hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_00416
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PTPN6 | Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Protein-tyrosine phosphatase SHP-1) (SH-PTP1) | UniProt NCBI |
| PTPN2 | Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP) | UniProt NCBI |
| MUTYH | Adenine DNA glycosylase (EC 3.2.2.31) (MutY homolog) (hMYH) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9008059 | 0.000909962567223 | 0.666666666667 | PTPN2 PTPN6 | Interleukin-37 signaling |
| KEGG:04630 | 0.00323398213006 | 0.666666666667 | PTPN2 PTPN6 | JAK-STAT signaling pathway |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PTPN2 | MUTYH | 0.311 | 0.504 | bioplex (PTPN2) bioplex_WMM |
| PTPN2 | PTPN6 | 0.082 | 0.351 | fraction |
Images
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Complex HuMAP2_00416 has an average edge precision of 0.427 which is ranked 3045 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PTPN6 | HuMAP2_00416 HuMAP2_04220 |
| PTPN2 | HuMAP2_00416 HuMAP2_00859 HuMAP2_04566 HuMAP2_04914 |
| MUTYH | HuMAP2_00416 HuMAP2_04566 HuMAP2_04914 |