hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00422
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| GMPPB | Mannose-1-phosphate guanyltransferase beta (EC 2.7.7.13) (GDP-mannose pyrophosphorylase B) (GTP-mannose-1-phosphate guanylyltransferase beta) | UniProt NCBI |
| MMACHC | Methylmalonic aciduria and homocystinuria type C protein (EC 1.16.1.-) (CblC) (Cyanocobalamin reductase (cyanide-eliminating)) | UniProt NCBI |
| DHODH | Dihydroorotate dehydrogenase (quinone), mitochondrial (DHOdehase) (EC 1.3.5.2) (Dihydroorotate oxidase) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-3359474 | 0.0498572752401 | 0.333333333333 | MMACHC | Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MMACHC | GMPPB | 0.369 | 0.544 | bioplex (GMPPB) bioplex_WMM |
| GMPPB | DHODH | 0.095 | 0.359 | bioplex (GMPPB) bioplex_WMM |
| MMACHC | DHODH | 0.008 | 0.067 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_00422 has an average edge precision of 0.323 which is ranked 4296 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| GMPPB | HuMAP2_00422 HuMAP2_03528 HuMAP2_06536 |
| MMACHC | HuMAP2_00210 HuMAP2_00422 HuMAP2_00669 HuMAP2_06536 |
| DHODH | HuMAP2_00422 HuMAP2_06536 |