hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_00324
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| LSM1 | U6 snRNA-associated Sm-like protein LSm1 (Cancer-associated Sm-like) (Small nuclear ribonuclear CaSm) | UniProt NCBI |
| PAPSS2 | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (PAPS synthase 2) (PAPSS 2) (Sulfurylase kinase 2) (SK 2) (SK2) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (ATP-sulfurylase) (Sulfate adenylate transferase) (SAT); Adenylyl-sulfate kinase (EC 2.7.1.25) (3'-phosphoadenosine-5'-phosphosulfate synthase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (Adenylylsulfate 3'-phosphotransferase)] | UniProt NCBI |
| CDC37 | Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) [Cleaved into: Hsp90 co-chaperone Cdc37, N-terminally processed] | UniProt NCBI |
| FTSJ1 | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase (EC 2.1.1.205) (2'-O-ribose RNA methyltransferase TRM7 homolog) (Protein ftsJ homolog 1) | UniProt NCBI |
| WDR6 | WD repeat-containing protein 6 | UniProt NCBI |
| PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase regulatory subunit beta) (PI3K regulatory subunit beta) (PtdIns-3-kinase regulatory subunit beta) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta) (PI3-kinase subunit p85-beta) (PtdIns-3-kinase regulatory subunit p85-beta) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2018 | 0.00734453778716 | 0.333333333333 | PAPSS2 PIK3R2 | RANKL/RANK (Receptor activator of NFKB (ligand)) Signaling Pathway |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| WDR6 | FTSJ1 | 1.0 | 0.949 | hein_WMM bioplex (FTSJ1) bioplex_WMM boldt youn_WMM hein (FTSJ1) gupta_WMM fraction boldt_WMM |
| WDR6 | PIK3R2 | 0.076 | 0.357 | bioplex (PIK3R2) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| LSM1 | CDC37 | 0.051 | 0.296 | youn (LSM1) youn_WMM fraction |
| FTSJ1 | PIK3R2 | 0.048 | 0.293 | bioplex (PIK3R2) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| PAPSS2 | WDR6 | 0.045 | 0.291 | bioplex (WDR6) bioplex_WMM |
| CDC37 | FTSJ1 | 0.045 | 0.286 | hein_WMM bioplex (FTSJ1) bioplex_WMM youn_WMM hein (CDC37,FTSJ1) gupta_WMM |
| LSM1 | FTSJ1 | 0.007 | 0.001 | youn_WMM WMM_only |
| LSM1 | WDR6 | 0.007 | 0.005 | boldt youn_WMM boldt_WMM |
| LSM1 | PIK3R2 | 0.006 | 0.003 | boldt youn_WMM boldt_WMM |
| CDC37 | PIK3R2 | 0.006 | 0.003 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| WDR6 | CDC37 | 0.005 | 0.006 | hein_WMM bioplex (WDR6) bioplex_WMM boldt youn_WMM hein (CDC37) gupta_WMM boldt_WMM |
Images
Click to enlarge
Complex HuMAP2_00324 has an average edge precision of 0.226 which is ranked 5756 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| LSM1 | HuMAP2_00104 HuMAP2_00225 HuMAP2_00324 HuMAP2_01515 HuMAP2_01710 HuMAP2_02497 HuMAP2_05007 |
| PAPSS2 | HuMAP2_00324 HuMAP2_01296 HuMAP2_02819 HuMAP2_03575 |
| CDC37 | HuMAP2_00324 HuMAP2_06797 |
| FTSJ1 | HuMAP2_00324 HuMAP2_03575 HuMAP2_05447 HuMAP2_06494 |
| WDR6 | HuMAP2_00324 HuMAP2_03575 HuMAP2_05447 HuMAP2_06494 |
| PIK3R2 | HuMAP2_00324 HuMAP2_00730 HuMAP2_02534 HuMAP2_02611 HuMAP2_05290 HuMAP2_06494 |