hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00466
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| IL31RA | Interleukin-31 receptor subunit alpha (IL-31 receptor subunit alpha) (IL-31R subunit alpha) (IL-31R-alpha) (IL-31RA) (Cytokine receptor-like 3) (GLM-R) (hGLM-R) (Gp130-like monocyte receptor) (Gp130-like receptor) (ZcytoR17) | UniProt NCBI |
| NTHL1 | Endonuclease III-like protein 1 (hNTH1) (EC 3.2.2.-) (EC 4.2.99.18) (Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase) (DNA glycosylase/AP lyase) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9616333 | 0.0249595281251 | 0.5 | NTHL1 | Defective Base Excision Repair Associated with NTHL1 |
| REAC:R-HSA-9630222 | 0.0249595281251 | 0.5 | NTHL1 | Defective NTHL1 substrate binding |
| REAC:R-HSA-9630221 | 0.0249595281251 | 0.5 | NTHL1 | Defective NTHL1 substrate processing |
| REAC:R-HSA-9605308 | 0.0499173803268 | 0.5 | NTHL1 | Diseases of Base Excision Repair |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| IL31RA | NTHL1 | 0.021 | 0.185 | bioplex (IL31RA) bioplex_WMM |
Images
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Complex HuMAP2_00466 has an average edge precision of 0.185 which is ranked 6373 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| IL31RA | HuMAP2_00376 HuMAP2_00466 HuMAP2_02444 |
| NTHL1 | HuMAP2_00376 HuMAP2_00466 HuMAP2_02444 |