hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00368
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| FASN | Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)] | UniProt NCBI |
| CAD | CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)] | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00061 | 0.0347481262917 | 0.5 | FASN | Fatty acid biosynthesis |
| WP:WP2874 | 0.0443803979089 | 0.5 | FASN | Liver X Receptor Pathway |
| MIRNA:hsa-miR-486-3p | 0.0457232708071 | 1.0 | FASN CAD | hsa-miR-486-3p |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| FASN | CAD | 0.151 | 0.411 | hein_WMM bioplex (FASN) bioplex_WMM Guru boldt fraction boldt_WMM treiber_WMM |
Images
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Complex HuMAP2_00368 has an average edge precision of 0.411 which is ranked 3186 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| FASN | HuMAP2_00368 |
| CAD | HuMAP2_00368 HuMAP2_01301 HuMAP2_02414 HuMAP2_05612 |