hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00351
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ABHD16A | Phosphatidylserine lipase ABHD16A (EC 3.1.-.-) (Alpha/beta hydrolase domain-containing protein 16A) (Abhydrolase domain-containing protein 16A) (HLA-B-associated transcript 5) (hBAT5) (Monoacylglycerol lipase ABHD16A) (EC 3.1.1.23) (Protein G5) | UniProt NCBI |
| ANKHD1 | Ankyrin repeat and KH domain-containing protein 1 (HIV-1 Vpr-binding ankyrin repeat protein) (Multiple ankyrin repeats single KH domain) (hMASK) | UniProt NCBI |
| ECI2 | Enoyl-CoA delta isomerase 2, mitochondrial (EC 5.3.3.8) (DRS-1) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (Diazepam-binding inhibitor-related protein 1) (DBI-related protein 1) (Dodecenoyl-CoA isomerase) (Hepatocellular carcinoma-associated antigen 88) (Peroxisomal 3,2-trans-enoyl-CoA isomerase) (pECI) (Renal carcinoma antigen NY-REN-1) | UniProt NCBI |
| STXBP2 | Syntaxin-binding protein 2 (Protein unc-18 homolog 2) (Unc18-2) (Protein unc-18 homolog B) (Unc-18B) | UniProt NCBI |
| ANXA3 | Annexin A3 (35-alpha calcimedin) (Annexin III) (Annexin-3) (Inositol 1,2-cyclic phosphate 2-phosphohydrolase) (Lipocortin III) (Placental anticoagulant protein III) (PAP-III) | UniProt NCBI |
| SCNN1D | Amiloride-sensitive sodium channel subunit delta (Delta-NaCH) (Epithelial Na(+) channel subunit delta) (Delta-ENaC) (ENaCD) (Nonvoltage-gated sodium channel 1 subunit delta) (SCNED) | UniProt NCBI |
| ECHS1 | Enoyl-CoA hydratase, mitochondrial (EC 4.2.1.17) (Enoyl-CoA hydratase 1) (Short-chain enoyl-CoA hydratase) (SCEH) | UniProt NCBI |
| STX11 | Syntaxin-11 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0012156 | 0.00348326758344 | 0.25 | STXBP2 STX11 | Hemophagocytosis |
| KEGG:00071 | 0.0103387036304 | 0.25 | ECI2 ECHS1 | Fatty acid degradation |
| HP:0003281 | 0.0253031982095 | 0.25 | STXBP2 STX11 | Increased serum ferritin |
| HP:0040133 | 0.0282724469862 | 0.25 | STXBP2 STX11 | Abnormal serum ferritin |
| HP:0004311 | 0.0495208749973 | 0.25 | STXBP2 STX11 | Abnormal macrophage morphology |
| CORUM:3196 | 0.0497224828424 | 0.125 | STX11 | FHL4/STX11-ACT complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| STXBP2 | STX11 | 0.659 | 0.696 | bioplex (STX11) bioplex_WMM |
| SCNN1D | STX11 | 0.049 | 0.294 | bioplex (STX11) bioplex_WMM |
| ABHD16A | SCNN1D | 0.041 | 0.27 | bioplex (SCNN1D) bioplex_WMM |
| STXBP2 | ECHS1 | 0.035 | 0.265 | fraction |
| ANXA3 | ECHS1 | 0.031 | 0.239 | fraction treiber_WMM |
| ECI2 | ECHS1 | 0.025 | 0.213 | bioplex_WMM youn_WMM fraction |
| ANKHD1 | STX11 | 0.023 | 0.208 | bioplex (STX11) bioplex_WMM |
| STXBP2 | SCNN1D | 0.008 | 0.047 | bioplex_WMM WMM_only |
| ANKHD1 | SCNN1D | 0.007 | 0.01 | bioplex_WMM WMM_only |
| ANKHD1 | STXBP2 | 0.007 | 0.001 | bioplex_WMM WMM_only |
| ANKHD1 | ECHS1 | 0.007 | 0.001 | bioplex_WMM WMM_only |
| ANKHD1 | ECI2 | 0.007 | 0.0 | bioplex_WMM WMM_only |
| STXBP2 | ECI2 | 0.0 | 0.013 | youn_WMM fraction |
Images
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Complex HuMAP2_00351 has an average edge precision of 0.174 which is ranked 6489 out of all 6965 complexes.
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