| IMPA2 | GRPEL1 | 0.049 | 0.294 | Guru fraction |
| MGME1 | PALLD | 0.007 | 0.003 | youn_WMM WMM_only |
| GRPEL1 | TRIM45 | 0.007 | 0.002 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_00307 has an average edge precision of 0.3 which is ranked 4598 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MGME1 | HuMAP2_00307 HuMAP2_02275 HuMAP2_03324 HuMAP2_04653 HuMAP2_06336 |
| PALLD | HuMAP2_00307 HuMAP2_03324 HuMAP2_04816 |
| IMPA2 | HuMAP2_00307 HuMAP2_03324 HuMAP2_04111 |
| GRPEL1 | HuMAP2_00307 HuMAP2_00358 HuMAP2_00502 HuMAP2_03324 |
| TRIM45 | HuMAP2_00307 HuMAP2_01481 HuMAP2_02275 HuMAP2_03032 HuMAP2_03324 HuMAP2_04653 HuMAP2_06336 |