hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00357
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RB1CC1 | RB1-inducible coiled-coil protein 1 (FAK family kinase-interacting protein of 200 kDa) (FIP200) | UniProt NCBI |
| ATG101 | Autophagy-related protein 101 | UniProt NCBI |
| FAM221B | Protein FAM221B | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6232 | 2.01342304124e-05 | 0.666666666667 | RB1CC1 ATG101 | ULK1-ATG13-RB1CC1-ATG101 complex |
| CORUM:7091 | 2.01342304124e-05 | 0.666666666667 | RB1CC1 ATG101 | FIP200-ULK1-ATG13-ATG101 complex |
| CORUM:7065 | 7.04603414803e-05 | 0.666666666667 | RB1CC1 ATG101 | WDR41-(C9orf72-SMCR8)-(FIP200-ULK1-ATG13-ATG101) complex |
| WP:WP4577 | 0.000864566693143 | 0.666666666667 | RB1CC1 ATG101 | Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway |
| KEGG:04211 | 0.00148194300046 | 0.666666666667 | RB1CC1 ATG101 | Longevity regulating pathway |
| KEGG:04140 | 0.00390806659107 | 0.666666666667 | RB1CC1 ATG101 | Autophagy - animal |
| REAC:R-HSA-1632852 | 0.0249521708712 | 0.666666666667 | RB1CC1 ATG101 | Macroautophagy |
| REAC:R-HSA-9612973 | 0.0350118981581 | 0.666666666667 | RB1CC1 ATG101 | Autophagy |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RB1CC1 | FAM221B | 0.234 | 0.47 | bioplex (FAM221B) bioplex_WMM |
| ATG101 | FAM221B | 0.187 | 0.44 | bioplex (FAM221B) bioplex_WMM |
| RB1CC1 | ATG101 | 0.009 | 0.107 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_00357 has an average edge precision of 0.339 which is ranked 4137 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RB1CC1 | HuMAP2_00357 HuMAP2_03547 HuMAP2_03911 |
| ATG101 | HuMAP2_00357 HuMAP2_03547 HuMAP2_03911 |
| FAM221B | HuMAP2_00357 HuMAP2_03547 HuMAP2_03911 |