hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00432
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| OSM | Oncostatin-M (OSM) | UniProt NCBI |
| IL6ST | Interleukin-6 receptor subunit beta (IL-6 receptor subunit beta) (IL-6R subunit beta) (IL-6R-beta) (IL-6RB) (CDw130) (Interleukin-6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin-M receptor subunit alpha) (CD antigen CD130) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6788467 | 0.000110610948517 | 1.0 | IL6ST OSM | IL-6-type cytokine receptor ligand interactions |
| REAC:R-HSA-6783589 | 0.000286582912066 | 1.0 | IL6ST OSM | Interleukin-6 family signaling |
| WP:WP2374 | 0.000751123964743 | 1.0 | IL6ST OSM | Oncostatin M Signaling Pathway |
| KEGG:04630 | 0.00105921617042 | 1.0 | IL6ST OSM | JAK-STAT signaling pathway |
| KEGG:04060 | 0.0018558167614 | 1.0 | IL6ST OSM | Cytokine-cytokine receptor interaction |
| WP:WP236 | 0.00223362508365 | 1.0 | IL6ST OSM | Adipogenesis |
| GO:0038165 | 0.00270494046827 | 1.0 | IL6ST OSM | oncostatin-M-mediated signaling pathway |
| GO:0002675 | 0.0410249304355 | 1.0 | IL6ST OSM | positive regulation of acute inflammatory response |
| CORUM:3229 | 0.0499173803268 | 0.5 | IL6ST | CDK9-IL6ST complex |
| CORUM:5582 | 0.0499173803268 | 0.5 | IL6ST | LIFR-LIF-gp130 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| OSM | IL6ST | 0.764 | 0.749 | bioplex (OSM) bioplex_WMM |
Images
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Complex HuMAP2_00432 has an average edge precision of 0.749 which is ranked 1157 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| OSM | HuMAP2_00432 HuMAP2_05323 HuMAP2_05755 HuMAP2_06859 |
| IL6ST | HuMAP2_00432 HuMAP2_05323 HuMAP2_06859 |