hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_00341
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TUBB | Tubulin beta chain (Tubulin beta-5 chain) | UniProt NCBI |
| TUBB4B | Tubulin beta-4B chain (Tubulin beta-2 chain) (Tubulin beta-2C chain) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2272 | 0.000494042845858 | 1.0 | TUBB TUBB4B | Pathogenic Escherichia coli infection |
| KEGG:04540 | 0.000508598838856 | 1.0 | TUBB TUBB4B | Gap junction |
| WP:WP2359 | 0.000799186956535 | 1.0 | TUBB TUBB4B | Parkin-Ubiquitin Proteasomal System pathway |
| KEGG:04145 | 0.00131964328671 | 1.0 | TUBB TUBB4B | Phagosome |
| KEGG:05130 | 0.00227250014745 | 1.0 | TUBB TUBB4B | Pathogenic Escherichia coli infection |
| REAC:R-HSA-380259 | 0.00370546677531 | 1.0 | TUBB TUBB4B | Loss of Nlp from mitotic centrosomes |
| REAC:R-HSA-380284 | 0.00370546677531 | 1.0 | TUBB TUBB4B | Loss of proteins required for interphase microtubule organization from the centrosome |
| REAC:R-HSA-8854518 | 0.00404735516163 | 1.0 | TUBB TUBB4B | AURKA Activation by TPX2 |
| REAC:R-HSA-380287 | 0.00516352018758 | 1.0 | TUBB TUBB4B | Centrosome maturation |
| REAC:R-HSA-380270 | 0.00516352018758 | 1.0 | TUBB TUBB4B | Recruitment of mitotic centrosome proteins and complexes |
| REAC:R-HSA-2565942 | 0.00584226918984 | 1.0 | TUBB TUBB4B | Regulation of PLK1 Activity at G2/M Transition |
| REAC:R-HSA-380320 | 0.00671207346681 | 1.0 | TUBB TUBB4B | Recruitment of NuMA to mitotic centrosomes |
| REAC:R-HSA-5620912 | 0.0074829982595 | 1.0 | TUBB TUBB4B | Anchoring of the basal body to the plasma membrane |
| GO:0042288 | 0.020287053512 | 1.0 | TUBB TUBB4B | MHC class I protein binding |
| REAC:R-HSA-69275 | 0.0300912057669 | 1.0 | TUBB TUBB4B | G2/M Transition |
| REAC:R-HSA-5617833 | 0.0304096312248 | 1.0 | TUBB TUBB4B | Cilium Assembly |
| REAC:R-HSA-68877 | 0.0304096312248 | 1.0 | TUBB TUBB4B | Mitotic Prometaphase |
| REAC:R-HSA-453274 | 0.0307297326061 | 1.0 | TUBB TUBB4B | Mitotic G2-G2/M phases |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TUBB | TUBB4B | 1.0 | 0.949 | hein_WMM bioplex (TUBB) boldt (TUBB4B) fraction boldt_WMM treiber_WMM bioplex_WMM |
Images
Click to enlarge
Complex HuMAP2_00341 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| TUBB | HuMAP2_00341 HuMAP2_01301 |
| TUBB4B | HuMAP2_00341 HuMAP2_01876 HuMAP2_05358 |