hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00386
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| GNPDA1 | Glucosamine-6-phosphate isomerase 1 (EC 3.5.99.6) (Glucosamine-6-phosphate deaminase 1) (GNPDA 1) (GlcN6P deaminase 1) (Oscillin) | UniProt NCBI |
| FEN1 | Flap endonuclease 1 (FEN-1) (EC 3.1.-.-) (DNase IV) (Flap structure-specific endonuclease 1) (Maturation factor 1) (MF1) (hFEN-1) | UniProt NCBI |
| HSPA5 | Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein) | UniProt NCBI |
| PGAM5 | Serine/threonine-protein phosphatase PGAM5, mitochondrial (EC 3.1.3.16) (Bcl-XL-binding protein v68) (Phosphoglycerate mutase family member 5) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7282 | 0.0499140284799 | 0.25 | FEN1 | FEN1-WRN complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| FEN1 | HSPA5 | 0.328 | 0.517 | bioplex (FEN1) gupta_WMM fraction boldt_WMM treiber_WMM bioplex_WMM |
| GNPDA1 | HSPA5 | 0.094 | 0.356 | bioplex (GNPDA1) fraction treiber_WMM |
| PGAM5 | HSPA5 | 0.048 | 0.293 | bioplex_WMM boldt gupta_WMM fraction boldt_WMM treiber_WMM |
| PGAM5 | FEN1 | 0.007 | 0.01 | gupta_WMM WMM_only treiber_WMM |
| GNPDA1 | FEN1 | 0.007 | 0.005 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_00386 has an average edge precision of 0.236 which is ranked 5594 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| GNPDA1 | HuMAP2_00268 HuMAP2_00386 HuMAP2_01020 HuMAP2_01831 |
| FEN1 | HuMAP2_00386 HuMAP2_01543 HuMAP2_05422 HuMAP2_06224 HuMAP2_06766 |
| HSPA5 | HuMAP2_00386 HuMAP2_01492 HuMAP2_03795 |
| PGAM5 | HuMAP2_00386 |