hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_00380
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| H1-5 | Histone H1.5 (Histone H1a) (Histone H1b) (Histone H1s-3) | UniProt NCBI |
| H1-3 | Histone H1.3 (Histone H1c) (Histone H1s-2) | UniProt NCBI |
| NPM1 | Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin) | UniProt NCBI |
| NPM2 | Nucleoplasmin-2 | UniProt NCBI |
| SCML1 | Sex comb on midleg-like protein 1 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-140342 | 0.00105126658749 | 0.4 | H1-3 H1-5 | Apoptosis induced DNA fragmentation |
| REAC:R-HSA-2559584 | 0.00161668141155 | 0.4 | H1-3 H1-5 | Formation of Senescence-Associated Heterochromatin Foci (SAHF) |
| REAC:R-HSA-75153 | 0.0170965985867 | 0.4 | H1-3 H1-5 | Apoptotic execution phase |
| CORUM:3055 | 0.034094635807 | 0.4 | H1-3 NPM1 | Nop56p-associated pre-rRNA complex |
| REAC:R-HSA-2559586 | 0.0411580285567 | 0.4 | H1-3 H1-5 | DNA Damage/Telomere Stress Induced Senescence |
| CORUM:5154 | 0.0499494897235 | 0.2 | NPM1 | CTCF-nucleophosmin complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| H1-3 | NPM1 | 0.126 | 0.399 | hein_WMM boldt hein (NPM1) boldt_WMM treiber_WMM |
| NPM1 | NPM2 | 0.086 | 0.352 | bioplex (NPM2) bioplex_WMM |
| NPM1 | SCML1 | 0.049 | 0.293 | bioplex (NPM1) bioplex_WMM boldt boldt_WMM |
| H1-5 | NPM1 | 0.041 | 0.27 | hein_WMM hein (NPM1) fraction treiber_WMM |
| H1-3 | SCML1 | 0.007 | 0.002 | youn_WMM WMM_only |
| H1-5 | H1-3 | 0.0 | 0.012 | hein_WMM fraction treiber_WMM |
Images
Click to enlarge
Complex HuMAP2_00380 has an average edge precision of 0.221 which is ranked 5833 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| H1-5 | HuMAP2_00380 |
| H1-3 | HuMAP2_00380 HuMAP2_01156 HuMAP2_01921 HuMAP2_03549 HuMAP2_04252 HuMAP2_05025 |
| NPM1 | HuMAP2_00380 HuMAP2_01921 HuMAP2_02535 HuMAP2_03063 HuMAP2_03687 HuMAP2_06885 |
| NPM2 | HuMAP2_00380 HuMAP2_01921 HuMAP2_02535 |
| SCML1 | HuMAP2_00380 HuMAP2_03187 HuMAP2_04229 HuMAP2_04267 |