hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00436
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NKRF | NF-kappa-B-repressing factor (NFkB-repressing factor) (Protein ITBA4) (Transcription factor NRF) | UniProt NCBI |
| C7orf50 | Uncharacterized protein C7orf50 | UniProt NCBI |
| RPL8 | 60S ribosomal protein L8 (Large ribosomal subunit protein uL2) | UniProt NCBI |
| RPL22L1 | 60S ribosomal protein L22-like 1 (Large ribosomal subunit protein eL22-like 1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:03010 | 0.016608760826 | 0.5 | RPL8 RPL22L1 | Ribosome |
| REAC:R-HSA-156902 | 0.0381968559025 | 0.5 | RPL8 RPL22L1 | Peptide chain elongation |
| REAC:R-HSA-192823 | 0.0381968559025 | 0.5 | RPL8 RPL22L1 | Viral mRNA Translation |
| REAC:R-HSA-156842 | 0.041754071825 | 0.5 | RPL8 RPL22L1 | Eukaryotic Translation Elongation |
| REAC:R-HSA-72764 | 0.041754071825 | 0.5 | RPL8 RPL22L1 | Eukaryotic Translation Termination |
| REAC:R-HSA-2408557 | 0.041754071825 | 0.5 | RPL8 RPL22L1 | Selenocysteine synthesis |
| REAC:R-HSA-975956 | 0.0435915557177 | 0.5 | RPL8 RPL22L1 | Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) |
| REAC:R-HSA-72689 | 0.0493392542359 | 0.5 | RPL8 RPL22L1 | Formation of a pool of free 40S subunits |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RPL8 | RPL22L1 | 0.992 | 0.912 | bioplex_WMM fraction treiber_WMM |
| RPL8 | C7orf50 | 0.815 | 0.773 | hein_WMM bioplex (RPL8) bioplex_WMM treiber_WMM |
| RPL8 | NKRF | 0.738 | 0.738 | hein_WMM bioplex (RPL8) bioplex_WMM boldt boldt_WMM treiber_WMM |
| C7orf50 | NKRF | 0.02 | 0.188 | bioplex_WMM gupta_WMM WMM_only |
| C7orf50 | RPL22L1 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| NKRF | RPL22L1 | 0.007 | 0.003 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_00436 has an average edge precision of 0.436 which is ranked 2968 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NKRF | HuMAP2_00436 HuMAP2_01878 HuMAP2_06948 |
| C7orf50 | HuMAP2_00436 HuMAP2_01878 HuMAP2_02216 HuMAP2_05730 |
| RPL8 | HuMAP2_00436 HuMAP2_01878 HuMAP2_02207 |
| RPL22L1 | HuMAP2_00436 HuMAP2_01878 HuMAP2_02870 |