hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00354
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CIAO2B | Cytosolic iron-sulfur assembly component 2B (MSS19-interacting protein of 18 kDa) (Mitotic spindle-associated MMXD complex subunit MIP18) (Protein FAM96B) | UniProt NCBI |
| CIAO1 | Probable cytosolic iron-sulfur protein assembly protein CIAO1 (WD repeat-containing protein 39) | UniProt NCBI |
| MMS19 | MMS19 nucleotide excision repair protein homolog (hMMS19) (MET18 homolog) (MMS19-like protein) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:5495 | 2.25356268047e-10 | 1.0 | CIAO2B MMS19 CIAO1 | CIA targeting (MIP18, CIAO1, MMS19) complex |
| CORUM:6897 | 2.25356268047e-10 | 1.0 | CIAO2B MMS19 CIAO1 | CIA2B-CIA1-MMS19 complex |
| CORUM:6896 | 9.0142507219e-10 | 1.0 | CIAO2B MMS19 CIAO1 | MMS19 complex |
| CORUM:6895 | 2.25356268047e-09 | 1.0 | CIAO2B MMS19 CIAO1 | MMXD complex |
| REAC:R-HSA-2564830 | 1.28584716548e-07 | 1.0 | CIAO2B MMS19 CIAO1 | Cytosolic iron-sulfur cluster assembly |
| GO:0071817 | 9.08185760231e-07 | 1.0 | CIAO2B MMS19 CIAO1 | MMXD complex |
| GO:0097361 | 9.08185760231e-07 | 1.0 | CIAO2B MMS19 CIAO1 | CIA complex |
| CORUM:7223 | 3.35600554376e-06 | 0.666666666667 | CIAO2B MMS19 | MMS19-FAM96B complex |
| GO:0097428 | 2.59741127426e-05 | 1.0 | CIAO2B MMS19 CIAO1 | protein maturation by iron-sulfur cluster transfer |
| GO:0016226 | 0.000120788706111 | 1.0 | CIAO2B MMS19 CIAO1 | iron-sulfur cluster assembly |
| GO:0031163 | 0.000120788706111 | 1.0 | CIAO2B MMS19 CIAO1 | metallo-sulfur cluster assembly |
| CORUM:7222 | 0.0499776345577 | 0.333333333333 | MMS19 | MMS19-XPD complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CIAO2B | MMS19 | 1.0 | 0.949 | hein_WMM bioplex (MMS19) bioplex_WMM boldt youn_WMM hein (MMS19) boldt_WMM |
| MMS19 | CIAO1 | 1.0 | 0.949 | hein_WMM bioplex (MMS19) bioplex_WMM boldt youn_WMM hein (MMS19) fraction boldt_WMM |
| CIAO2B | CIAO1 | 0.021 | 0.185 | hein_WMM bioplex_WMM Guru boldt youn_WMM fraction boldt_WMM |
Images
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Complex HuMAP2_00354 has an average edge precision of 0.694 which is ranked 1396 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CIAO2B | HuMAP2_00354 HuMAP2_05732 |
| CIAO1 | HuMAP2_00354 HuMAP2_05732 |
| MMS19 | HuMAP2_00354 HuMAP2_05732 |