hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00496
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| EIF4A3 | Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Eukaryotic translation initiation factor 4A isoform 3) (Nuclear matrix protein 265) (NMP 265) (hNMP 265) [Cleaved into: Eukaryotic initiation factor 4A-III, N-terminally processed] | UniProt NCBI |
| SNRPB2 | U2 small nuclear ribonucleoprotein B'' (U2 snRNP B'') | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:03040 | 0.00122335090758 | 1.0 | EIF4A3 SNRPB2 | Spliceosome |
| CORUM:1181 | 0.00503279815751 | 1.0 | EIF4A3 SNRPB2 | C complex spliceosome |
| CORUM:351 | 0.0163067352889 | 1.0 | EIF4A3 SNRPB2 | Spliceosome |
| REAC:R-HSA-72163 | 0.0264008223028 | 1.0 | EIF4A3 SNRPB2 | mRNA Splicing - Major Pathway |
| REAC:R-HSA-72172 | 0.0288342631702 | 1.0 | EIF4A3 SNRPB2 | mRNA Splicing |
| REAC:R-HSA-72203 | 0.046079515598 | 1.0 | EIF4A3 SNRPB2 | Processing of Capped Intron-Containing Pre-mRNA |
| HP:0006355 | 0.0497341708567 | 0.5 | EIF4A3 | Agenesis of mandibular central incisor |
| HP:0008744 | 0.0497341708567 | 0.5 | EIF4A3 | Abnormality of the aryepiglottic fold |
| HP:0009094 | 0.0497341708567 | 0.5 | EIF4A3 | Cleft lower alveolar ridge |
| HP:0010752 | 0.0497341708567 | 0.5 | EIF4A3 | Cleft mandible |
| HP:0100499 | 0.0497341708567 | 0.5 | EIF4A3 | Tibial deviation of toes |
| HP:0200161 | 0.0497341708567 | 0.5 | EIF4A3 | Agenesis of mandibular incisor |
| CORUM:772 | 0.0499173803268 | 0.5 | EIF4A3 | EIF4A3-MLN51 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SNRPB2 | EIF4A3 | 0.917 | 0.84 | youn (EIF4A3) bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
Images
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Complex HuMAP2_00496 has an average edge precision of 0.84 which is ranked 813 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| EIF4A3 | HuMAP2_00496 HuMAP2_03995 |
| SNRPB2 | HuMAP2_00104 HuMAP2_00496 HuMAP2_02497 HuMAP2_03568 HuMAP2_05096 HuMAP2_06616 |