hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00325
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| HIST1H1T | Histone H1t (Testicular H1 histone) | UniProt NCBI |
| NVL | Nuclear valosin-containing protein-like (NVLp) (Nuclear VCP-like protein) | UniProt NCBI |
| BOP1 | Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein) | UniProt NCBI |
| PES1 | Pescadillo homolog | UniProt NCBI |
| WDR12 | Ribosome biogenesis protein WDR12 (WD repeat-containing protein 12) | UniProt NCBI |
| RPL7L1 | 60S ribosomal protein L7-like 1 (Large ribosomal subunit protein uL30-like 1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6856 | 2.25356268047e-09 | 0.5 | WDR12 PES1 BOP1 | PeBoW complex |
| CORUM:6306 | 9.01288868683e-09 | 0.5 | WDR12 PES1 BOP1 | DDX27-PeBoW complex |
| GO:0000463 | 2.61389419879e-07 | 0.666666666667 | RPL7L1 WDR12 PES1 BOP1 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| GO:0042273 | 3.4435733921e-07 | 0.833333333333 | BOP1 WDR12 RPL7L1 NVL PES1 | ribosomal large subunit biogenesis |
| GO:0000470 | 1.76990051719e-06 | 0.666666666667 | RPL7L1 WDR12 PES1 BOP1 | maturation of LSU-rRNA |
| GO:0070545 | 1.81582264982e-05 | 0.5 | WDR12 PES1 BOP1 | PeBoW complex |
| GO:0006364 | 5.93143067578e-05 | 0.833333333333 | BOP1 WDR12 RPL7L1 NVL PES1 | rRNA processing |
| GO:0016072 | 7.66174643411e-05 | 0.833333333333 | BOP1 WDR12 RPL7L1 NVL PES1 | rRNA metabolic process |
| GO:0042254 | 0.000277631504382 | 0.833333333333 | BOP1 WDR12 RPL7L1 NVL PES1 | ribosome biogenesis |
| GO:0034470 | 0.00120907776661 | 0.833333333333 | BOP1 WDR12 RPL7L1 NVL PES1 | ncRNA processing |
| GO:0022613 | 0.00270779091032 | 0.833333333333 | BOP1 WDR12 RPL7L1 NVL PES1 | ribonucleoprotein complex biogenesis |
| GO:0030687 | 0.0032070828615 | 0.5 | WDR12 PES1 BOP1 | preribosome, large subunit precursor |
| GO:0034660 | 0.00405016747169 | 0.833333333333 | BOP1 WDR12 RPL7L1 NVL PES1 | ncRNA metabolic process |
| REAC:R-HSA-6791226 | 0.00563418329838 | 0.5 | WDR12 PES1 BOP1 | Major pathway of rRNA processing in the nucleolus and cytosol |
| GO:0030686 | 0.00661098268806 | 0.5 | WDR12 PES1 BOP1 | 90S preribosome |
| REAC:R-HSA-8868773 | 0.00661628360681 | 0.5 | WDR12 PES1 BOP1 | rRNA processing in the nucleus and cytosol |
| REAC:R-HSA-72312 | 0.00770517770968 | 0.5 | WDR12 PES1 BOP1 | rRNA processing |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PES1 | BOP1 | 0.905 | 0.828 | bioplex (PES1) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| PES1 | WDR12 | 0.849 | 0.79 | bioplex (PES1) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| PES1 | RPL7L1 | 0.159 | 0.418 | hein_WMM bioplex (PES1) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| HIST1H1T | PES1 | 0.128 | 0.398 | bioplex (HIST1H1T) bioplex_WMM fraction |
| NVL | PES1 | 0.027 | 0.231 | hein_WMM bioplex (PES1) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| WDR12 | BOP1 | 0.019 | 0.186 | bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| NVL | RPL7L1 | 0.013 | 0.142 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| WDR12 | RPL7L1 | 0.013 | 0.148 | bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| BOP1 | RPL7L1 | 0.011 | 0.141 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| NVL | BOP1 | 0.009 | 0.109 | bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| NVL | WDR12 | 0.009 | 0.098 | bioplex_WMM youn_WMM WMM_only |
| HIST1H1T | RPL7L1 | 0.006 | 0.006 | bioplex (HIST1H1T) bioplex_WMM treiber_WMM |
| NVL | HIST1H1T | 0.004 | 0.007 | bioplex (HIST1H1T) bioplex_WMM |
| HIST1H1T | WDR12 | 0.004 | 0.014 | bioplex (HIST1H1T) bioplex_WMM |
| HIST1H1T | BOP1 | 0.004 | 0.005 | bioplex (HIST1H1T) bioplex_WMM |
Images
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Complex HuMAP2_00325 has an average edge precision of 0.235 which is ranked 5619 out of all 6965 complexes.
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