hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00360
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DUSP7 | Dual specificity protein phosphatase 7 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase PYST2) | UniProt NCBI |
| DUSP9 | Dual specificity protein phosphatase 9 (EC 3.1.3.16) (EC 3.1.3.48) (Mitogen-activated protein kinase phosphatase 4) (MAP kinase phosphatase 4) (MKP-4) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-112409 | 0.000286582912066 | 1.0 | DUSP7 DUSP9 | RAF-independent MAPK1/3 activation |
| REAC:R-HSA-5675221 | 0.00111616502594 | 1.0 | DUSP7 DUSP9 | Negative regulation of MAPK pathway |
| GO:0017017 | 0.00270494046827 | 1.0 | DUSP7 DUSP9 | MAP kinase tyrosine/serine/threonine phosphatase activity |
| KEGG:04010 | 0.00476209584058 | 1.0 | DUSP7 DUSP9 | MAPK signaling pathway |
| WP:WP382 | 0.00889388896944 | 1.0 | DUSP7 DUSP9 | MAPK Signaling Pathway |
| GO:0033549 | 0.00946729163895 | 1.0 | DUSP7 DUSP9 | MAP kinase phosphatase activity |
| REAC:R-HSA-5673001 | 0.0313749631391 | 1.0 | DUSP7 DUSP9 | RAF/MAP kinase cascade |
| REAC:R-HSA-5684996 | 0.0330173681322 | 1.0 | DUSP7 DUSP9 | MAPK1/MAPK3 signaling |
| REAC:R-HSA-9607240 | 0.0371300843089 | 1.0 | DUSP7 DUSP9 | FLT3 Signaling |
| REAC:R-HSA-449836 | 0.0429891127334 | 1.0 | DUSP7 DUSP9 | Other interleukin signaling |
| REAC:R-HSA-5683057 | 0.0464733576116 | 1.0 | DUSP7 DUSP9 | MAPK family signaling cascades |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DUSP7 | DUSP9 | 1.0 | 0.949 | bioplex (DUSP7) bioplex_WMM |
Images
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Complex HuMAP2_00360 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DUSP7 | HuMAP2_00360 HuMAP2_01127 |
| DUSP9 | HuMAP2_00360 HuMAP2_01127 |